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pQCXIH-Flag-YAP-S127A Citations (15)

Originally described in: Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.
Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL Genes Dev. 2007 Nov 1. 21(21):2747-61.
PubMed Journal

Articles Citing pQCXIH-Flag-YAP-S127A

Articles
Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma. Slemmons KK, Crose LE, Rudzinski E, Bentley RC, Linardic CM. PLoS One. 2015 Oct 23;10(10):e0140781. doi: 10.1371/journal.pone.0140781. eCollection 2015. PubMed
Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutations. Troilo A, Benson EK, Esposito D, Garibsingh RA, Reddy EP, Mungamuri SK, Aaronson SA. Oncotarget. 2016 Apr 29. doi: 10.18632/oncotarget.9117. PubMed
Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow. Wang L, Luo JY, Li B, Tian XY, Chen LJ, Huang Y, Liu J, Deng D, Lau CW, Wan S, Ai D, Mak KK, Tong KK, Kwan KM, Wang N, Chiu JJ, Zhu Y, Huang Y. Nature. 2016 Dec 7. doi: 10.1038/nature20602. PubMed

Associated Plasmids

The Transcriptional Coactivator TAZ Is a Potent Mediator of Alveolar Rhabdomyosarcoma Tumorigenesis. Deel MD, Slemmons KK, Hinson AR, Genadry KC, Burgess BA, Crose LES, Kuprasertkul N, Oristian KM, Bentley RC, Linardic CM. Clin Cancer Res. 2018 Jun 1;24(11):2616-2630. doi: 10.1158/1078-0432.CCR-17-1207. Epub 2018 Mar 7. PubMed
YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1alpha. Mammoto A, Muyleart M, Kadlec A, Gutterman D, Mammoto T. Microvasc Res. 2018 Sep;119:73-83. doi: 10.1016/j.mvr.2018.04.003. Epub 2018 Apr 20. PubMed
Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling. Wu J, Minikes AM, Gao M, Bian H, Li Y, Stockwell BR, Chen ZN, Jiang X. Nature. 2019 Aug;572(7769):402-406. doi: 10.1038/s41586-019-1426-6. Epub 2019 Jul 24. PubMed
Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. Mammoto T, Torisawa YS, Muyleart M, Hendee K, Anugwom C, Gutterman D, Mammoto A. Aging (Albany NY). 2019 Sep 5;11(17):7051-7069. doi: 10.18632/aging.102236. Epub 2019 Sep 5. PubMed
The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2. Yang WH, Lin CC, Wu J, Chao PY, Chen K, Chen PH, Chi JT. Mol Cancer Res. 2021 Jun;19(6):1005-1014. doi: 10.1158/1541-7786.MCR-20-0534. Epub 2021 Mar 11. PubMed
RRBP1 rewires cisplatin resistance in oral squamous cell carcinoma by regulating Hippo pathway. Shriwas O, Arya R, Mohanty S, Mohapatra P, Kumar S, Rath R, Kaushik SR, Pahwa F, Murmu KC, Majumdar SKD, Muduly DK, Dixit A, Prasad P, Nanda RK, Dash R. Br J Cancer. 2021 Jun;124(12):2004-2016. doi: 10.1038/s41416-021-01336-7. Epub 2021 Mar 24. PubMed
Involvement of the TGF-beta Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis. Morice S, Danieau G, Tesfaye R, Mullard M, Brion R, Dupuy M, Ory B, Brounais-Le Royer B, Corre I, Redini F, Verrecchia F. Front Oncol. 2021 Oct 26;11:765711. doi: 10.3389/fonc.2021.765711. eCollection 2021. PubMed
Oncogenic Activation of YAP Signaling Sensitizes Ferroptosis of Hepatocellular Carcinoma via ALOXE3-Mediated Lipid Peroxidation Accumulation. Qin Y, Pei Z, Feng Z, Lin P, Wang S, Li Y, Huo F, Wang Q, Wang Z, Chen ZN, Wu J, Wang YF. Front Cell Dev Biol. 2021 Dec 16;9:751593. doi: 10.3389/fcell.2021.751593. eCollection 2021. PubMed
YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia. Hatterschide J, Castagnino P, Kim HW, Sperry SM, Montone KT, Basu D, White EA. Elife. 2022 Feb 16;11. pii: 75466. doi: 10.7554/eLife.75466. PubMed

Associated Plasmids

YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth. Vaidyanathan S, Salmi TM, Sathiqu RM, McConville MJ, Cox AG, Brown KK. Dev Cell. 2022 Mar 28;57(6):719-731.e8. doi: 10.1016/j.devcel.2022.02.004. Epub 2022 Feb 24. PubMed
A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation. Drozdz MM, Doane AS, Alkallas R, Desman G, Bareja R, Reilly M, Bang J, Yusupova M, You J, Eraslan Z, Wang JZ, Verma A, Aguirre K, Kane E, Watson IR, Elemento O, Piskounova E, Merghoub T, Zippin JH. Cell Rep. 2022 Sep 27;40(13):111412. doi: 10.1016/j.celrep.2022.111412. PubMed
Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors. Garcia-Rendueles MER, Krishnamoorthy G, Saqcena M, Acuna-Ruiz A, Revilla G, de Stanchina E, Knauf JA, Lester R, Xu B, Ghossein RA, Fagin JA. Mol Cancer. 2022 Dec 7;21(1):213. doi: 10.1186/s12943-022-01676-9. PubMed

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