myc-hULK1 Citations (14)
Originally described in: ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery.Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, Kundu M, Kim DH Mol Biol Cell. 2009 Apr;20(7):1992-2003. Epub 2009 Feb 18. PubMed Journal
Articles Citing myc-hULK1
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| DAP1, a negative regulator of autophagy, controls SubAB-mediated apoptosis and autophagy. Yahiro K, Tsutsuki H, Ogura K, Nagasawa S, Moss J, Noda M. Infect Immun. 2014 Nov;82(11):4899-908. doi: 10.1128/IAI.02213-14. Epub 2014 Sep 2. PubMed |
| Upregulation of Unc-51-like kinase 1 by nitric oxide stabilizes SIRT1, independent of autophagy. Xing J, Liu H, Yang H, Chen R, Chen Y, Xu J. PLoS One. 2014 Dec 26;9(12):e116165. doi: 10.1371/journal.pone.0116165. eCollection 2014. PubMed |
| Autophagy protein Ulk1 promotes mitochondrial apoptosis through reactive oxygen species. Mukhopadhyay S, Das DN, Panda PK, Sinha N, Naik PP, Bissoyi A, Pramanik K, Bhutia SK. Free Radic Biol Med. 2015 Dec;89:311-21. doi: 10.1016/j.freeradbiomed.2015.07.159. Epub 2015 Sep 25. PubMed |
| Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency. Farah BL, Landau DJ, Sinha RA, Brooks ED, Wu Y, Fung SY, Tanaka T, Hirayama M, Bay BH, Koeberl DD, Yen PM. J Hepatol. 2016 Feb;64(2):370-9. doi: 10.1016/j.jhep.2015.10.008. Epub 2015 Oct 20. PubMed |
| Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo. Zhang L, Fu L, Zhang S, Zhang J, Zhao Y, Zheng Y, He G, Yang S, Ouyang L, Liu B. Chem Sci. 2017 Apr 1;8(4):2687-2701. doi: 10.1039/c6sc05368h. Epub 2017 Jan 9. PubMed |
| A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B. Pengo N, Agrotis A, Prak K, Jones J, Ketteler R. Nat Commun. 2017 Aug 18;8(1):294. doi: 10.1038/s41467-017-00303-2. PubMed |
| MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process. Colecchia D, Dapporto F, Tronnolone S, Salvini L, Chiariello M. J Biol Chem. 2018 Oct 12;293(41):15962-15976. doi: 10.1074/jbc.RA118.002527. Epub 2018 Aug 21. PubMed |
| Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region. Izumi H, Li Y, Shibaki M, Mori D, Yasunami M, Sato S, Matsunaga H, Mae T, Kodama K, Kamijo T, Kaneko Y, Nakagawara A. Sci Rep. 2019 Feb 19;9(1):2236. doi: 10.1038/s41598-019-39229-8. PubMed |
| Protective autophagy elicited by RAF-->MEK-->ERK inhibition suggests a treatment strategy for RAS-driven cancers. Kinsey CG, Camolotto SA, Boespflug AM, Guillen KP, Foth M, Truong A, Schuman SS, Shea JE, Seipp MT, Yap JT, Burrell LD, Lum DH, Whisenant JR, Gilcrease GW 3rd, Cavalieri CC, Rehbein KM, Cutler SL, Affolter KE, Welm AL, Welm BE, Scaife CL, Snyder EL, McMahon M. Nat Med. 2019 Apr;25(4):620-627. doi: 10.1038/s41591-019-0367-9. Epub 2019 Mar 4. PubMed |
| The PARK10 gene USP24 is a negative regulator of autophagy and ULK1 protein stability. Thayer JA, Awad O, Hegdekar N, Sarkar C, Tesfay H, Burt C, Zeng X, Feldman RA, Lipinski MM. Autophagy. 2019 Apr 7:1-14. doi: 10.1080/15548627.2019.1598754. PubMed |
| Autophagy-induced senescence is regulated by p38alpha signaling. Slobodnyuk K, Radic N, Ivanova S, Llado A, Trempolec N, Zorzano A, Nebreda AR. Cell Death Dis. 2019 May 15;10(6):376. doi: 10.1038/s41419-019-1607-0. PubMed |
| The Autophagy-Initiating Protein Kinase ULK1 Phosphorylates Human Cytomegalovirus Tegument Protein pp28 and Regulates Efficient Virus Release. Konig P, Svrlanska A, Read C, Feichtinger S, Stamminger T. J Virol. 2021 Feb 24;95(6). pii: JVI.02346-20. doi: 10.1128/JVI.02346-20. Print 2021 Feb 24. PubMed |
| Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms. Saleiro D, Wen JQ, Kosciuczuk EM, Eckerdt F, Beauchamp EM, Oku CV, Blyth GT, Fischietti M, Ilut L, Colamonici M, Palivos W, Atsaves PA, Tan D, Kocherginsky M, Weinberg RS, Fish EN, Crispino JD, Hoffman R, Platanias LC. Nat Commun. 2022 Apr 1;13(1):1750. doi: 10.1038/s41467-022-29381-7. PubMed |
| Gemigliptin, a DPP4 inhibitor, ameliorates nonalcoholic steatohepatitis through AMP-activated protein kinase-independent and ULK1-mediated autophagy. Song Y, Yang H, Kim J, Lee Y, Kim SH, Do IG, Park CY. Mol Metab. 2023 Dec;78:101806. doi: 10.1016/j.molmet.2023.101806. Epub 2023 Sep 20. PubMed |
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