wtTDP43tdTOMATOHA Citations (13)

Originally described in: The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism.
Yang C, Tan W, Whittle C, Qiu L, Cao L, Akbarian S, Xu Z PLoS One. 2010 . 5(12):e15878. PubMed Journal

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Articles Citing wtTDP43tdTOMATOHA

Articles
Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions. Farrawell NE, Lambert-Smith IA, Warraich ST, Blair IP, Saunders DN, Hatters DM, Yerbury JJ. Sci Rep. 2015 Aug 21;5:13416. doi: 10.1038/srep13416. PubMed
The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification. Liu Y, Miao K, Dunham NP, Liu H, Fares M, Boal AK, Li X, Zhang X. Biochemistry. 2017 Mar 21;56(11):1585-1595. doi: 10.1021/acs.biochem.7b00056. Epub 2017 Mar 13. PubMed
Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity. Woo JA, Liu T, Trotter C, Fang CC, De Narvaez E, LePochat P, Maslar D, Bukhari A, Zhao X, Deonarine A, Westerheide SD, Kang DE. Nat Commun. 2017 Jun 6;8:15558. doi: 10.1038/ncomms15558. PubMed
Clusterin protects neurons against intracellular proteotoxicity. Gregory JM, Whiten DR, Brown RA, Barros TP, Kumita JR, Yerbury JJ, Satapathy S, McDade K, Smith C, Luheshi LM, Dobson CM, Wilson MR. Acta Neuropathol Commun. 2017 Nov 7;5(1):81. doi: 10.1186/s40478-017-0481-1. PubMed
Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization. Pinarbasi ES, Cagatay T, Fung HYJ, Li YC, Chook YM, Thomas PJ. Sci Rep. 2018 May 4;8(1):7083. doi: 10.1038/s41598-018-25008-4. PubMed
Fluorescence detection of DNA mismatch repair in human cells. Ito S, Shiraishi M, Tsuchihashi K, Takatsuka R, Yamamoto J, Kuraoka I, Iwai S. Sci Rep. 2018 Aug 15;8(1):12181. doi: 10.1038/s41598-018-30733-x. PubMed
N-terminal Domain of TDP43 Enhances Liquid-Liquid Phase Separation of Globular Proteins. Carter GC, Hsiung CH, Simpson L, Yang H, Zhang X. J Mol Biol. 2021 May 14;433(10):166948. doi: 10.1016/j.jmb.2021.166948. Epub 2021 Mar 18. PubMed
TDP-43 and PINK1 mediate CHCHD10(S59L) mutation-induced defects in Drosophila and in vitro. Baek M, Choe YJ, Bannwarth S, Kim J, Maitra S, Dorn GW 2nd, Taylor JP, Paquis-Flucklinger V, Kim NC. Nat Commun. 2021 Mar 26;12(1):1924. doi: 10.1038/s41467-021-22145-9. PubMed
Novel chemical inhibitor against SOD1 misfolding and aggregation protects neuron-loss and ameliorates disease symptoms in ALS mouse model. Woo TG, Yoon MH, Kang SM, Park S, Cho JH, Hwang YJ, Ahn J, Jang H, Shin YJ, Jung EM, Ha NC, Kim BH, Kwon Y, Park BJ. Commun Biol. 2021 Dec 15;4(1):1397. doi: 10.1038/s42003-021-02862-z. PubMed
A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43. Cascella R, Bigi A, Riffert DG, Gagliani MC, Ermini E, Moretti M, Cortese K, Cecchi C, Chiti F. Sci Adv. 2022 Jul 29;8(30):eabm6376. doi: 10.1126/sciadv.abm6376. Epub 2022 Jul 27. PubMed
Nuclear bodies protect phase separated proteins from degradation in stressed proteome. Jung KH, Sun J, Hsiung CH, Lian XL, Liu Y, Zhang X. bioRxiv. 2023 Apr 21:2023.04.19.537522. doi: 10.1101/2023.04.19.537522. Preprint. PubMed
Intracellular RNA and DNA tracking by uridine-rich internal loop tagging with fluorogenic bPNA. Liang Y, Willey S, Chung YC, Lo YM, Miao S, Rundell S, Tu LC, Bong D. Nat Commun. 2023 May 24;14(1):2987. doi: 10.1038/s41467-023-38579-2. PubMed
Detecting protein-protein interaction during liquid-liquid phase separation using fluorogenic protein sensors. Huang Y, Chen J, Hsiung CH, Bai Y, Tan Z, Ye S, Zhang X. Mol Biol Cell. 2024 Mar 1;35(3):ar41. doi: 10.1091/mbc.E23-11-0442. Epub 2024 Jan 17. PubMed

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