HA-p62 Citations (48)
Originally described in: Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy.Fan W, Tang Z, Chen D, Moughon D, Ding X, Chen S, Zhu M, Zhong Q Autophagy. 2010 Jul 22. 6(5):. PubMed Journal
Articles Citing HA-p62
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| p62/SQSTM1 synergizes with autophagy for tumor growth in vivo. Wei H, Wang C, Croce CM, Guan JL. Genes Dev. 2014 Jun 1;28(11):1204-16. doi: 10.1101/gad.237354.113. PubMed |
| FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Dunlop EA, Seifan S, Claessens T, Behrends C, Kamps MA, Rozycka E, Kemp AJ, Nookala RK, Blenis J, Coull BJ, Murray JT, van Steensel MA, Wilkinson S, Tee AR. Autophagy. 2014 Oct 1;10(10):1749-60. doi: 10.4161/auto.29640. Epub 2014 Jul 22. PubMed |
| Interferon-stimulated gene 15 (ISG15) and ISG15-linked proteins can associate with members of the selective autophagic process, histone deacetylase 6 (HDAC6) and SQSTM1/p62. Nakashima H, Nguyen T, Goins WF, Chiocca EA. J Biol Chem. 2015 Jan 16;290(3):1485-95. doi: 10.1074/jbc.M114.593871. Epub 2014 Nov 26. PubMed |
| The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells. Rui YN, Xu Z, Chen Z, Zhang S. Autophagy. 2015;11(5):812-32. doi: 10.1080/15548627.2015.1034402. PubMed |
| Actin nucleation by WH2 domains at the autophagosome. Coutts AS, La Thangue NB. Nat Commun. 2015 Jul 30;6:7888. doi: 10.1038/ncomms8888. PubMed |
| ATM functions at the peroxisome to induce pexophagy in response to ROS. Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL. Nat Cell Biol. 2015 Oct;17(10):1259-69. doi: 10.1038/ncb3230. Epub 2015 Sep 7. PubMed |
| Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease. Keane H, Ryan BJ, Jackson B, Whitmore A, Wade-Martins R. Sci Rep. 2015 Nov 26;5:17004. doi: 10.1038/srep17004. PubMed |
| mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Villar VH, Nguyen TL, Delcroix V, Teres S, Bouchecareilh M, Salin B, Bodineau C, Vacher P, Priault M, Soubeyran P, Duran RV. Nat Commun. 2017 Jan 23;8:14124. doi: 10.1038/ncomms14124. PubMed |
| p62-Mediated mitochondrial clustering attenuates apoptosis induced by mitochondrial depolarization. Xiao B, Deng X, Lim GGY, Zhou W, Saw WT, Zhou ZD, Lim KL, Tan EK. Biochim Biophys Acta. 2017 Jul;1864(7):1308-1317. doi: 10.1016/j.bbamcr.2017.04.009. Epub 2017 Apr 19. PubMed |
| p62/sequestosome 1 in human colorectal carcinoma as a potent prognostic predictor associated with cell proliferation. Nakayama S, Karasawa H, Suzuki T, Yabuuchi S, Takagi K, Aizawa T, Onodera Y, Nakamura Y, Watanabe M, Fujishima F, Yoshida H, Morikawa T, Sase T, Naitoh T, Unno M, Sasano H. Cancer Med. 2017 Jun;6(6):1264-1274. doi: 10.1002/cam4.1093. Epub 2017 May 23. PubMed |
| MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability. Liu L, He J, Wei X, Wan G, Lao Y, Xu W, Li Z, Hu H, Hu Z, Luo X, Wu J, Xie W, Zhang Y, Xu N. Oncogene. 2017 Oct 19;36(42):5874-5884. doi: 10.1038/onc.2017.193. Epub 2017 Jun 19. PubMed |
| Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells. Ha S, Jeong SH, Yi K, Chung KM, Hong CJ, Kim SW, Kim EK, Yu SW. J Biol Chem. 2017 Jun 27. pii: jbc.M117.780874. doi: 10.1074/jbc.M117.780874. PubMed |
| Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation. Sample A, Zhao B, Qiang L, He YY. J Biol Chem. 2017 Sep 8;292(36):14786-14795. doi: 10.1074/jbc.M117.786160. Epub 2017 Jul 19. PubMed |
| HSPB8 and BAG3 cooperate to promote spatial sequestration of ubiquitinated proteins and coordinate the cellular adaptive response to proteasome insufficiency. Guilbert SM, Lambert H, Rodrigue MA, Fuchs M, Landry J, Lavoie JN. FASEB J. 2018 Jul;32(7):3518-3535. doi: 10.1096/fj.201700558RR. Epub 2018 Feb 5. PubMed |
| P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity. Kalogeropulou AF, Zhao J, Bolliger MF, Memou A, Narasimha S, Molitor TP, Wilson WH, Rideout HJ, Nichols RJ. Biochem J. 2018 Apr 9;475(7):1271-1293. doi: 10.1042/BCJ20170699. PubMed |
| A proximity-dependent biotinylation (BioID) approach flags the p62/sequestosome-1 protein as a caspase-1 substrate. Jamilloux Y, Lagrange B, Di Micco A, Bourdonnay E, Provost A, Tallant R, Henry T, Martinon F. J Biol Chem. 2018 Aug 10;293(32):12563-12575. doi: 10.1074/jbc.RA117.000435. Epub 2018 Jun 21. PubMed |
| DEAD Box Protein 5 Inhibits Liver Tumorigenesis by Stimulating Autophagy via Interaction with p62/SQSTM1. Zhang H, Zhang Y, Zhu X, Chen C, Zhang C, Xia Y, Zhao Y, Andrisani O, Kong L. Hepatology. 2019 Mar;69(3):1046-1063. doi: 10.1002/hep.30300. Epub 2019 Feb 8. PubMed |
| The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy. Mehto S, Jena KK, Nath P, Chauhan S, Kolapalli SP, Das SK, Sahoo PK, Jain A, Taylor GA, Chauhan S. Mol Cell. 2019 Feb 7;73(3):429-445.e7. doi: 10.1016/j.molcel.2018.11.018. Epub 2019 Jan 3. PubMed |
| The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics. Li Y, Merkel CD, Zeng X, Heier JA, Cantrell PS, Sun M, Stolz DB, Watkins SC, Yates NA, Kwiatkowski AV. J Cell Sci. 2019 Feb 11;132(3). pii: jcs.221606. doi: 10.1242/jcs.221606. PubMed |
| Lamin B is a target for selective nuclear PQC by BAG3: implication for nuclear envelopathies. Gupta MK, Gordon J, Glauser GM, Myers VD, Feldman AM, Cheung JY, Khalili K. Cell Death Dis. 2019 Jan 10;10(1):23. doi: 10.1038/s41419-018-1255-9. PubMed |
| PIM kinases mediate resistance of glioblastoma cells to TRAIL by a p62/SQSTM1-dependent mechanism. Serrano-Saenz S, Palacios C, Delgado-Bellido D, Lopez-Jimenez L, Garcia-Diaz A, Soto-Serrano Y, Casal JI, Bartolome RA, Fernandez-Luna JL, Lopez-Rivas A, Oliver FJ. Cell Death Dis. 2019 Jan 18;10(2):51. doi: 10.1038/s41419-018-1293-3. PubMed |
| Regulation of death receptor signaling by the autophagy protein TP53INP2. Ivanova S, Polajnar M, Narbona-Perez AJ, Hernandez-Alvarez MI, Frager P, Slobodnyuk K, Plana N, Nebreda AR, Palacin M, Gomis RR, Behrends C, Zorzano A. EMBO J. 2019 May 15;38(10). pii: embj.201899300. doi: 10.15252/embj.201899300. Epub 2019 Apr 12. PubMed |
| The ICP0 Protein of Herpes Simplex Virus 1 (HSV-1) Downregulates Major Autophagy Adaptor Proteins Sequestosome 1 and Optineurin during the Early Stages of HSV-1 Infection. Waisner H, Kalamvoki M. J Virol. 2019 Oct 15;93(21). pii: JVI.01258-19. doi: 10.1128/JVI.01258-19. Print 2019 Nov 1. PubMed |
| Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation. Wang K, Tu Y, Wan JB, Chen M, He C. Carcinogenesis. 2019 Aug 27. pii: 5554930. doi: 10.1093/carcin/bgz140. PubMed |
| Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity. Ye J, Cheung J, Gerbino V, Ahlsen G, Zimanyi C, Hirsh D, Maniatis T. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24517-24526. doi: 10.1073/pnas.1915732116. Epub 2019 Nov 20. PubMed |
| p62 is Negatively Implicated in the TRAF6-BECN1 Signaling Axis for Autophagy Activation and Cancer Progression by Toll-Like Receptor 4 (TLR4). Kim MJ, Min Y, Im JS, Son J, Lee JS, Lee KY. Cells. 2020 May 6;9(5). pii: cells9051142. doi: 10.3390/cells9051142. PubMed |
| Characterization of MORN2 stability and regulatory function in LC3-associated phagocytosis in macrophages. Morita M, Kajiye M, Sakurai C, Kubo S, Takahashi M, Kinoshita D, Hori N, Hatsuzawa K. Biol Open. 2020 Jun 23;9(6). pii: bio.051029. doi: 10.1242/bio.051029. PubMed |
| Shikonin suppresses trophoblast cell growth via regulation of GLI1, and p62 mediated caspase 8 activation. Wang Y, Zhu F, Zhang Y, Chen C, Lai Y, Sun J, Chen S, Qiu P, Gao J, Deng G. Reprod Toxicol. 2020 Aug;95:104-112. doi: 10.1016/j.reprotox.2020.05.011. Epub 2020 May 24. PubMed |
| The Autophagy Machinery Contributes to E-cadherin Turnover in Breast Cancer. Damiano V, Spessotto P, Vanin G, Perin T, Maestro R, Santarosa M. Front Cell Dev Biol. 2020 Jun 30;8:545. doi: 10.3389/fcell.2020.00545. eCollection 2020. PubMed |
| Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination. Blazquez C, Ruiz-Calvo A, Bajo-Graneras R, Baufreton JM, Resel E, Varilh M, Pagano Zottola AC, Mariani Y, Cannich A, Rodriguez-Navarro JA, Marsicano G, Galve-Roperh I, Bellocchio L, Guzman M. Elife. 2020 Aug 10;9. pii: 56811. doi: 10.7554/eLife.56811. PubMed |
| BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62. Friesen EL, Zhang YT, Earnshaw R, De Snoo ML, O'Hara DM, Agapova V, Chau H, Ngana S, Chen KS, Kalia LV, Kalia SK. Front Cell Dev Biol. 2020 Aug 4;8:716. doi: 10.3389/fcell.2020.00716. eCollection 2020. PubMed |
| The interactome of multifunctional HAX1 protein suggests its role in the regulation of energy metabolism, de-aggregation, cytoskeleton organization and RNA-processing. Wakula M, Balcerak A, Rubel T, Chmielarczyk M, Konopinski R, Lyczek F, Grzybowska EA. Biosci Rep. 2020 Nov 27;40(11). pii: 226900. doi: 10.1042/BSR20203094. PubMed |
| The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy. Yla-Anttila P, Gupta S, Masucci MG. Autophagy. 2021 Nov;17(11):3461-3474. doi: 10.1080/15548627.2021.1874660. Epub 2021 Jan 28. PubMed |
| Annexin-A1 SUMOylation regulates microglial polarization after cerebral ischemia by modulating IKKalpha stability via selective autophagy. Li X, Xia Q, Mao M, Zhou H, Zheng L, Wang Y, Zeng Z, Yan L, Zhao Y, Shi J. Sci Adv. 2021 Jan 20;7(4). pii: 7/4/eabc5539. doi: 10.1126/sciadv.abc5539. Print 2021 Jan. PubMed |
| iTRAQ-based analysis for the identification of MARCH8 targets in human esophageal squamous cell carcinoma. Singh S, Bano A, Saraya A, Das P, Sharma R. J Proteomics. 2021 Mar 30;236:104125. doi: 10.1016/j.jprot.2021.104125. Epub 2021 Feb 2. PubMed |
| Epigenetic regulation of p62/SQSTM1 overcomes the radioresistance of head and neck cancer cells via autophagy-dependent senescence induction. Lee M, Nam HY, Kang HB, Lee WH, Lee GH, Sung GJ, Han MW, Cho KJ, Chang EJ, Choi KC, Kim SW, Kim SY. Cell Death Dis. 2021 Mar 5;12(3):250. doi: 10.1038/s41419-021-03539-5. PubMed |
| Autophagy of the m(6)A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, He YY. Nat Commun. 2021 Apr 12;12(1):2183. doi: 10.1038/s41467-021-22469-6. PubMed |
| UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling. Torrino S, Tiroille V, Dolfi B, Dufies M, Hinault C, Bonesso L, Dagnino S, Uhler J, Irondelle M, Gay AS, Fleuriot L, Debayle D, Lacas-Gervais S, Cormont M, Bertero T, Bost F, Gilleron J, Clavel S. Elife. 2021 Apr 22;10. pii: 68348. doi: 10.7554/eLife.68348. PubMed |
| Inhibition of selective autophagy by members of the herpesvirus ubiquitin-deconjugase family. Yla-Anttila P, Masucci MG. Biochem J. 2021 Jun 25;478(12):2297-2308. doi: 10.1042/BCJ20210225. PubMed |
| BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters. Kannangara AR, Poole DM, McEwan CM, Youngs JC, Weerasekara VK, Thornock AM, Lazaro MT, Balasooriya ER, Oh LM, Soderblom EJ, Lee JJ, Simmons DL, Andersen JL. EMBO Rep. 2021 Aug 9:e51136. doi: 10.15252/embr.202051136. PubMed |
| USP8 regulates liver cancer progression via the inhibition of TRAF6-mediated signal for NF-kappaB activation and autophagy induction by TLR4. Kim MJ, Choi B, Kim JY, Min Y, Kwon DH, Son J, Lee JS, Lee JS, Chun E, Lee KY. Transl Oncol. 2022 Jan;15(1):101250. doi: 10.1016/j.tranon.2021.101250. Epub 2021 Oct 20. PubMed |
| The caspase-6-p62 axis modulates p62 droplets based autophagy in a dominant-negative manner. Valionyte E, Yang Y, Griffiths SA, Bone AT, Barrow ER, Sharma V, Lu B, Luo S. Cell Death Differ. 2021 Dec 3. pii: 10.1038/s41418-021-00912-x. doi: 10.1038/s41418-021-00912-x. PubMed |
| USP17 is required for peripheral trafficking of lysosomes. Lin J, McCann AP, Sereesongsaeng N, Burden JM, Alsa'd AA, Burden RE, Micu I, Williams R, Van Schaeybroeck S, Evergren E, Mullan P, Simpson JC, Scott CJ, Burrows JF. EMBO Rep. 2022 Apr 5;23(4):e51932. doi: 10.15252/embr.202051932. Epub 2022 Jan 26. PubMed |
| ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function. Baron DM, Fenton AR, Saez-Atienzar S, Giampetruzzi A, Sreeram A, Shankaracharya, Keagle PJ, Doocy VR, Smith NJ, Danielson EW, Andresano M, McCormack MC, Garcia J, Bercier V, Van Den Bosch L, Brent JR, Fallini C, Traynor BJ, Holzbaur ELF, Landers JE. Cell Rep. 2022 Apr 5;39(1):110598. doi: 10.1016/j.celrep.2022.110598. PubMed |
| The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein. Bonavita R, Scerra G, Di Martino R, Nuzzo S, Polishchuk E, Di Gennaro M, Williams SV, Caporaso MG, Caiazza C, Polishchuk R, D'Agostino M, Fleming A, Renna M. Hum Mol Genet. 2023 Jul 4;32(14):2269-2291. doi: 10.1093/hmg/ddad047. PubMed |
| Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome. Li Q, Zhang Q, Kim YR, Gaddam RR, Jacobs JS, Bachschmid MM, Younis T, Zhu Z, Zingman L, London B, Rauckhorst AJ, Taylor EB, Norris AW, Vikram A, Irani K. Nat Commun. 2023 Sep 11;14(1):5595. doi: 10.1038/s41467-023-41351-1. PubMed |
| Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model. Xue R, Fan XL, Yang Q, Yu C, Lu TY, Wan GM. Phytomedicine. 2023 Dec;121:155097. doi: 10.1016/j.phymed.2023.155097. Epub 2023 Sep 20. PubMed |
| Autophagy regulates tumor growth and metastasis. Qiang L, Zhao B, Ming M, Wang N, He TC, Hwang S, Thorburn A, He YY. bioRxiv [Preprint]. 2023 Nov 3:2023.10.31.564991. doi: 10.1101/2023.10.31.564991. PubMed |
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