pRS416Gal TDP43 WT YFP Citations (4)
Originally described in: TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity.Johnson BS, Snead D, Lee JJ, McCaffery JM, Shorter J, Gitler AD J Biol Chem. 2009 Jul 24. 284(30):20329-39. PubMed Journal
Articles Citing pRS416Gal TDP43 WT YFP
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Use of ade1 and ade2 mutations for development of a versatile red/white colour assay of amyloid-induced oxidative stress in saccharomyces cerevisiae. Bharathi V, Girdhar A, Prasad A, Verma M, Taneja V, Patel BK. Yeast. 2016 Dec;33(12):607-620. doi: 10.1002/yea.3209. Epub 2016 Oct 13. PubMed |
An acridine derivative, [4,5-bis{(N-carboxy methyl imidazolium)methyl}acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models. Prasad A, Raju G, Sivalingam V, Girdhar A, Verma M, Vats A, Taneja V, Prabusankar G, Patel BK. Sci Rep. 2016 Dec 21;6:39490. doi: 10.1038/srep39490. PubMed |
Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies. Park S, Park SK, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova TA, Liebman SW. PLoS Genet. 2019 Aug 7;15(8):e1008308. doi: 10.1371/journal.pgen.1008308. eCollection 2019 Aug. PubMed |
Elevated constitutive expression of Hsp40 chaperone Sis1 reduces TDP-43 aggregation-induced oxidative stress in Ire1 pathway dependent-manner in yeast TDP-43 proteinopathy model of amyotrophic lateral sclerosis. Bharathi V, Bajpai A, Parappuram IT, Patel BK. Biochem Biophys Res Commun. 2022 Mar 5;595:28-34. doi: 10.1016/j.bbrc.2022.01.073. Epub 2022 Jan 22. PubMed |
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