pCMV-flag S127A YAP Citations (28)
Originally described in: Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL Genes Dev. 2007 Nov 1. 21(21):2747-61. PubMed Journal
Articles Citing pCMV-flag S127A YAP
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| LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap. Nguyen HB, Babcock JT, Wells CD, Quilliam LA. Oncogene. 2013 Aug 29;32(35):4100-9. doi: 10.1038/onc.2012.431. Epub 2012 Oct 1. PubMed |
| The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP. Kimura TE, Duggirala A, Smith MC, White S, Sala-Newby GB, Newby AC, Bond M. J Mol Cell Cardiol. 2016 Jan;90:1-10. doi: 10.1016/j.yjmcc.2015.11.024. Epub 2015 Nov 25. PubMed |
| Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse. Corvaisier M, Bauzone M, Corfiotti F, Renaud F, El Amrani M, Monte D, Truant S, Leteurtre E, Formstecher P, Van Seuningen I, Gespach C, Huet G. Oncotarget. 2016 Aug 30;7(35):56699-56712. doi: 10.18632/oncotarget.11057. PubMed |
| Proproliferative and antiapoptotic action of exogenously introduced YAP in pancreatic beta cells. Yuan T, Rafizadeh S, Azizi Z, Lupse B, Gorrepati KD, Awal S, Oberholzer J, Maedler K, Ardestani A. JCI Insight. 2016 Nov 3;1(18):e86326. PubMed |
| An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice. Hu JK, Du W, Shelton SJ, Oldham MC, DiPersio CM, Klein OD. Cell Stem Cell. 2017 Jul 6;21(1):91-106.e6. doi: 10.1016/j.stem.2017.03.023. Epub 2017 Apr 27. PubMed |
| Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP. Zhang D, Yang S, Toledo EM, Gyllborg D, Salto C, Carlos Villaescusa J, Arenas E. Sci Signal. 2017 Aug 22;10(493). pii: 10/493/eaal4165. doi: 10.1126/scisignal.aal4165. PubMed |
| Polo-Like Kinase 2 is Dynamically Regulated to Coordinate Proliferation and Early Lineage Specification Downstream of Yes-Associated Protein 1 in Cardiac Progenitor Cells. Mochizuki M, Lorenz V, Ivanek R, Della Verde G, Gaudiello E, Marsano A, Pfister O, Kuster GM. J Am Heart Assoc. 2017 Oct 24;6(10). pii: JAHA.117.005920. doi: 10.1161/JAHA.117.005920. PubMed |
| Sulforaphane reduces YAP/Np63alpha signaling to reduce cancer stem cell survival and tumor formation. Fisher ML, Ciavattone N, Grun D, Adhikary G, Eckert RL. Oncotarget. 2017 Aug 27;8(43):73407-73418. doi: 10.18632/oncotarget.20562. eCollection 2017 Sep 26. PubMed |
| Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells. Fisher ML, Grun D, Adhikary G, Xu W, Eckert RL. Oncotarget. 2017 Nov 22;8(66):110257-110272. doi: 10.18632/oncotarget.22628. eCollection 2017 Dec 15. PubMed |
| YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development. Neto F, Klaus-Bergmann A, Ong YT, Alt S, Vion AC, Szymborska A, Carvalho JR, Hollfinger I, Bartels-Klein E, Franco CA, Potente M, Gerhardt H. Elife. 2018 Feb 5;7. pii: 31037. doi: 10.7554/eLife.31037. PubMed |
| SS18-SSX-Dependent YAP/TAZ Signaling in Synovial Sarcoma. Isfort I, Cyra M, Elges S, Kailayangiri S, Altvater B, Rossig C, Steinestel K, Grunewald I, Huss S, Esseling E, Mikesch JH, Hafner S, Simmet T, Wozniak A, Schoffski P, Larsson O, Wardelmann E, Trautmann M, Hartmann W. Clin Cancer Res. 2019 Jun 15;25(12):3718-3731. doi: 10.1158/1078-0432.CCR-17-3553. Epub 2019 Feb 27. PubMed |
| The tumor suppressor RASSF1A modulates inflammation and injury in the reperfused murine myocardium. Francisco J, Byun J, Zhang Y, Kalloo OB, Mizushima W, Oka S, Zhai P, Sadoshima J, Del Re DP. J Biol Chem. 2019 Aug 30;294(35):13131-13144. doi: 10.1074/jbc.RA119.008970. Epub 2019 Jul 16. PubMed |
| DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression. Jimenez-Martinez M, Ostale CM, van der Burg LR, Galan-Martinez J, Hardwick JCH, Lopez-Perez R, Hawinkels LJAC, Stamatakis K, Fresno M. Cancers (Basel). 2019 Nov 9;11(11). pii: cancers11111767. doi: 10.3390/cancers11111767. PubMed |
| The YAP1 Signaling Inhibitors, Verteporfin and CA3, Suppress the Mesothelioma Cancer Stem Cell Phenotype. Kandasamy S, Adhikary G, Rorke EA, Friedberg JS, Mickle MB, Alexander HR, Eckert RL. Mol Cancer Res. 2020 Mar;18(3):343-351. doi: 10.1158/1541-7786.MCR-19-0914. Epub 2019 Nov 15. PubMed |
| YAP-Mediated Recruitment of YY1 and EZH2 Represses Transcription of Key Cell-Cycle Regulators. Hoxha S, Shepard A, Troutman S, Diao H, Doherty JR, Janiszewska M, Witwicki RM, Pipkin ME, Ja WW, Kareta MS, Kissil JL. Cancer Res. 2020 Jun 15;80(12):2512-2522. doi: 10.1158/0008-5472.CAN-19-2415. Epub 2020 May 14. PubMed |
| Chronic GPER1 Activation Protects Against Oxidative Stress-Induced Cardiomyoblast Death via Preservation of Mitochondrial Integrity and Deactivation of Mammalian Sterile-20-Like Kinase/Yes-Associated Protein Pathway. Imam Aliagan A, Madungwe NB, Tombo N, Feng Y, Bopassa JC. Front Endocrinol (Lausanne). 2020 Oct 19;11:579161. doi: 10.3389/fendo.2020.579161. eCollection 2020. PubMed |
| YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction. Mia MM, Cibi DM, Abdul Ghani SAB, Song W, Tee N, Ghosh S, Mao J, Olson EN, Singh MK. PLoS Biol. 2020 Dec 2;18(12):e3000941. doi: 10.1371/journal.pbio.3000941. eCollection 2020 Dec. PubMed |
| The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth. Morice S, Mullard M, Brion R, Dupuy M, Renault S, Tesfaye R, Brounais-Le Royer B, Ory B, Redini F, Verrecchia F. Cancers (Basel). 2020 Dec 20;12(12). pii: cancers12123847. doi: 10.3390/cancers12123847. PubMed |
| AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis. Francisco J, Zhang Y, Nakada Y, Jeong JI, Huang CY, Ivessa A, Oka S, Babu GJ, Del Re DP. Sci Rep. 2021 May 18;11(1):10553. doi: 10.1038/s41598-021-89989-5. PubMed |
| PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Muller cells during diabetic retinopathy. Guo Y, Cang X, Zhu L, Zhu M, Li A, Wang Z, Zhang Y, Wang X, Song E. Exp Eye Res. 2021 Sep;210:108703. doi: 10.1016/j.exer.2021.108703. Epub 2021 Jul 17. PubMed |
| YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1. Gokey JJ, Snowball J, Sridharan A, Sudha P, Kitzmiller JA, Xu Y, Whitsett JA. iScience. 2021 Aug 11;24(9):102967. doi: 10.1016/j.isci.2021.102967. eCollection 2021 Sep 24. PubMed |
| Involvement of the TGF-beta Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis. Morice S, Danieau G, Tesfaye R, Mullard M, Brion R, Dupuy M, Ory B, Brounais-Le Royer B, Corre I, Redini F, Verrecchia F. Front Oncol. 2021 Oct 26;11:765711. doi: 10.3389/fonc.2021.765711. eCollection 2021. PubMed |
| RhoA-ROCK competes with YAP to regulate amoeboid breast cancer cell migration in response to lymphatic-like flow. Mohammadalipour A, Diaz MF, Livingston M, Ewere A, Zhou A, Horton PD, Olamigoke LT, Lamar JM, Hagan JP, Lee HJ, Wenzel PL. FASEB Bioadv. 2022 Feb 14;4(5):342-361. doi: 10.1096/fba.2021-00055. eCollection 2022 May. PubMed |
| A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth. Ong YT, Andrade J, Armbruster M, Shi C, Castro M, Costa ASH, Sugino T, Eelen G, Zimmermann B, Wilhelm K, Lim J, Watanabe S, Guenther S, Schneider A, Zanconato F, Kaulich M, Pan D, Braun T, Gerhardt H, Efeyan A, Carmeliet P, Piccolo S, Grosso AR, Potente M. Nat Metab. 2022 Jun;4(6):672-682. doi: 10.1038/s42255-022-00584-y. Epub 2022 Jun 20. PubMed |
| C12orf59 Promotes Esophageal Squamous Cell Carcinoma Progression via YAP-Mediated Epithelial-Mesenchymal Transition. Xu C, Lin S, Lu Y, Mao L, Li S, Li Z. Front Oncol. 2022 Jul 4;12:927249. doi: 10.3389/fonc.2022.927249. eCollection 2022. PubMed |
| TROP2 Represents a Negative Prognostic Factor in Colorectal Adenocarcinoma and Its Expression Is Associated with Features of Epithelial-Mesenchymal Transition and Invasiveness. Svec J, Stastna M, Janeckova L, Hrckulak D, Vojtechova M, Onhajzer J, Kriz V, Galuskova K, Sloncova E, Kubovciak J, Pfeiferova L, Hrudka J, Matej R, Waldauf P, Havluj L, Kolar M, Korinek V. Cancers (Basel). 2022 Aug 26;14(17):4137. doi: 10.3390/cancers14174137. PubMed |
| Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress. Francisco J, Guan J, Zhang Y, Nakada Y, Mareedu S, Sung EA, Hu CM, Oka S, Zhai P, Sadoshima J, Del Re DP. J Mol Cell Cardiol. 2023 Aug;181:1-14. doi: 10.1016/j.yjmcc.2023.05.004. Epub 2023 May 24. PubMed |
| Genetic and Pharmacological YAP Activation Induces Proliferation and Improves Survival in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Bui TA, Stafford N, Oceandy D. Cells. 2023 Aug 22;12(17):2121. doi: 10.3390/cells12172121. PubMed |
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