pLKO1-shYAP2 Citations (14)
Originally described in: TEAD mediates YAP-dependent gene induction and growth control.Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL Genes Dev. 2008 Jul 15. 22(14):1962-71. PubMed Journal
Articles Citing pLKO1-shYAP2
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AMPK modulates Hippo pathway activity to regulate energy homeostasis. Wang W, Xiao ZD, Li X, Aziz KE, Gan B, Johnson RL, Chen J. Nat Cell Biol. 2015 Apr;17(4):490-9. doi: 10.1038/ncb3113. Epub 2015 Mar 9. PubMed |
A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma. Hiemer SE, Zhang L, Kartha VK, Packer TS, Almershed M, Noonan V, Kukuruzinska M, Bais MV, Monti S, Varelas X. Mol Cancer Res. 2015 Jun;13(6):957-68. doi: 10.1158/1541-7786.MCR-14-0580. Epub 2015 Mar 20. PubMed |
Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Chen YB, Xu J, Skanderup AJ, Dong Y, Brannon AR, Wang L, Won HH, Wang PI, Nanjangud GJ, Jungbluth AA, Li W, Ojeda V, Hakimi AA, Voss MH, Schultz N, Motzer RJ, Russo P, Cheng EH, Giancotti FG, Lee W, Berger MF, Tickoo SK, Reuter VE, Hsieh JJ. Nat Commun. 2016 Oct 7;7:13131. doi: 10.1038/ncomms13131. PubMed |
YAP1-TEAD1-Glut1 axis dictates the oncogenic phenotypes of breast cancer cells by modulating glycolysis. Lin C, Xu X. Biomed Pharmacother. 2017 Nov;95:789-794. doi: 10.1016/j.biopha.2017.08.091. Epub 2017 Sep 10. PubMed |
LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism. Zheng X, Han H, Liu GP, Ma YX, Pan RL, Sang LJ, Li RH, Yang LJ, Marks JR, Wang W, Lin A. EMBO J. 2017 Nov 15;36(22):3325-3335. doi: 10.15252/embj.201797609. Epub 2017 Sep 28. PubMed |
Novel YAP1 Activator, Identified by Transcription-Based Functional Screen, Limits Multiple Myeloma Growth.
Maruyama J, Inami K, Michishita F, Jiang X, Iwasa H, Nakagawa K, Ishigami-Yuasa M, Kagechika H, Miyamura N, Hirayama J, Nishina H, Nogawa D, Yamamoto K, Hata Y.
Mol Cancer Res. 2018 Feb;16(2):197-211. doi: 10.1158/1541-7786.MCR-17-0382. Epub 2017 Oct 23.
PubMed
Associated Plasmids |
Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner. Lee Y, Kim NH, Cho ES, Yang JH, Cha YH, Kang HE, Yun JS, Cho SB, Lee SH, Paclikova P, Radaszkiewicz TW, Bryja V, Kang CG, Yuk YS, Cha SY, Kim SY, Kim HS, Yook JI. Nat Commun. 2018 Jun 12;9(1):2301. doi: 10.1038/s41467-018-04757-w. PubMed |
Hippo signaling dysfunction induces cancer cell addiction to YAP. Han H, Yang B, Nakaoka HJ, Yang J, Zhao Y, Le Nguyen K, Bishara AT, Mandalia TK, Wang W. Oncogene. 2018 Dec;37(50):6414-6424. doi: 10.1038/s41388-018-0419-5. Epub 2018 Aug 1. PubMed |
Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers. Malouf GG, Flippot R, Dong Y, Dinatale RG, Chen YB, Su X, Comperat E, Roupret M, Mano R, Blum KA, Yao H, Mouawad R, Spano JP, Khayat D, Karam JA, Ho TH, Tickoo SK, Russo P, Hsieh JJ, Tannir NM, Hakimi AA. Sci Rep. 2020 Jan 20;10(1):701. doi: 10.1038/s41598-020-57534-5. PubMed |
MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation. Seo G, Han H, Vargas RE, Yang B, Li X, Wang W. Cell Rep. 2020 Jul 7;32(1):107860. doi: 10.1016/j.celrep.2020.107860. PubMed |
YAP promotes sorafenib resistance in hepatocellular carcinoma by upregulating survivin. Sun T, Mao W, Peng H, Wang Q, Jiao L. Cell Oncol (Dordr). 2021 Jun;44(3):689-699. doi: 10.1007/s13402-021-00595-z. Epub 2021 Mar 3. PubMed |
The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2. Yang WH, Lin CC, Wu J, Chao PY, Chen K, Chen PH, Chi JT. Mol Cancer Res. 2021 Jun;19(6):1005-1014. doi: 10.1158/1541-7786.MCR-20-0534. Epub 2021 Mar 11. PubMed |
Autophagy-mediated negative feedback attenuates the oncogenic activity of YAP in pancreatic cancer. Sun T, Peng H, Mao W, Ma L, Liu H, Mai J, Jiao L. Int J Biol Sci. 2021 Aug 21;17(13):3634-3645. doi: 10.7150/ijbs.61795. eCollection 2021. PubMed |
"Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2". Bulos ML, Grzelak EM, Li-Ma C, Chen E, Hull M, Johnson KA, Bollong MJ. bioRxiv. 2023 Apr 19:2023.04.19.537449. doi: 10.1101/2023.04.19.537449. Preprint. PubMed |
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