LeGO-C2 Citations (35)

Originally described in: A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis.
Weber K, Bartsch U, Stocking C, Fehse B Mol Ther. 2008 Apr . 16(4):698-706. PubMed Journal

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Articles Citing LeGO-C2

Articles
RGB marking with lentiviral vectors for multicolor clonal cell tracking. Weber K, Thomaschewski M, Benten D, Fehse B. Nat Protoc. 2012 Apr 5;7(5):839-49. doi: 10.1038/nprot.2012.026. PubMed
In vivo clonal tracking of hematopoietic stem and progenitor cells marked by five fluorescent proteins using confocal and multiphoton microscopy. Malide D, Metais JY, Dunbar CE. J Vis Exp. 2014 Aug 6;(90):e51669. doi: 10.3791/51669. PubMed
In-vivo RGB marking and multicolour single-cell tracking in the adult brain. Gomez-Nicola D, Riecken K, Fehse B, Perry VH. Sci Rep. 2014 Dec 22;4:7520. doi: 10.1038/srep07520. PubMed
Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering. Arulmoli J, Wright HJ, Phan DT, Sheth U, Que RA, Botten GA, Keating M, Botvinick EL, Pathak MM, Zarembinski TI, Yanni DS, Razorenova OV, Hughes CC, Flanagan LA. Acta Biomater. 2016 Oct 1;43:122-38. doi: 10.1016/j.actbio.2016.07.043. Epub 2016 Jul 27. PubMed
3D microtumors in vitro supported by perfused vascular networks. Sobrino A, Phan DT, Datta R, Wang X, Hachey SJ, Romero-Lopez M, Gratton E, Lee AP, George SC, Hughes CC. Sci Rep. 2016 Aug 23;6:31589. doi: 10.1038/srep31589. PubMed
Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Romero-Lopez M, Trinh AL, Sobrino A, Hatch MM, Keating MT, Fimbres C, Lewis DE, Gershon PD, Botvinick EL, Digman M, Lowengrub JS, Hughes CC. Biomaterials. 2017 Feb;116:118-129. doi: 10.1016/j.biomaterials.2016.11.034. Epub 2016 Nov 24. PubMed
Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition. Ebbing EA, Steins A, Fessler E, Stathi P, Lesterhuis WJ, Krishnadath KK, Vermeulen L, Medema JP, Bijlsma MF, van Laarhoven HWM. Gastroenterology. 2017 Jul;153(1):63-76.e14. doi: 10.1053/j.gastro.2017.03.004. Epub 2017 Mar 9. PubMed
Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model. Thomaschewski M, Riecken K, Unrau L, Volz T, Cornils K, Ittrich H, Heim D, Wege H, Akgun E, Lutgehetmann M, Dieckhoff J, Kopke M, Dandri M, Benten D, Fehse B. Oncotarget. 2017 Dec 14;8(70):115582-115595. doi: 10.18632/oncotarget.23312. eCollection 2017 Dec 29. PubMed
Clonal dynamics in osteosarcoma defined by RGB marking. Gambera S, Abarrategi A, Gonzalez-Camacho F, Morales-Molina A, Roma J, Alfranca A, Garcia-Castro J. Nat Commun. 2018 Sep 28;9(1):3994. doi: 10.1038/s41467-018-06401-z. PubMed
Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma. Roh V, Abramowski P, Hiou-Feige A, Cornils K, Rivals JP, Zougman A, Aranyossy T, Thielecke L, Truan Z, Mermod M, Monnier Y, Prassolov V, Glauche I, Nowrouzi A, Abdollahi A, Fehse B, Simon C, Tolstonog GV. Cell Rep. 2018 Nov 20;25(8):2208-2222.e7. doi: 10.1016/j.celrep.2018.10.090. PubMed
Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts. van der Heijden M, Miedema DM, Waclaw B, Veenstra VL, Lecca MC, Nijman LE, van Dijk E, van Neerven SM, Lodestijn SC, Lenos KJ, de Groot NE, Prasetyanti PR, Arricibita Varea A, Winton DJ, Medema JP, Morrissey E, Ylstra B, Nowak MA, Bijlsma MF, Vermeulen L. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6140-6145. doi: 10.1073/pnas.1813417116. Epub 2019 Mar 8. PubMed
The transcription factor FOXM1 regulates the balance between proliferation and aberrant differentiation in head and neck squamous cell carcinoma. Roh V, Hiou-Feige A, Misetic V, Rivals JP, Sponarova J, Teh MT, Ferreira Lopes S, Truan Z, Mermod M, Monnier Y, Hess J, Tolstonog GV, Simon C. J Pathol. 2020 Jan;250(1):107-119. doi: 10.1002/path.5342. Epub 2019 Dec 3. PubMed
Quantification of the dynamics of population heterogeneities in CHO cultures with stably integrated fluorescent markers. Moller J, Rosenberg M, Riecken K, Portner R, Zeng AP, Jandt U. Anal Bioanal Chem. 2020 Apr;412(9):2065-2080. doi: 10.1007/s00216-020-02401-5. Epub 2020 Mar 4. PubMed
High-grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF-1. Steins A, van Mackelenbergh MG, van der Zalm AP, Klaassen R, Serrels B, Goris SG, Kocher HM, Waasdorp C, de Jong JH, Tekin C, Besselink MG, Busch OR, van de Vijver MJ, Verheij J, Dijk F, van Tienhoven G, Wilmink JW, Medema JP, van Laarhoven HW, Bijlsma MF. EMBO Rep. 2020 May 6;21(5):e48780. doi: 10.15252/embr.201948780. Epub 2020 Mar 16. PubMed
Exploiting collateral sensitivity controls growth of mixed culture of sensitive and resistant cells and decreases selection for resistant cells in a cell line model. Grolmusz VK, Chen J, Emond R, Cosgrove PA, Pflieger L, Nath A, Moos PJ, Bild AH. Cancer Cell Int. 2020 Jun 17;20:253. doi: 10.1186/s12935-020-01337-1. eCollection 2020. PubMed
Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs. Liu Y, Sakolish C, Chen Z, Phan DTT, Bender RHF, Hughes CCW, Rusyn I. Toxicology. 2020 Dec 1;445:152601. doi: 10.1016/j.tox.2020.152601. Epub 2020 Sep 24. PubMed
Soluble Compounds Released by Hypoxic Stroma Confer Invasive Properties to Pancreatic Ductal Adenocarcinoma. Liu D, Steins A, Klaassen R, van der Zalm AP, Bennink RJ, van Tienhoven G, Besselink MG, Bijlsma MF, van Laarhoven HWM. Biomedicines. 2020 Oct 22;8(11). pii: biomedicines8110444. doi: 10.3390/biomedicines8110444. PubMed
An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy. Hachey SJ, Movsesyan S, Nguyen QH, Burton-Sojo G, Tankazyan A, Wu J, Hoang T, Zhao D, Wang S, Hatch MM, Celaya E, Gomez S, Chen GT, Davis RT, Nee K, Pervolarakis N, Lawson DA, Kessenbrock K, Lee AP, Lowengrub J, Waterman ML, Hughes CCW. Lab Chip. 2021 Apr 7;21(7):1333-1351. doi: 10.1039/d0lc01216e. Epub 2021 Feb 19. PubMed
RGB-Marking to Identify Patterns of Selection and Neutral Evolution in Human Osteosarcoma Models. Gambera S, Patino-Garcia A, Alfranca A, Garcia-Castro J. Cancers (Basel). 2021 Apr 21;13(9). pii: cancers13092003. doi: 10.3390/cancers13092003. PubMed
A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma. Gonzalez Rajal A, Marzec KA, McCloy RA, Nobis M, Chin V, Hastings JF, Lai K, Kennerson M, Hughes WE, Vaghjiani V, Timpson P, Cain JE, Watkins DN, Croucher DR, Burgess A. Elife. 2021 May 13;10:e65234. doi: 10.7554/eLife.65234. PubMed
Tepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1. McQuerry JA, Chen J, Chang JT, Bild AH. Transl Oncol. 2021 Oct;14(10):101181. doi: 10.1016/j.tranon.2021.101181. Epub 2021 Jul 20. PubMed
Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment. Ring SS, Cupovic J, Onder L, Lutge M, Perez-Shibayama C, Gil-Cruz C, Scandella E, De Martin A, Morbe U, Hartmann F, Wenger R, Spiegl M, Besse A, Bonilla WV, Stemeseder F, Schmidt S, Orlinger KK, Krebs P, Ludewig B, Flatz L. Nat Commun. 2021 Aug 5;12(1):4734. doi: 10.1038/s41467-021-25057-w. PubMed
Phenotypic Consequences of SLC25A40-ABCB1 Fusions beyond Drug Resistance in High-Grade Serous Ovarian Cancer. Pishas KI, Cowley KJ, Pandey A, Hoang T, Beach JA, Luu J, Vary R, Smith LK, Shembrey CE, Rashoo N, White MO, Simpson KJ, Bild A, Griffiths JI, Cheasley D, Campbell I, Bowtell DDL, Christie EL. Cancers (Basel). 2021 Nov 11;13(22). pii: cancers13225644. doi: 10.3390/cancers13225644. PubMed
Pulpbow: A Method to Study the Vasculogenic Potential of Mesenchymal Stem Cells from the Dental Pulp. Mantesso A, Zhang Z, Warner KA, Herzog AE, Pulianmackal AJ, Nor JE. Cells. 2021 Oct 20;10(11). pii: cells10112804. doi: 10.3390/cells10112804. PubMed
Intestinal organoid co-culture protocol to study cell competition in vitro. van Neerven SM, Ramadan R, van Driel MS, Huels DJ, Vermeulen L. STAR Protoc. 2021 Dec 16;3(1):101050. doi: 10.1016/j.xpro.2021.101050. eCollection 2022 Mar 18. PubMed
Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy. Paasch D, Meyer J, Stamopoulou A, Lenz D, Kuehle J, Kloos D, Buchegger T, Holzinger A, Falk CS, Kloth C, von Kaisenberg CS, Abken H, Schambach A, Lachmann N, Morgan M, Moritz T. Cells. 2022 Mar 15;11(6). pii: cells11060994. doi: 10.3390/cells11060994. PubMed
Cellular Heterogeneity and Cooperativity in Glioma Persister Cells Under Temozolomide Treatment. Rabe M, Fonteneau L, Oliver L, Morales-Molina A, Jubelin C, Garcia-Castro J, Heymann D, Gratas C, Vallette FM. Front Cell Dev Biol. 2022 May 25;10:835273. doi: 10.3389/fcell.2022.835273. eCollection 2022. PubMed
A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease. Hachey SJ, Sobrino A, Lee JG, Jafari MD, Klempner SJ, Puttock EJ, Edwards RA, Lowengrub JS, Waterman ML, Zell JA, Hughes CCW. Transl Res. 2023 May;255:97-108. doi: 10.1016/j.trsl.2022.11.011. Epub 2022 Dec 5. PubMed
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22. Giannou AD, Kempski J, Shiri AM, Lucke J, Zhang T, Zhao L, Zazara DE, Cortesi F, Riecken K, Amezcua Vesely MC, Low JS, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens KF, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Bottcher M, Sabihi M, Huber FJ, Reeh M, Grass JK, Wahib R, Seese H, Stuben BO, Fard-Aghaie M, Dupree A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis IC, Arck PC, Perez D, Gao B, Zarogiannis SG, Strowig T, Pasqualini R, Arap W, Gosalvez JS, Kobold S, Prinz I, Guse AH, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki JR, Pantel K, Schumacher U, Lohse AW, Flavell RA, Gagliani N, Huber S. Immunity. 2023 Jan 10;56(1):125-142.e12. doi: 10.1016/j.immuni.2022.12.014. PubMed
Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling. Barry-Carroll L, Greulich P, Marshall AR, Riecken K, Fehse B, Askew KE, Li K, Garaschuk O, Menassa DA, Gomez-Nicola D. Cell Rep. 2023 May 30;42(5):112425. doi: 10.1016/j.celrep.2023.112425. Epub 2023 Apr 25. PubMed
ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer. Farmaki E, Nath A, Emond R, Karimi KL, Grolmusz VK, Cosgrove PA, Bild AH. Elife. 2023 Sep 29;12:e85898. doi: 10.7554/eLife.85898. PubMed
High-Content and High-Throughput Clonogenic Survival Assay Using Fluorescence Barcoding. Qian H, Baglamis S, Redeker F, Raaijman J, Hoebe RA, Sheraton VM, Vermeulen L, Krawczyk PM. Cancers (Basel). 2023 Sep 28;15(19):4772. doi: 10.3390/cancers15194772. PubMed
Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures. Baglamis S, Sheraton VM, Meijer D, Qian H, Hoebe RA, Lenos KJ, Betjes MA, Betjes MA, Tans S, van Zon J, Vermeulen L, Krawczyk PM. Sci Rep. 2023 Nov 1;13(1):18832. doi: 10.1038/s41598-023-42849-w. PubMed
Endothelial Cell Replacement of Human Veins, Modeling Vascular Repair and Endothelial Cell Chimerism. Tejeda-Mora H, den Hartog Y, Schurink IJ, Verstegen MMA, de Jonge J, van den Hoogen MWF, Baan CC, Minnee RC, Hoogduijn MJ, van der Laan LJW, Willemse J. Stem Cells Dev. 2024 Jan;33(1-2):27-42. doi: 10.1089/scd.2023.0142. Epub 2023 Dec 27. PubMed
Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia. Abdin SM, Paasch D, Kloos A, Oliveira MC, Jang MS, Ackermann M, Stamopoulou A, Mroch PJ, Falk CS, von Kaisenberg CS, Schambach A, Heuser M, Moritz T, Hansen G, Morgan M, Lachmann N. J Immunother Cancer. 2023 Dec 22;11(12):e007705. doi: 10.1136/jitc-2023-007705. PubMed

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