pCI HA NEDD4L Citations (10)

Originally described in: Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.
Gao S, Alarcon C, Sapkota G, Rahman S, Chen PY, Goerner N, Macias MJ, Erdjument-Bromage H, Tempst P, Massague J Mol Cell. 2009 Nov 13. 36(3):457-68. PubMed Journal

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Articles Citing pCI HA NEDD4L

Articles
NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling. Tanksley JP, Chen X, Coffey RJ. PLoS One. 2013 Nov 28;8(11):e81514. doi: 10.1371/journal.pone.0081514. eCollection 2013. PubMed
Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, Malumbres M, Liu J, Zou W, Wei W. Cell Discov. 2016 Feb 2;2:15044. doi: 10.1038/celldisc.2015.44. eCollection 2016. PubMed
Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of beta-ENaC in a Human Alveolar Epithelial Cell Line. Gwozdzinska P, Buchbinder BA, Mayer K, Herold S, Morty RE, Seeger W, Vadasz I. Front Immunol. 2017 May 23;8:591. doi: 10.3389/fimmu.2017.00591. eCollection 2017. PubMed
Sculpting ion channel functional expression with engineered ubiquitin ligases. Kanner SA, Morgenstern T, Colecraft HM. Elife. 2017 Dec 19;6. pii: 29744. doi: 10.7554/eLife.29744. PubMed
The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L. Guarnieri AL, Towers CG, Drasin DJ, Oliphant MUJ, Andrysik Z, Hotz TJ, Vartuli RL, Linklater ES, Pandey A, Khanal S, Espinosa JM, Ford HL. Oncogene. 2018 Jul;37(28):3879-3893. doi: 10.1038/s41388-018-0239-7. Epub 2018 Apr 17. PubMed
A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVbeta subunits. Morgenstern TJ, Park J, Fan QR, Colecraft HM. Elife. 2019 Aug 12;8. pii: 49253. doi: 10.7554/eLife.49253. PubMed
Metabolic engineering of HEK293 cells to improve transient transfection and cell budding of HIV-1 virus-like particles. Lavado-Garcia J, Diaz-Maneh A, Canal-Pauli N, Perez-Rubio P, Godia F, Cervera L. Biotechnol Bioeng. 2021 Apr;118(4):1649-1663. doi: 10.1002/bit.27679. Epub 2021 Jan 25. PubMed
SPLUNC1 is a negative regulator of the Orai1 Ca(2+) channel. Wu T, Goriounova AS, Worthington EN, Wrennall JA, Ghosh A, Ahmad S, Flori Sassano M, Tarran R. Physiol Rep. 2022 May;10(10):e15306. doi: 10.14814/phy2.15306. PubMed
Modulating Endoplasmic Reticulum Chaperones and Mutant Protein Degradation in GABRG2(Q390X) Associated with Genetic Epilepsy with Febrile Seizures Plus and Dravet Syndrome. Poliquin S, Nwosu G, Randhave K, Shen W, Flamm C, Kang JQ. Int J Mol Sci. 2024 Apr 23;25(9):4601. doi: 10.3390/ijms25094601. PubMed
Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies. Morgenstern TJ, Darko-Boateng A, Afriyie E, Shanmugam SK, Zhou X, Choudhury P, Desai M, Kass RS, Clarke OB, Colecraft HM. bioRxiv [Preprint]. 2024 May 31:2024.05.28.596281. doi: 10.1101/2024.05.28.596281. PubMed

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