pBABE-Src-Dasatinib-resistant Citations (6)
Originally described in: Latent bone metastasis in breast cancer tied to Src-dependent survival signals.Zhang XH, Wang Q, Gerald W, Hudis CA, Norton L, Smid M, Foekens JA, Massague J Cancer Cell. 2009 Jul 7. 16(1):67-78. PubMed Journal
Articles Citing pBABE-Src-Dasatinib-resistant
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Targeted inhibition of Src kinase with dasatinib blocks thyroid cancer growth and metastasis. Chan CM, Jing X, Pike LA, Zhou Q, Lim DJ, Sams SB, Lund GS, Sharma V, Haugen BR, Schweppe RE. Clin Cancer Res. 2012 Jul 1;18(13):3580-91. doi: 10.1158/1078-0432.CCR-11-3359. Epub 2012 May 14. PubMed |
Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth. Yeung CL, Ngo VN, Grohar PJ, Arnaldez FI, Asante A, Wan X, Khan J, Hewitt SM, Khanna C, Staudt LM, Helman LJ. Oncogene. 2013 Nov 21;32(47):5429-38. doi: 10.1038/onc.2012.590. Epub 2013 Jan 14. PubMed |
Src-mediated regulation of the PI3K pathway in advanced papillary and anaplastic thyroid cancer. Beadnell TC, Nassar KW, Rose MM, Clark EG, Danysh BP, Hofmann MC, Pozdeyev N, Schweppe RE. Oncogenesis. 2018 Feb 28;7(2):23. doi: 10.1038/s41389-017-0015-5. PubMed |
Resistance to Src inhibition alters the BRAF-mutant tumor secretome to promote an invasive phenotype and therapeutic escape through a FAK>p130Cas>c-Jun signaling axis. Kessler BE, Mishall KM, Kellett MD, Clark EG, Pugazhenthi U, Pozdeyev N, Kim J, Tan AC, Schweppe RE. Oncogene. 2019 Apr;38(14):2565-2579. doi: 10.1038/s41388-018-0617-1. Epub 2018 Dec 10. PubMed |
Targeting the Src Pathway Enhances the Efficacy of Selective FGFR Inhibitors in Urothelial Cancers with FGFR3 Alterations. Lima NC, Atkinson E, Bunney TD, Katan M, Huang PH. Int J Mol Sci. 2020 May 1;21(9). pii: ijms21093214. doi: 10.3390/ijms21093214. PubMed |
Dasatinib targets c-Src kinase in cardiotoxicity. Elmadani M, Raatikainen S, Mattila O, Alakoski T, Piuhola J, Astrom P, Tenhunen O, Magga J, Kerkela R. Toxicol Rep. 2023 Apr 25;10:521-528. doi: 10.1016/j.toxrep.2023.04.013. eCollection 2023. PubMed |
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