deltaNp63alpha-FLAG Citations (23)
Originally described in: U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha.Chatterjee A, Upadhyay S, Chang X, Nagpal JK, Trink B, Sidransky D Cell Cycle. 2008 May 1. 7(9):1231-7. PubMed Journal
Articles Citing deltaNp63alpha-FLAG
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| DeltaNp63 promotes pediatric neuroblastoma and osteosarcoma by regulating tumor angiogenesis. Bid HK, Roberts RD, Cam M, Audino A, Kurmasheva RT, Lin J, Houghton PJ, Cam H. Cancer Res. 2014 Jan 1;74(1):320-9. doi: 10.1158/0008-5472.CAN-13-0894. Epub 2013 Oct 23. PubMed |
| S100A6 expression in keratinocytes and its impact on epidermal differentiation. Graczyk A, Lesniak W. Int J Biochem Cell Biol. 2014 Dec;57:135-41. doi: 10.1016/j.biocel.2014.10.007. Epub 2014 Oct 14. PubMed |
| MicroRNA-200c-141 and Np63 are required for breast epithelial differentiation and branching morphogenesis. Hilmarsdottir B, Briem E, Sigurdsson V, Franzdottir SR, Ringner M, Arason AJ, Bergthorsson JT, Magnusson MK, Gudjonsson T. Dev Biol. 2015 Jul 15;403(2):150-61. doi: 10.1016/j.ydbio.2015.05.007. Epub 2015 May 9. PubMed |
| DeltaNp63alpha Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion. Yang K, Wu WM, Chen YC, Lo SH, Liao YC. PLoS One. 2016 Jan 19;11(1):e0147542. doi: 10.1371/journal.pone.0147542. eCollection 2016. PubMed |
| DeltaNp63 mediates cellular survival and metastasis in canine osteosarcoma. Cam M, Gardner HL, Roberts RD, Fenger JM, Guttridge DC, London CA, Cam H. Oncotarget. 2016 Jul 26;7(30):48533-48546. doi: 10.18632/oncotarget.10406. PubMed |
| DeltaNp63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis. Di Franco S, Turdo A, Benfante A, Colorito ML, Gaggianesi M, Apuzzo T, Kandimalla R, Chinnici A, Barcaroli D, Mangiapane LR, Pistone G, Vieni S, Gulotta E, Dieli F, Medema JP, Stassi G, De Laurenzi V, Todaro M. Oncotarget. 2016 Aug 23;7(34):54157-54173. doi: 10.18632/oncotarget.11022. PubMed |
| Expression of p63 protein in anaplastic large cell lymphoma: implications for genetic subtyping. Wang X, Boddicker RL, Dasari S, Sidhu JS, Kadin ME, Macon WR, Ansell SM, Ketterling RP, Rech KL, Feldman AL. Hum Pathol. 2017 Jun;64:19-27. doi: 10.1016/j.humpath.2017.01.003. Epub 2017 Jan 30. PubMed |
| Hepatic p63 regulates steatosis via IKKbeta/ER stress. Porteiro B, Fondevila MF, Delgado TC, Iglesias C, Imbernon M, Iruzubieta P, Crespo J, Zabala-Letona A, Ferno J, Gonzalez-Teran B, Matesanz N, Hernandez-Cosido L, Marcos M, Tovar S, Vidal A, Sanchez-Ceinos J, Malagon MM, Pombo C, Zalvide J, Carracedo A, Buque X, Dieguez C, Sabio G, Lopez M, Aspichueta P, Martinez-Chantar ML, Nogueiras R. Nat Commun. 2017 May 8;8:15111. doi: 10.1038/ncomms15111. PubMed |
| KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis. Lin-Shiao E, Lan Y, Coradin M, Anderson A, Donahue G, Simpson CL, Sen P, Saffie R, Busino L, Garcia BA, Berger SL, Capell BC. Genes Dev. 2018 Jan 15;32(2):181-193. doi: 10.1101/gad.306241.117. Epub 2018 Feb 12. PubMed |
| Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression. Jiang Y, Jiang YY, Xie JJ, Mayakonda A, Hazawa M, Chen L, Xiao JF, Li CQ, Huang ML, Ding LW, Sun QY, Xu L, Kanojia D, Jeitany M, Deng JW, Liao LD, Soukiasian HJ, Berman BP, Hao JJ, Xu LY, Li EM, Wang MR, Bi XG, Lin DC, Koeffler HP. Nat Commun. 2018 Sep 6;9(1):3619. doi: 10.1038/s41467-018-06081-9. PubMed |
| TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma. Somerville TDD, Xu Y, Miyabayashi K, Tiriac H, Cleary CR, Maia-Silva D, Milazzo JP, Tuveson DA, Vakoc CR. Cell Rep. 2018 Nov 13;25(7):1741-1755.e7. doi: 10.1016/j.celrep.2018.10.051. PubMed |
| Metformin and 4SC-202 synergistically promote intrinsic cell apoptosis by accelerating DeltaNp63 ubiquitination and degradation in oral squamous cell carcinoma. He Y, Tai S, Deng M, Fan Z, Ping F, He L, Zhang C, Huang Y, Cheng B, Xia J. Cancer Med. 2019 Jul;8(7):3479-3490. doi: 10.1002/cam4.2206. Epub 2019 Apr 25. PubMed |
| p63 establishes epithelial enhancers at critical craniofacial development genes. Lin-Shiao E, Lan Y, Welzenbach J, Alexander KA, Zhang Z, Knapp M, Mangold E, Sammons M, Ludwig KU, Berger SL. Sci Adv. 2019 May 1;5(5):eaaw0946. doi: 10.1126/sciadv.aaw0946. eCollection 2019 May. PubMed |
| Shp2-mediated MAPK pathway regulates DeltaNp63 in epithelium to promote corneal innervation and homeostasis. Okada Y, Zhang Y, Zhang L, Yeh LK, Wang YC, Saika S, Liu CY. Lab Invest. 2019 Oct 25. pii: 10.1038/s41374-019-0338-2. doi: 10.1038/s41374-019-0338-2. PubMed |
| Long-term expansion of directly reprogrammed keratinocyte-like cells and in vitro reconstitution of human skin. Zheng J, Yun W, Park J, Kang PJ, Lee G, Song G, Kim IY, You S. J Biomed Sci. 2020 Apr 20;27(1):56. doi: 10.1186/s12929-020-00642-1. PubMed |
| DeltaNp63 regulated epithelial-to-mesenchymal transition state heterogeneity confers a leader-follower relationship that drives collective invasion. Westcott JM, Camacho S, Nasir A, Huysman ME, Rahhal R, Dang TT, Riegel AT, Brekken RA, Pearson GW. Cancer Res. 2020 Jul 13. pii: 0008-5472.CAN-20-0014. doi: 10.1158/0008-5472.CAN-20-0014. PubMed |
| BRD4 Regulates Transcription Factor DeltaNp63alpha to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas. Fisher ML, Balinth S, Hwangbo Y, Wu C, Ballon C, Wilkinson JE, Goldberg GL, Mills AA. Cancer Res. 2021 Dec 15;81(24):6246-6258. doi: 10.1158/0008-5472.CAN-21-0707. Epub 2021 Oct 25. PubMed |
| DeltaNp63alpha promotes Epstein-Barr virus latency in undifferentiated epithelial cells. Van Sciver N, Ohashi M, Nawandar DM, Pauly NP, Lee D, Makielski KR, Bristol JA, Tsao SW, Lambert PF, Johannsen EC, Kenney SC. PLoS Pathog. 2021 Nov 8;17(11):e1010045. doi: 10.1371/journal.ppat.1010045. eCollection 2021 Nov. PubMed |
| p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation. Pinnamaneni JP, Singh VP, Kim MB, Ryan CT, Pugazenthi A, Sanagasetti D, Mathison M, Yang J, Rosengart TK. Sci Rep. 2022 Jul 6;12(1):11416. doi: 10.1038/s41598-022-15559-y. PubMed |
Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation.
Sasamoto Y, Lee CAA, Wilson BJ, Buerger F, Martin G, Mishra A, Kiritoshi S, Tran J, Gonzalez G, Hildebrandt F, Jo VY, Lian CG, Murphy GF, Ksander BR, Frank MH, Frank NY.
Cell Rep. 2022 Aug 9;40(6):111166. doi: 10.1016/j.celrep.2022.111166.
PubMed
Associated Plasmids |
| Cancer-associated fibroblasts promote cancer stemness by inducing expression of the chromatin-modifying protein CBX4 in squamous cell carcinoma. Fisher ML, Balinth S, Hwangbo Y, Wu C, Ballon C, Goldberg GL, Mills AA. Carcinogenesis. 2023 Aug 18;44(6):485-496. doi: 10.1093/carcin/bgad048. PubMed |
| TP63-TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer. Sultanov R, Mulyukina A, Zubkova O, Fedoseeva A, Bogomazova A, Klimina K, Larin A, Zatsepin T, Prikazchikova T, Lukina M, Bogomiakova M, Sharova E, Generozov E, Lagarkova M, Arapidi G. Epigenetics Chromatin. 2024 Mar 14;17(1):6. doi: 10.1186/s13072-024-00529-7. PubMed |
| Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-gamma signaling in squamous cancer. Jiang Y, Zheng Y, Zhang YW, Kong S, Dong J, Wang F, Ziman B, Gery S, Hao JJ, Zhou D, Zhou J, Ho AS, Sinha UK, Chen J, Zhang S, Yin C, Wei DD, Hazawa M, Pan H, Lu Z, Wei WQ, Wang MR, Koeffler HP, Lin DC, Jiang YY. Nat Commun. 2024 Mar 20;15(1):2484. doi: 10.1038/s41467-024-46785-9. PubMed |
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