pcDNA3.1-2xFLAG-SREBP-1c Citations (15)

Originally described in: Selective coactivator interactions in gene activation by SREBP-1a and -1c.
Toth JI, Datta S, Athanikar JN, Freedman LP, Osborne TF Mol Cell Biol. 2004 Sep . 24(18):8288-300. PubMed Journal

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Articles Citing pcDNA3.1-2xFLAG-SREBP-1c

Articles
Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation. Cermenati G, Abbiati F, Cermenati S, Brioschi E, Volonterio A, Cavaletti G, Saez E, De Fabiani E, Crestani M, Garcia-Segura LM, Melcangi RC, Caruso D, Mitro N. J Lipid Res. 2012 Feb;53(2):300-10. doi: 10.1194/jlr.M021188. Epub 2011 Dec 7. PubMed
Differential regulation of gene expression by LXRs in response to macrophage cholesterol loading. Ignatova ID, Angdisen J, Moran E, Schulman IG. Mol Endocrinol. 2013 Jul;27(7):1036-47. doi: 10.1210/me.2013-1051. Epub 2013 May 17. PubMed
Coordinated regulation of protein synthesis and degradation by mTORC1. Zhang Y, Nicholatos J, Dreier JR, Ricoult SJ, Widenmaier SB, Hotamisligil GS, Kwiatkowski DJ, Manning BD. Nature. 2014 Sep 18;513(7518):440-3. doi: 10.1038/nature13492. Epub 2014 Jul 13. PubMed
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth. Ru P, Hu P, Geng F, Mo X, Cheng C, Yoo JY, Cheng X, Wu X, Guo JY, Nakano I, Lefai E, Kaur B, Chakravarti A, Guo D. Cell Rep. 2016 Aug 9;16(6):1527-35. doi: 10.1016/j.celrep.2016.07.017. Epub 2016 Jul 28. PubMed
Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation. Zheng ZG, Zhou YP, Zhang X, Thu PM, Xie ZS, Lu C, Pang T, Xue B, Xu DQ, Chen Y, Chen XW, Li HJ, Xu X. Biochem Pharmacol. 2016 Dec 15;122:42-61. doi: 10.1016/j.bcp.2016.10.016. Epub 2016 Nov 2. PubMed
PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c. Pan G, Ameur A, Enroth S, Bysani M, Nord H, Cavalli M, Essand M, Gyllensten U, Wadelius C. Nucleic Acids Res. 2016 Dec 8. pii: gkw1186. PubMed
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth. Ru P, Hu P, Geng F, Mo X, Cheng C, Yoo JY, Cheng X, Wu X, Guo JY, Nakano I, Lefai E, Kaur B, Chakravarti A, Guo D. Cell Rep. 2017 Jan 24;18(4):1076-1077. doi: 10.1016/j.celrep.2017.01.016. PubMed
Opposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1. Posada IMD, Lectez B, Siddiqui FA, Oetken-Lindholm C, Sharma M, Abankwa D. Sci Rep. 2017 Aug 21;7(1):8944. doi: 10.1038/s41598-017-09387-8. PubMed
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1. Feng YX, Jin DX, Sokol ES, Reinhardt F, Miller DH, Gupta PB. Nat Commun. 2017 Oct 20;8(1):1079. doi: 10.1038/s41467-017-01052-y. PubMed
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. Nat Commun. 2019 Jan 10;10(1):120. doi: 10.1038/s41467-018-08015-x. PubMed
SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. Wu S, Naar AM. Sci Rep. 2019 Jul 17;9(1):10369. doi: 10.1038/s41598-019-46594-x. PubMed
Metabolic regulation of hepatic PNPLA3 expression and severity of liver fibrosis in patients with NASH. Bruschi FV, Tardelli M, Herac M, Claudel T, Trauner M. Liver Int. 2020 May;40(5):1098-1110. doi: 10.1111/liv.14402. Epub 2020 Mar 1. PubMed
ZHX2 inhibits SREBP1c-mediated de novo lipogenesis in hepatocellular carcinoma via miR-24-3p. Yu X, Lin Q, Wu Z, Zhang Y, Wang T, Zhao S, Song X, Chen C, Wang Z, Xu L, Li C, Gao L, Liang X, Yue X, Ma C. J Pathol. 2020 Dec;252(4):358-370. doi: 10.1002/path.5530. Epub 2020 Sep 14. PubMed
High throughput compound screening in neuronal cells identifies statins as activators of ataxin 3 expression. Stahl F, Schmitt I, Denner P, de Boni L, Wullner U, Breuer P. Sci Rep. 2023 Sep 9;13(1):14911. doi: 10.1038/s41598-023-41192-4. PubMed
Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators. Nikolaou KC, Godbersen S, Manoharan M, Wieland S, Heim MH, Stoffel M. JCI Insight. 2023 Nov 8;8(21):e164694. doi: 10.1172/jci.insight.164694. PubMed

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