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pcDNA3.1-2xFLAG-SREBP-1a Citations (12)

Originally described in: Selective coactivator interactions in gene activation by SREBP-1a and -1c.
Toth JI, Datta S, Athanikar JN, Freedman LP, Osborne TF Mol Cell Biol. 2004 Sep . 24(18):8288-300.
PubMed Journal

Articles Citing pcDNA3.1-2xFLAG-SREBP-1a

Articles
Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation. Cermenati G, Abbiati F, Cermenati S, Brioschi E, Volonterio A, Cavaletti G, Saez E, De Fabiani E, Crestani M, Garcia-Segura LM, Melcangi RC, Caruso D, Mitro N. J Lipid Res. 2012 Feb;53(2):300-10. doi: 10.1194/jlr.M021188. Epub 2011 Dec 7. PubMed
PKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection. Yu Y, Pierciey FJ Jr, Maguire TG, Alwine JC. PLoS Pathog. 2013;9(4):e1003266. doi: 10.1371/journal.ppat.1003266. Epub 2013 Apr 4. PubMed
Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). Madsen A, Bozickovic O, Bjune JI, Mellgren G, Sagen JV. Sci Rep. 2015 Nov 9;5:16430. doi: 10.1038/srep16430. PubMed
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth. Ru P, Hu P, Geng F, Mo X, Cheng C, Yoo JY, Cheng X, Wu X, Guo JY, Nakano I, Lefai E, Kaur B, Chakravarti A, Guo D. Cell Rep. 2016 Aug 9;16(6):1527-35. doi: 10.1016/j.celrep.2016.07.017. Epub 2016 Jul 28. PubMed
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth. Ru P, Hu P, Geng F, Mo X, Cheng C, Yoo JY, Cheng X, Wu X, Guo JY, Nakano I, Lefai E, Kaur B, Chakravarti A, Guo D. Cell Rep. 2017 Jan 24;18(4):1076-1077. doi: 10.1016/j.celrep.2017.01.016. PubMed
SREBP-2-driven transcriptional activation of human SND1 oncogene. Armengol S, Arretxe E, Enzunza L, Llorente I, Mendibil U, Navarro-Imaz H, Ochoa B, Chico Y, Martinez MJ. Oncotarget. 2017 Nov 21;8(64):108181-108194. doi: 10.18632/oncotarget.22569. eCollection 2017 Dec 8. PubMed
SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. Wu S, Naar AM. Sci Rep. 2019 Jul 17;9(1):10369. doi: 10.1038/s41598-019-46594-x. PubMed
Protein Arginine Methyltransferase PRMT5 Regulates Fatty Acid Metabolism and Lipid Droplet Biogenesis in White Adipose Tissues. Jia Z, Yue F, Chen X, Narayanan N, Qiu J, Syed SA, Imbalzano AN, Deng M, Yu P, Hu C, Kuang S. Adv Sci (Weinh). 2020 Oct 16;7(23):2002602. doi: 10.1002/advs.202002602. eCollection 2020 Dec. PubMed
Novel cholesterol-dependent regulation of cardiac KATP subunit expression revealed using histone deacetylase inhibitors. Geiger R, Fatima N, Schooley JF Jr, Smyth JT, Haigney MC, Flagg TP. Physiol Rep. 2021 Jan;8(24):e14675. doi: 10.14814/phy2.14675. PubMed
NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes. Kutchukian C, Vivas O, Casas M, Jones JG, Tiscione SA, Simo S, Ory DS, Dixon RE, Dickson EJ. EMBO J. 2021 Jul 1;40(13):e105990. doi: 10.15252/embj.2020105990. Epub 2021 May 21. PubMed
SREBP1 regulates Lgals3 activation in response to cholesterol loading. Li J, Shen H, Owens GK, Guo LW. Mol Ther Nucleic Acids. 2022 May 18;28:892-909. doi: 10.1016/j.omtn.2022.05.028. eCollection 2022 Jun 14. PubMed
High throughput compound screening in neuronal cells identifies statins as activators of ataxin 3 expression. Stahl F, Schmitt I, Denner P, de Boni L, Wullner U, Breuer P. Sci Rep. 2023 Sep 9;13(1):14911. doi: 10.1038/s41598-023-41192-4. PubMed

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