pRK-ATF4 Citations (17)

Originally described in: ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells.
Wang Q, Mora-Jensen H, Weniger MA, Perez-Galan P, Wolford C, Hai T, Ron D, Chen W, Trenkle W, Wiestner A, Ye Y Proc Natl Acad Sci U S A. 2009 Feb 17. 106(7):2200-5. PubMed Journal

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Articles Citing pRK-ATF4

Articles
Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation. De Sousa-Coelho AL, Marrero PF, Haro D. Biochem J. 2012 Apr 1;443(1):165-71. doi: 10.1042/BJ20111748. PubMed
ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells. Wang S, Chen XA, Hu J, Jiang JK, Li Y, Chan-Salis KY, Gu Y, Chen G, Thomas C, Pugh BF, Wang Y. Mol Cancer Ther. 2015 Apr;14(4):877-88. doi: 10.1158/1535-7163.MCT-14-1093-T. Epub 2015 Jan 22. PubMed
Assays for induction of the unfolded protein response and selective activation of the three major pathways. Gupta A, Read DE, Gupta S. Methods Mol Biol. 2015;1292:19-38. doi: 10.1007/978-1-4939-2522-3_2. PubMed
Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia. Sujobert P, Poulain L, Paubelle E, Zylbersztejn F, Grenier A, Lambert M, Townsend EC, Brusq JM, Nicodeme E, Decrooqc J, Nepstad I, Green AS, Mondesir J, Hospital MA, Jacque N, Christodoulou A, Desouza TA, Hermine O, Foretz M, Viollet B, Lacombe C, Mayeux P, Weinstock DM, Moura IC, Bouscary D, Tamburini J. Cell Rep. 2015 Jun 9;11(9):1446-57. doi: 10.1016/j.celrep.2015.04.063. Epub 2015 May 21. PubMed
A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells. Gowen BG, Chim B, Marceau CD, Greene TT, Burr P, Gonzalez JR, Hesser CR, Dietzen PA, Russell T, Iannello A, Coscoy L, Sentman CL, Carette JE, Muljo SA, Raulet DH. Elife. 2015 Nov 13;4. pii: e08474. doi: 10.7554/eLife.08474. PubMed
NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2alpha-ATF4 signalling in breast cancer. Gupta A, Hossain MM, Miller N, Kerin M, Callagy G, Gupta S. Oncogene. 2016 Apr 25. doi: 10.1038/onc.2016.121. PubMed
Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome. Cagalinec M, Liiv M, Hodurova Z, Hickey MA, Vaarmann A, Mandel M, Zeb A, Choubey V, Kuum M, Safiulina D, Vasar E, Veksler V, Kaasik A. PLoS Biol. 2016 Jul 19;14(7):e1002511. doi: 10.1371/journal.pbio.1002511. eCollection 2016 Jul. PubMed
Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells. Masuda M, Miyazaki-Anzai S, Keenan AL, Shiozaki Y, Okamura K, Chick WS, Williams K, Zhao X, Rahman SM, Tintut Y, Adams CM, Miyazaki M. JCI Insight. 2016 Nov 3;1(18):e88646. PubMed
ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Linares JF, Cordes T, Duran A, Reina-Campos M, Valencia T, Ahn CS, Castilla EA, Moscat J, Metallo CM, Diaz-Meco MT. Cell Metab. 2017 Dec 5;26(6):817-829.e6. doi: 10.1016/j.cmet.2017.09.001. Epub 2017 Oct 5. PubMed
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Hitzel J, Lee E, Zhang Y, Bibli SI, Li X, Zukunft S, Pfluger B, Hu J, Schurmann C, Vasconez AE, Oo JA, Kratzer A, Kumar S, Rezende F, Josipovic I, Thomas D, Giral H, Schreiber Y, Geisslinger G, Fork C, Yang X, Sigala F, Romanoski CE, Kroll J, Jo H, Landmesser U, Lusis AJ, Namgaladze D, Fleming I, Leisegang MS, Zhu J, Brandes RP. Nat Commun. 2018 Jun 12;9(1):2292. doi: 10.1038/s41467-018-04602-0. PubMed
Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway. Xia Y, Ye B, Ding J, Yu Y, Alptekin A, Thangaraju M, Prasad PD, Ding ZC, Park EJ, Choi JH, Gao B, Fiehn O, Yan C, Dong Z, Zha Y, Ding HF. Cancer Res. 2019 Aug 1;79(15):3837-3850. doi: 10.1158/0008-5472.CAN-18-3541. Epub 2019 May 14. PubMed
PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes. Jeong MH, Jeong HJ, Ahn BY, Pyun JH, Kwon I, Cho H, Kang JS. Cell Death Dis. 2019 Dec 2;10(12):903. doi: 10.1038/s41419-019-2147-3. PubMed
Insulin-like growth factor 1-receptor signaling stimulates GRP78 expression through the PI3K/AKT/mTOR/ATF4 axis. Ha DP, Lee AS. Cell Signal. 2020 Nov;75:109736. doi: 10.1016/j.cellsig.2020.109736. Epub 2020 Aug 14. PubMed
Wogonin, a Compound in Scutellaria baicalensis, Activates ATF4-FGF21 Signaling in Mouse Hepatocyte AML12 Cells. Yamada Y, Saito H, Araki M, Tsuchimoto Y, Muroi SI, Suzuki K, Toume K, Kim JD, Matsuzaka T, Sone H, Shimano H, Nakagawa Y. Nutrients. 2022 Sep 21;14(19):3920. doi: 10.3390/nu14193920. PubMed
RASSF1 is identified by transcriptome coordination analysis as a target of ATF4. Zhang Y, Huynh-Dam KT, Ding X, Sikirzhytski V, Lim CU, Broude E, Kiaris H. FEBS Open Bio. 2023 Mar;13(3):556-569. doi: 10.1002/2211-5463.13569. Epub 2023 Feb 14. PubMed
CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology. Gouveia Roque C, Chung KM, McCurdy EP, Jagannathan R, Randolph LK, Herline-Killian K, Baleriola J, Hengst U. Sci Adv. 2023 Mar 3;9(9):eadd2671. doi: 10.1126/sciadv.add2671. Epub 2023 Mar 3. PubMed
Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC. Du L, Yang H, Ren Y, Ding Y, Xu Y, Zi X, Liu H, He P. Cell Death Dis. 2023 Nov 3;14(11):716. doi: 10.1038/s41419-023-06238-5. PubMed

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