pLKO-PTEN-shRNA-1320 Citations (9)
Originally described in: Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA.Kim JS, Lee C, Bonifant CL, Ressom H, Waldman T Mol Cell Biol. 2007 Jan . 27(2):662-77. PubMed Journal
Articles Citing pLKO-PTEN-shRNA-1320
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mTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy. Kim EJ, Jeong JH, Bae S, Kang S, Kim CH, Lim YB. J Cell Biochem. 2013 Jun;114(6):1248-56. doi: 10.1002/jcb.24465. PubMed |
Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells. Zhao B, Shah P, Budanov AV, Qiang L, Ming M, Aplin A, Sims DM, He YY. J Biol Chem. 2014 Dec 26;289(52):35806-14. doi: 10.1074/jbc.M114.595397. Epub 2014 Nov 6. PubMed |
MicroRNA-130a promotes the metastasis and epithelial-mesenchymal transition of osteosarcoma by targeting PTEN. Chen J, Yan D, Wu W, Zhu J, Ye W, Shu Q. Oncol Rep. 2016 Jun;35(6):3285-92. doi: 10.3892/or.2016.4719. Epub 2016 Mar 31. PubMed |
MicroRNA-92a promotes metastasis of nasopharyngeal carcinoma by targeting the PTEN/AKT pathway. Zhang H, Cao H, Xu D, Zhu K. Onco Targets Ther. 2016 Jun 16;9:3579-88. doi: 10.2147/OTT.S105470. eCollection 2016. PubMed |
Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes. Zhao B, Shah P, Qiang L, He TC, Budanov A, He YY. Photochem Photobiol. 2016 Jul 27. doi: 10.1111/php.12624. PubMed |
Differential regulation of the pro-inflammatory biomarker, YKL-40/CHI3L1, by PTEN/Phosphoinositide 3-kinase and JAK2/STAT3 pathways in glioblastoma. Wang Y, Wong CW, Yan M, Li L, Liu T, Or PM, Tsui SK, Waye MM, Chan AM. Cancer Lett. 2018 Aug 10;429:54-65. doi: 10.1016/j.canlet.2018.04.040. Epub 2018 May 3. PubMed |
INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors. Li Q, Jiang B, Guo J, Shao H, Del Priore IS, Chang Q, Kudo R, Li Z, Razavi P, Liu B, Boghossian AS, Rees MG, Ronan MM, Roth JA, Donovan KA, Palafox M, Reis-Filho JS, de Stanchina E, Fischer ES, Rosen N, Serra V, Koff A, Chodera JD, Gray NS, Chandarlapaty S. Cancer Discov. 2022 Feb;12(2):356-371. doi: 10.1158/2159-8290.CD-20-1726. Epub 2021 Sep 20. PubMed |
Down-regulation of miR-424 inhibited the metastasis of endometrial carcinoma via targeting PTEN/PI3K/AKT signaling pathway. Lu Y, Lin Q, Lin C, Chen J, Jiang X, He H. J Cancer. 2023 Sep 4;14(15):2811-2819. doi: 10.7150/jca.87021. eCollection 2023. PubMed |
Neratinib, a pan ERBB/HER inhibitor, restores sensitivity of PTEN-null, BRAFV600E melanoma to BRAF/MEK inhibition. DuBose E, Bevill SM, Mitchell DK, Sciaky N, Golitz BT, Dixon SAH, Rhodes SD, Bear JE, Johnson GL, Angus SP. Front Oncol. 2024 May 16;14:1191217. doi: 10.3389/fonc.2024.1191217. eCollection 2024. PubMed |
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