pLKO-p53-shRNA-427 Citations (10)

Originally described in: Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA.
Kim JS, Lee C, Bonifant CL, Ressom H, Waldman T Mol Cell Biol. 2007 Jan . 27(2):662-77. PubMed Journal

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Articles Citing pLKO-p53-shRNA-427

Articles
Small-molecule inhibitors of USP7 induce apoptosis through oxidative and endoplasmic reticulum stress in cancer cells. Lee G, Oh TI, Um KB, Yoon H, Son J, Kim BM, Kim HI, Kim H, Kim YJ, Lee CS, Lim JH. Biochem Biophys Res Commun. 2016 Jan 29;470(1):181-6. doi: 10.1016/j.bbrc.2016.01.021. Epub 2016 Jan 6. PubMed
Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL. Le Pen J, Laurent M, Sarosiek K, Vuillier C, Gautier F, Montessuit S, Martinou JC, Letai A, Braun F, Juin PP. Cell Death Dis. 2016 Feb 4;7:e2083. doi: 10.1038/cddis.2015.400. PubMed
ERbeta decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function. Bado I, Nikolos F, Rajapaksa G, Gustafsson JA, Thomas C. Oncotarget. 2016 Mar 22;7(12):13599-611. doi: 10.18632/oncotarget.7300. PubMed
ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress. Kemp MG, Sancar A. J Biol Chem. 2016 Apr 22;291(17):9330-42. doi: 10.1074/jbc.M116.719740. Epub 2016 Mar 3. PubMed
CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling. Narayanaswamy PB, Tkachuk S, Haller H, Dumler I, Kiyan Y. Cell Death Dis. 2016 Sep 29;7(9):e2383. doi: 10.1038/cddis.2016.291. PubMed
Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression. Xu WW, Li B, Guan XY, Chung SK, Wang Y, Yip YL, Law SY, Chan KT, Lee NP, Chan KW, Xu LY, Li EM, Tsao SW, He QY, Cheung AL. Nat Commun. 2017 Feb 10;8:14399. doi: 10.1038/ncomms14399. PubMed
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Aho ER, Wang J, Gogliotti RD, Howard GC, Phan J, Acharya P, Macdonald JD, Cheng K, Lorey SL, Lu B, Wenzel S, Foshage AM, Alvarado J, Wang F, Shaw JG, Zhao B, Weissmiller AM, Thomas LR, Vakoc CR, Hall MD, Hiebert SW, Liu Q, Stauffer SR, Fesik SW, Tansey WP. Cell Rep. 2019 Mar 12;26(11):2916-2928.e13. doi: 10.1016/j.celrep.2019.02.047. PubMed
Hereditary hemochromatosis disrupts uric acid homeostasis and causes hyperuricemia via altered expression/activity of xanthine oxidase and ABCG2. Ristic B, Sivaprakasam S, Narayanan M, Ganapathy V. Biochem J. 2020 Apr 30;477(8):1499-1513. doi: 10.1042/BCJ20190873. PubMed
Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype. Ma S, McGuire MH, Mangala LS, Lee S, Stur E, Hu W, Bayraktar E, Villar-Prados A, Ivan C, Wu SY, Yokoi A, Dasari SK, Jennings NB, Liu J, Lopez-Berestein G, Ram P, Sood AK. Cell Rep. 2021 Feb 9;34(6):108726. doi: 10.1016/j.celrep.2021.108726. PubMed
Cancer-associated MDM2 W329G mutant attenuates ribosomal stress-mediated p53 responses to promote cell survival and glycolysis. Lien S, Whitbread TP, Shastri SO, Contreras JA, Zhao R, Zhu Y. Am J Cancer Res. 2024 May 15;14(5):2141-2156. doi: 10.62347/QIFC4021. eCollection 2024. PubMed

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