pCMV-myc-Atg5 Citations (11)
Originally described in: A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, Tsokos M, Alt FW, Finkel T Proc Natl Acad Sci U S A. 2008 Mar 4. 105(9):3374-9. PubMed Journal
Articles Citing pCMV-myc-Atg5
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Beclin 1-mediated autophagy in hepatocellular carcinoma cells: implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling. Zou M, Lu N, Hu C, Liu W, Sun Y, Wang X, You Q, Gu C, Xi T, Guo Q. Cell Signal. 2012 Aug;24(8):1722-32. doi: 10.1016/j.cellsig.2012.04.009. Epub 2012 Apr 25. PubMed |
Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, Gao Q, Debatin KM, Beltinger C, Wei J. J Virol. 2014 May;88(9):5152-64. doi: 10.1128/JVI.03851-13. Epub 2014 Feb 26. PubMed |
Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells. Zhao X, Fang Y, Yang Y, Qin Y, Wu P, Wang T, Lai H, Meng L, Wang D, Zheng Z, Lu X, Zhang H, Gao Q, Zhou J, Ma D. Autophagy. 2015 Oct 3;11(10):1849-63. doi: 10.1080/15548627.2015.1017185. PubMed |
Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay
Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, Schulman BA, Xu J, Semple I, Ro SH, Kim B, Mavioglu RN, Tolun A, Jipa A, Takats S, Karpati M, Li JZ, Yapici Z, Juhasz G, Lee JH, Klionsky DJ, Burmeister M.
Elife. 2016 Jan 26;5. pii: e12245. doi: 10.7554/eLife.12245.
PubMed
Associated Plasmids |
An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes. Yan J, Hedl M, Abraham C. J Clin Invest. 2017 Jun 1;127(6):2192-2205. doi: 10.1172/JCI86282. Epub 2017 Apr 24. PubMed |
Aberrant SIRT6 expression contributes to melanoma growth: Role of the autophagy paradox and IGF-AKT signaling. Wang L, Guo W, Ma J, Dai W, Liu L, Guo S, Chen J, Wang H, Yang Y, Yi X, Wang G, Gao T, Zhu G, Li C. Autophagy. 2018;14(3):518-533. doi: 10.1080/15548627.2017.1384886. Epub 2017 Dec 31. PubMed |
IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and IRF5 Immune-Mediated Disease Risk Variants Modulate This Outcome. Hedl M, Yan J, Witt H, Abraham C. J Immunol. 2019 Feb 1;202(3):920-930. doi: 10.4049/jimmunol.1800226. Epub 2018 Dec 28. PubMed |
HIF1alpha promotes prostate cancer progression by increasing ATG5 expression. Yu K, Xiang L, Li S, Wang S, Chen C, Mu H. Anim Cells Syst (Seoul). 2019 Aug 28;23(5):326-334. doi: 10.1080/19768354.2019.1658637. eCollection 2019. PubMed |
Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation. Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C. Gastroenterology. 2020 Jul 18. pii: S0016-5085(20)34953-2. doi: 10.1053/j.gastro.2020.07.024. PubMed |
TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants. Sun R, Hedl M, Abraham C. Cell Mol Gastroenterol Hepatol. 2021;11(1):249-272. doi: 10.1016/j.jcmgh.2020.08.003. Epub 2020 Aug 19. PubMed |
Toxoplasma gondii CDPK3 Controls the Intracellular Proliferation of Parasites in Macrophages. Wu M, An R, Zhou N, Chen Y, Cai H, Yan Q, Wang R, Luo Q, Yu L, Chen L, Du J. Front Immunol. 2022 Jun 10;13:905142. doi: 10.3389/fimmu.2022.905142. eCollection 2022. PubMed |
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