pEGFP-LC3 (human) Citations (91)
Originally described in: A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, Tsokos M, Alt FW, Finkel T Proc Natl Acad Sci U S A. 2008 Mar 4. 105(9):3374-9. PubMed Journal
Articles Citing pEGFP-LC3 (human)
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| Prolylcarboxypeptidase regulates proliferation, autophagy, and resistance to 4-hydroxytamoxifen-induced cytotoxicity in estrogen receptor-positive breast cancer cells. Duan L, Motchoulski N, Danzer B, Davidovich I, Shariat-Madar Z, Levenson VV. J Biol Chem. 2011 Jan 28;286(4):2864-76. doi: 10.1074/jbc.M110.143271. Epub 2010 Nov 17. PubMed |
| Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2. Liu H, Yu S, Zhang H, Xu J. PLoS One. 2012;7(10):e46720. doi: 10.1371/journal.pone.0046720. Epub 2012 Oct 3. PubMed |
| Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cells. Zhang Q, Si S, Schoen S, Chen J, Jin XB, Wu G. J Exp Clin Cancer Res. 2013 Dec 4;32:99. doi: 10.1186/1756-9966-32-99. PubMed |
| Folliculin deficient renal cancer cells show higher radiosensitivity through autophagic cell death. Zhang Q, Si S, Schoen S, Jin XB, Chen J, Wu G. J Urol. 2014 Jun;191(6):1880-8. doi: 10.1016/j.juro.2014.01.001. Epub 2014 Jan 13. PubMed |
| Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer. Wang M, Shim JS, Li RJ, Dang Y, He Q, Das M, Liu JO. Br J Pharmacol. 2014 Oct;171(19):4478-89. doi: 10.1111/bph.12800. Epub 2014 Sep 5. PubMed |
| Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors. Yeh ES, Abt MA, Hill EG. Breast Cancer Res Treat. 2015 Jan;149(1):91-8. doi: 10.1007/s10549-014-3227-9. Epub 2014 Dec 17. PubMed |
| A role for the autophagy regulator Transcription Factor EB in amiodarone-induced phospholipidosis. Buratta S, Urbanelli L, Ferrara G, Sagini K, Goracci L, Emiliani C. Biochem Pharmacol. 2015 Jun 1;95(3):201-9. doi: 10.1016/j.bcp.2015.03.017. Epub 2015 Apr 13. PubMed |
| The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells. Rui YN, Xu Z, Chen Z, Zhang S. Autophagy. 2015;11(5):812-32. doi: 10.1080/15548627.2015.1034402. PubMed |
| N-Myc and STAT Interactor regulates autophagy and chemosensitivity in breast cancer cells. Metge BJ, Mitra A, Chen D, Shevde LA, Samant RS. Sci Rep. 2015 Jul 6;5:11995. doi: 10.1038/srep11995. PubMed |
| A Novel Role of Proline Oxidase in HIV-1 Envelope Glycoprotein-induced Neuronal Autophagy. Pandhare J, Dash S, Jones B, Villalta F, Dash C. J Biol Chem. 2015 Oct 16;290(42):25439-51. doi: 10.1074/jbc.M115.652776. Epub 2015 Sep 1. PubMed |
| Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1alpha-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells. Tang ZH, Zhang LL, Li T, Lu JH, Ma DL, Leung CH, Chen XP, Jiang HL, Wang YT, Lu JJ. Oncotarget. 2015 Dec 22;6(41):43911-26. doi: 10.18632/oncotarget.6084. PubMed |
| Induction of autophagy and apoptosis by miR-148a through the sonic hedgehog signaling pathway in hepatic stellate cells. Liu XY, He YJ, Yang QH, Huang W, Liu ZH, Ye GR, Tang SH, Shu JC. Am J Cancer Res. 2015 Aug 15;5(9):2569-89. eCollection 2015. PubMed |
| EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex. Lei Y, Kansy BA, Li J, Cong L, Liu Y, Trivedi S, Wen H, Ting JP, Ouyang H, Ferris RL. Oncogene. 2016 Feb 15. doi: 10.1038/onc.2016.11. PubMed |
| Dose-dependent autophagic effect of titanium dioxide nanoparticles in human HaCaT cells at non-cytotoxic levels. Lopes VR, Loitto V, Audinot JN, Bayat N, Gutleb AC, Cristobal S. J Nanobiotechnology. 2016 Mar 22;14:22. doi: 10.1186/s12951-016-0174-0. PubMed |
| Inhibition of autophagy potentiates anticancer property of 20(S)-ginsenoside Rh2 by promoting mitochondria-dependent apoptosis in human acute lymphoblastic leukaemia cells. Xia T, Wang J, Wang Y, Wang Y, Cai J, Wang M, Chen Q, Song J, Yu Z, Huang W, Fang J. Oncotarget. 2016 May 10;7(19):27336-49. doi: 10.18632/oncotarget.8285. PubMed |
| Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Tang ZH, Chen X, Wang ZY, Chai K, Wang YF, Xu XH, Wang XW, Lu JH, Wang YT, Chen XP, Lu JJ. Sci Rep. 2016 May 17;6:26241. doi: 10.1038/srep26241. PubMed |
| Transient Oxygen/Glucose Deprivation Causes a Delayed Loss of Mitochondria and Increases Spontaneous Calcium Signaling in Astrocytic Processes. O'Donnell JC, Jackson JG, Robinson MB. J Neurosci. 2016 Jul 6;36(27):7109-27. doi: 10.1523/JNEUROSCI.4518-15.2016. PubMed |
| AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production. Mahil SK, Twelves S, Farkas K, Setta-Kaffetzi N, Burden AD, Gach JE, Irvine AD, Kepiro L, Mockenhaupt M, Oon HH, Pinner J, Ranki A, Seyger MM, Soler-Palacin P, Storan ER, Tan ES, Valeyrie-Allanore L, Young HS, Trembath RC, Choon SE, Szell M, Bata-Csorgo Z, Smith CH, Di Meglio P, Barker JN, Capon F. J Invest Dermatol. 2016 Nov;136(11):2251-2259. doi: 10.1016/j.jid.2016.06.618. Epub 2016 Jul 5. PubMed |
| Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Ryu D, Mouchiroud L, Andreux PA, Katsyuba E, Moullan N, Nicolet-Dit-Felix AA, Williams EG, Jha P, Lo Sasso G, Huzard D, Aebischer P, Sandi C, Rinsch C, Auwerx J. Nat Med. 2016 Aug;22(8):879-88. doi: 10.1038/nm.4132. Epub 2016 Jul 11. PubMed |
| Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome. Cagalinec M, Liiv M, Hodurova Z, Hickey MA, Vaarmann A, Mandel M, Zeb A, Choubey V, Kuum M, Safiulina D, Vasar E, Veksler V, Kaasik A. PLoS Biol. 2016 Jul 19;14(7):e1002511. doi: 10.1371/journal.pbio.1002511. eCollection 2016 Jul. PubMed |
| Transient Proteotoxicity of Bacterial Virulence Factor Pyocyanin in Renal Tubular Epithelial Cells Induces ER-Related Vacuolation and Can Be Efficiently Modulated by Iron Chelators. Mossine VV, Waters JK, Chance DL, Mawhinney TP. Toxicol Sci. 2016 Dec;154(2):403-415. Epub 2016 Sep 9. PubMed |
| A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Wei RJ, Lin SS, Wu WR, Chen LR, Li CF, Chen HD, Chou CT, Chen YC, Liang SS, Chien ST, Shiue YL. Toxicol Appl Pharmacol. 2016 Nov 15;311:88-98. doi: 10.1016/j.taap.2016.09.021. Epub 2016 Sep 24. PubMed |
| Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis. Coly PM, Perzo N, Le Joncour V, Lecointre C, Schouft MT, Desrues L, Tonon MC, Wurtz O, Gandolfo P, Castel H, Morin F. Autophagy. 2016 Dec;12(12):2344-2362. Epub 2016 Oct 7. PubMed |
| Tazarotene-Induced Gene 1 Enhanced Cervical Cell Autophagy through Transmembrane Protein 192. Shyu RY, Wang CH, Wu CC, Chen ML, Lee MC, Wang LK, Jiang SY, Tsai FM. Mol Cells. 2016 Dec;39(12):877-887. doi: 10.14348/molcells.2016.0161. Epub 2016 Dec 13. PubMed |
| Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Liu YH, Weng YP, Lin HY, Tang SW, Chen CJ, Liang CJ, Ku CY, Lin JY. Sci Rep. 2017 Jan 30;7:41437. doi: 10.1038/srep41437. PubMed |
| Heat Shock-induced Phosphorylation of TAR DNA-binding Protein 43 (TDP-43) by MAPK/ERK Kinase Regulates TDP-43 Function. Li W, Reeb AN, Lin B, Subramanian P, Fey EE, Knoverek CR, French RL, Bigio EH, Ayala YM. J Biol Chem. 2017 Mar 24;292(12):5089-5100. doi: 10.1074/jbc.M116.753913. Epub 2017 Feb 6. PubMed |
| Quercetin induces protective autophagy and apoptosis through ER stress via the p-STAT3/Bcl-2 axis in ovarian cancer. Liu Y, Gong W, Yang ZY, Zhou XS, Gong C, Zhang TR, Wei X, Ma D, Ye F, Gao QL. Apoptosis. 2017 Apr;22(4):544-557. doi: 10.1007/s10495-016-1334-2. PubMed |
| Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells. Tang ZH, Cao WX, Su MX, Chen X, Lu JJ. Toxicol Appl Pharmacol. 2017 Apr 15;321:18-26. doi: 10.1016/j.taap.2017.02.017. Epub 2017 Feb 22. PubMed |
| Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells. Son YO, Pratheeshkumar P, Divya SP, Zhang Z, Shi X. J Biol Chem. 2017 May 19;292(20):8315-8330. doi: 10.1074/jbc.M116.773986. Epub 2017 Mar 22. PubMed |
| Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme. Wang L, Gundelach JH, Bram RJ. Cell Death Dis. 2017 May 18;8(5):e2807. doi: 10.1038/cddis.2017.217. PubMed |
| HCV-induced oxidative stress by inhibition of Nrf2 triggers autophagy and favors release of viral particles. Medvedev R, Ploen D, Spengler C, Elgner F, Ren H, Bunten S, Hildt E. Free Radic Biol Med. 2017 Sep;110:300-315. doi: 10.1016/j.freeradbiomed.2017.06.021. Epub 2017 Jun 30. PubMed |
| ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Linares JF, Cordes T, Duran A, Reina-Campos M, Valencia T, Ahn CS, Castilla EA, Moscat J, Metallo CM, Diaz-Meco MT. Cell Metab. 2017 Dec 5;26(6):817-829.e6. doi: 10.1016/j.cmet.2017.09.001. Epub 2017 Oct 5. PubMed |
| Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer. Tang ZH, Cao WX, Guo X, Dai XY, Lu JH, Chen X, Zhu H, Lu JJ. Cancer Lett. 2018 Jan 1;412:1-9. doi: 10.1016/j.canlet.2017.10.001. Epub 2017 Oct 9. PubMed |
| Simultaneous Detection of Autophagy and Epithelial to Mesenchymal Transition in the Non-small Cell Lung Cancer Cells. Alizadeh J, Shojaei S, Sepanjnia A, Hashemi M, Eftekharpour E, Ghavami S. Methods Mol Biol. 2017 Nov 4. doi: 10.1007/7651_2017_84. PubMed |
| Ferroquine, the next generation antimalarial drug, has antitumor activity. Kondratskyi A, Kondratska K, Vanden Abeele F, Gordienko D, Dubois C, Toillon RA, Slomianny C, Lemiere S, Delcourt P, Dewailly E, Skryma R, Biot C, Prevarskaya N. Sci Rep. 2017 Nov 21;7(1):15896. doi: 10.1038/s41598-017-16154-2. PubMed |
| CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation. Mishra SK, Gao YG, Deng Y, Chalfant CE, Hinchcliffe EH, Brown RE. Autophagy. 2018 Feb 21:1-18. doi: 10.1080/15548627.2017.1393129. PubMed |
| Combined pitavastatin and dacarbazine treatment activates apoptosis and autophagy resulting in synergistic cytotoxicity in melanoma cells. Al-Qatati A, Aliwaini S. Oncol Lett. 2017 Dec;14(6):7993-7999. doi: 10.3892/ol.2017.7189. Epub 2017 Oct 16. PubMed |
| Polysaccharide from Fuzi protects against OxLDLinduced calcification of human vascular smooth muscle cells by increasing autophagic activity. Liao L, Zhuang X, Li W, Su Q, Zhao J, Liu Y. Mol Med Rep. 2018 Apr;17(4):5109-5115. doi: 10.3892/mmr.2018.8488. Epub 2018 Jan 25. PubMed |
| Inhibition of autophagy-attenuated calcium oxalate crystal-induced renal tubular epithelial cell injury in vivo and in vitro. Liu Y, Li D, He Z, Liu Q, Wu J, Guan X, Tao Z, Deng Y. Oncotarget. 2017 Dec 17;9(4):4571-4582. doi: 10.18632/oncotarget.23383. eCollection 2018 Jan 12. PubMed |
| IL-12+IL-18 Cosignaling in Human Macrophages and Lung Epithelial Cells Activates Cathelicidin and Autophagy, Inhibiting Intracellular Mycobacterial Growth. Yang R, Yang E, Shen L, Modlin RL, Shen H, Chen ZW. J Immunol. 2018 Apr 1;200(7):2405-2417. doi: 10.4049/jimmunol.1701073. Epub 2018 Feb 16. PubMed |
| Rab9-dependent autophagy is required for the IGF-IIR triggering mitophagy to eliminate damaged mitochondria. Huang CY, Kuo WW, Ho TJ, Chiang SF, Pai PY, Lin JY, Lin DY, Kuo CH, Huang CY. J Cell Physiol. 2018 Sep;233(9):7080-7091. doi: 10.1002/jcp.26346. Epub 2018 Mar 25. PubMed |
| Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine. Tan YS, Sansanaphongpricha K, Xie Y, Donnelly CR, Luo X, Heath BR, Zhao X, Bellile E, Hu H, Chen H, Polverini PJ, Chen Q, Young S, Carey TE, Nor JE, Ferris RL, Wolf GT, Sun D, Lei YL. Clin Cancer Res. 2018 Sep 1;24(17):4242-4255. doi: 10.1158/1078-0432.CCR-17-2807. Epub 2018 May 16. PubMed |
| Roles of ROS, Nrf2, and autophagy in cadmium-carcinogenesis and its prevention by sulforaphane. Wang Y, Mandal AK, Son YO, Pratheeshkumar P, Wise JTF, Wang L, Zhang Z, Shi X, Chen Z. Toxicol Appl Pharmacol. 2018 Aug 15;353:23-30. doi: 10.1016/j.taap.2018.06.003. Epub 2018 Jun 6. PubMed |
| Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts. Torralba D, Baixauli F, Villarroya-Beltri C, Fernandez-Delgado I, Latorre-Pellicer A, Acin-Perez R, Martin-Cofreces NB, Jaso-Tamame AL, Iborra S, Jorge I, Gonzalez-Aseguinolaza G, Garaude J, Vicente-Manzanares M, Enriquez JA, Mittelbrunn M, Sanchez-Madrid F. Nat Commun. 2018 Jul 9;9(1):2658. doi: 10.1038/s41467-018-05077-9. PubMed |
| Macroautophagy Regulates Nuclear NOTCH1 Activity Through Multiple p62 Binding Sites. Zhang T, Guo L, Wang Y, Yang Y. IUBMB Life. 2018 Oct;70(10):985-994. doi: 10.1002/iub.1891. Epub 2018 Sep 12. PubMed |
| Sulforaphane induces autophagy by inhibition of HDAC6-mediated PTEN activation in triple negative breast cancer cells. Yang F, Wang F, Liu Y, Wang S, Li X, Huang Y, Xia Y, Cao C. Life Sci. 2018 Nov 15;213:149-157. doi: 10.1016/j.lfs.2018.10.034. Epub 2018 Oct 20. PubMed |
| Autophagy modulates temozolomide-induced cell death in alveolar Rhabdomyosarcoma cells. Moghadam AR, da Silva Rosa SC, Samiei E, Alizadeh J, Field J, Kawalec P, Thliveris J, Akbari M, Ghavami S, Gordon JW. Cell Death Discov. 2018 Oct 25;4:52. doi: 10.1038/s41420-018-0115-9. eCollection 2018. PubMed |
| Cigarette smoke induces ROS mediated autophagy impairment in human corneal epithelial cells. Miao Q, Xu Y, Zhang H, Xu P, Ye J. Environ Pollut. 2019 Feb;245:389-397. doi: 10.1016/j.envpol.2018.11.028. Epub 2018 Nov 9. PubMed |
| Miro proteins prime mitochondria for Parkin translocation and mitophagy. Safiulina D, Kuum M, Choubey V, Gogichaishvili N, Liiv J, Hickey MA, Cagalinec M, Mandel M, Zeb A, Liiv M, Kaasik A. EMBO J. 2019 Jan 15;38(2). pii: embj.201899384. doi: 10.15252/embj.201899384. Epub 2018 Nov 30. PubMed |
| A VPS33A-binding motif on syntaxin 17 controls autophagy completion in mammalian cells. Saleeb RS, Kavanagh DM, Dun AR, Dalgarno PA, Duncan RR. J Biol Chem. 2019 Mar 15;294(11):4188-4201. doi: 10.1074/jbc.RA118.005947. Epub 2019 Jan 17. PubMed |
| Recombinant adenoviruses expressing apoptin suppress the growth of MCF7 breast cancer cells and affect cell autophagy. Chen S, Li YQ, Yin XZ, Li SZ, Zhu YL, Fan YY, Li WJ, Cui YL, Zhao J, Li X, Zhang QG, Jin NY. Oncol Rep. 2019 May;41(5):2818-2832. doi: 10.3892/or.2019.7077. Epub 2019 Mar 18. PubMed |
| Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis. Fernandez-Mosquera L, Yambire KF, Couto R, Pereyra L, Pabis K, Ponsford AH, Diogo CV, Stagi M, Milosevic I, Raimundo N. Autophagy. 2019 Sep;15(9):1572-1591. doi: 10.1080/15548627.2019.1586256. Epub 2019 Mar 27. PubMed |
| The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity. Gan L, Seki A, Shen K, Iyer H, Han K, Hayer A, Wollman R, Ge X, Lin JR, Dey G, Talbot WS, Meyer T. Nat Cell Biol. 2019 May;21(5):614-626. doi: 10.1038/s41556-019-0321-6. Epub 2019 Apr 29. PubMed |
| PRRSV activates lipophagy to facilitate viral replication through down-regulation of NDRG1 expression. Wang J, Liu JY, Shao KY, Han YQ, Li GL, Ming SL, Su BQ, Du YK, Liu ZH, Zhang GP, Yang GY, Chu BB. J Virol. 2019 Jun 12. pii: JVI.00526-19. doi: 10.1128/JVI.00526-19. PubMed |
| Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition. Emami A, Shojaei S, da Silva Rosa SC, Aghaei M, Samiei E, Vosoughi AR, Kalantari F, Kawalec P, Thliveris J, Sharma P, Zeki AA, Akbari M, Gordon JW, Ghavami S. Eur J Pharmacol. 2019 Nov 5;862:172616. doi: 10.1016/j.ejphar.2019.172616. Epub 2019 Aug 23. PubMed |
| The metabolic regulator Lamtor5 suppresses inflammatory signaling via regulating mTOR-mediated TLR4 degradation. Zhang W, Zhuang N, Liu X, He L, He Y, Mahinthichaichan P, Zhang H, Kang Y, Lu Y, Wu Q, Xu D, Shi L. Cell Mol Immunol. 2019 Aug 29. pii: 10.1038/s41423-019-0281-6. doi: 10.1038/s41423-019-0281-6. PubMed |
| A second open reading frame in human enterovirus determines viral replication in intestinal epithelial cells. Guo H, Li Y, Liu G, Jiang Y, Shen S, Bi R, Huang H, Cheng T, Wang C, Wei W. Nat Commun. 2019 Sep 6;10(1):4066. doi: 10.1038/s41467-019-12040-9. PubMed |
| Sirtuin Family Members Selectively Regulate Autophagy in Osteosarcoma and Mesothelioma Cells in Response to Cellular Stress. Garva R, Thepmalee C, Yasamut U, Sudsaward S, Guazzelli A, Rajendran R, Tongmuang N, Khunchai S, Meysami P, Limjindaporn T, Yenchitsomanus PT, Mutti L, Krstic-Demonacos M, Demonacos C. Front Oncol. 2019 Sep 24;9:949. doi: 10.3389/fonc.2019.00949. eCollection 2019. PubMed |
| HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING. Luo X, Donnelly CR, Gong W, Heath BR, Hao Y, Donnelly LA, Moghbeli T, Tan YS, Lin X, Bellile E, Kansy BA, Carey TE, Brenner JC, Cheng L, Polverini PJ, Morgan MA, Wen H, Prince ME, Ferris RL, Xie Y, Young S, Wolf GT, Chen Q, Lei YL. J Clin Invest. 2020 Apr 1;130(4):1635-1652. doi: 10.1172/JCI129497. PubMed |
| Methods for Studying TNFalpha-Induced Autophagy. Najafi S, Abo-Ali EM, Dukhande VV. Methods Mol Biol. 2020;2108:131-146. doi: 10.1007/978-1-0716-0247-8_12. PubMed |
| KRT8 phosphorylation regulates the epithelial-mesenchymal transition in retinal pigment epithelial cells through autophagy modulation. Miao Q, Xu Y, Yin H, Zhang H, Ye J. J Cell Mol Med. 2020 Mar;24(5):3217-3228. doi: 10.1111/jcmm.14998. Epub 2020 Feb 5. PubMed |
| Proteaphagy in Mammalian Cells Can Function Independent of ATG5/ATG7. Goebel T, Mausbach S, Tuermer A, Eltahir H, Winter D, Gieselmann V, Thelen M. Mol Cell Proteomics. 2020 Jul;19(7):1120-1131. doi: 10.1074/mcp.RA120.001983. Epub 2020 Apr 16. PubMed |
| MicroRNA-100 Enhances Autophagy and Suppresses Migration and Invasion of Renal Cell Carcinoma Cells via Disruption of NOX4-Dependent mTOR Pathway. Liu X, Zhong L, Li P, Zhao P. Clin Transl Sci. 2020 May 1. doi: 10.1111/cts.12798. PubMed |
| Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells. Yu H, Zhou X, Wang Y, Huang X, Yang J, Zeng J, Li G, Xie X, Zhang J. Cancer Cell Int. 2020 May 24;20:191. doi: 10.1186/s12935-020-01279-8. eCollection 2020. PubMed |
| Puerarin 6''-O-xyloside suppressed HCC via regulating proliferation, stemness, and apoptosis with inhibited PI3K/AKT/mTOR. Li L, Liu JD, Gao GD, Zhang K, Song YW, Li HB. Cancer Med. 2020 Sep;9(17):6399-6410. doi: 10.1002/cam4.3285. Epub 2020 Jul 21. PubMed |
| The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease. Wu J, Yu X, Xue K, Wu J, Wang R, Xie X, Li K, Yang Z, Yue J. Oxid Med Cell Longev. 2020 Jul 15;2020:8735249. doi: 10.1155/2020/8735249. eCollection 2020. PubMed |
| Autophagy Upregulation by the TFEB Inducer Trehalose Protects against Oxidative Damage and Cell Death Associated with NRF2 Inhibition in Human RPE Cells. Abokyi S, Shan SW, To CH, Chan HH, Tse DY. Oxid Med Cell Longev. 2020 Jul 21;2020:5296341. doi: 10.1155/2020/5296341. eCollection 2020. PubMed |
| 20(S)-Ginsenoside Rh2 displays efficacy against T-cell acute lymphoblastic leukemia through the PI3K/Akt/mTOR signal pathway. Xia T, Zhang J, Zhou C, Li Y, Duan W, Zhang B, Wang M, Fang J. J Ginseng Res. 2020 Sep;44(5):725-737. doi: 10.1016/j.jgr.2019.07.003. Epub 2019 Jul 30. PubMed |
Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites.
Wu H, Voeltz GK.
Dev Cell. 2021 Jan 11;56(1):52-66.e7. doi: 10.1016/j.devcel.2020.12.014.
PubMed
Associated Plasmids |
| EBV-LMP1 promotes radioresistance by inducing protective autophagy through BNIP3 in nasopharyngeal carcinoma. Xu S, Zhou Z, Peng X, Tao X, Zhou P, Zhang K, Peng J, Li D, Shen L, Yang L. Cell Death Dis. 2021 Apr 1;12(4):344. doi: 10.1038/s41419-021-03639-2. PubMed |
| HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons. Santerre M, Arjona SP, Allen CN, Callen S, Buch S, Sawaya BE. Autophagy. 2021 Jul;17(7):1768-1782. doi: 10.1080/15548627.2021.1915641. Epub 2021 Apr 23. PubMed |
| Parkinson's disease-associated VPS35 mutant reduces mitochondrial membrane potential and impairs PINK1/Parkin-mediated mitophagy. Ma KY, Fokkens MR, Reggiori F, Mari M, Verbeek DS. Transl Neurodegener. 2021 Jun 15;10(1):19. doi: 10.1186/s40035-021-00243-4. PubMed |
| Knockdown of Atg7 suppresses Tumorigenesis in a murine model of liver cancer. Cho KJ, Shin SY, Moon H, Kim BK, Ro SW. Transl Oncol. 2021 Sep;14(9):101158. doi: 10.1016/j.tranon.2021.101158. Epub 2021 Jun 23. PubMed |
| Targeting Lysosomes to Reverse Hydroquinone-Induced Autophagy Defects and Oxidative Damage in Human Retinal Pigment Epithelial Cells. Abokyi S, Shan SW, Lam CH, Catral KP, Pan F, Chan HH, To CH, Tse DY. Int J Mol Sci. 2021 Aug 22;22(16). pii: ijms22169042. doi: 10.3390/ijms22169042. PubMed |
| The core autophagy protein ATG9A controls dynamics of cell protrusions and directed migration. Campisi D, Desrues L, Dembele KP, Mutel A, Parment R, Gandolfo P, Castel H, Morin F. J Cell Biol. 2022 Mar 7;221(3). pii: 213022. doi: 10.1083/jcb.202106014. Epub 2022 Feb 18. PubMed |
| ATG7-mediated autophagy facilitates embryonic stem cell exit from naive pluripotency and marks commitment to differentiation. Zhou J, He H, Zhang JJ, Liu X, Yao W, Li C, Xu T, Yin SY, Wu DY, Dou CL, Li Q, Xiang J, Xiong WJ, Wang LY, Tang JM, Xue Z, Zhang X, Miao YL. Autophagy. 2022 Apr 10:1-23. doi: 10.1080/15548627.2022.2055285. PubMed |
| EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism. Yu PW, Fu PF, Zeng L, Qi YL, Li XQ, Wang Q, Yang GY, Li HW, Wang J, Chu BB, Wang MD. Microbiol Spectr. 2022 Apr 27;10(2):e0227621. doi: 10.1128/spectrum.02276-21. Epub 2022 Apr 11. PubMed |
| Apolipoprotein E potently inhibits ferroptosis by blocking ferritinophagy. Belaidi AA, Masaldan S, Southon A, Kalinowski P, Acevedo K, Appukuttan AT, Portbury S, Lei P, Agarwal P, Leurgans SE, Schneider J, Conrad M, Bush AI, Ayton S. Mol Psychiatry. 2022 Apr 28. pii: 10.1038/s41380-022-01568-w. doi: 10.1038/s41380-022-01568-w. PubMed |
| PAT2 regulates vATPase assembly and lysosomal acidification in brown adipocytes. Wang J, Onogi Y, Krueger M, Oeckl J, Karlina R, Singh I, Hauck SM, Feederle R, Li Y, Ussar S. Mol Metab. 2022 Jul;61:101508. doi: 10.1016/j.molmet.2022.101508. Epub 2022 May 2. PubMed |
| Differential impact of doxorubicin dose on cell death and autophagy pathways during acute cardiotoxicity. Kawalec P, Martens MD, Field JT, Mughal W, Caymo AM, Chapman D, Xiang B, Ghavami S, Dolinsky VW, Gordon JW. Toxicol Appl Pharmacol. 2022 Oct 15;453:116210. doi: 10.1016/j.taap.2022.116210. Epub 2022 Aug 24. PubMed |
| NudC regulated Lis1 stability is essential for the maintenance of dynamic microtubule ends in axon terminals. Kawano D, Pinter K, Chlebowski M, Petralia RS, Wang YX, Nechiporuk AV, Drerup CM. iScience. 2022 Sep 5;25(10):105072. doi: 10.1016/j.isci.2022.105072. eCollection 2022 Oct 21. PubMed |
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