human p53-(94-312) Citations (8)

Originally described in: Latent and active p53 are identical in conformation.
Ayed A, Mulder FA, Yi GS, Lu Y, Kay LE, Arrowsmith CH Nat Struct Biol. 2001 Sep . 8(9):756-60. PubMed Journal

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Articles Citing human p53-(94-312)

Articles
Investigating the intrinsic aggregation potential of evolutionarily conserved segments in p53. Ghosh S, Ghosh D, Ranganathan S, Anoop A, P SK, Jha NN, Padinhateeri R, Maji SK. Biochemistry. 2014 Sep 30;53(38):5995-6010. doi: 10.1021/bi500825d. Epub 2014 Sep 17. PubMed
Aggregation tendencies in the p53 family are modulated by backbone hydrogen bonds. Cino EA, Soares IN, Pedrote MM, de Oliveira GA, Silva JL. Sci Rep. 2016 Sep 7;6:32535. doi: 10.1038/srep32535. PubMed
p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation. Artigas N, Gamez B, Cubillos-Rojas M, Sanchez-de Diego C, Valer JA, Pons G, Rosa JL, Ventura F. Cell Death Differ. 2017 Dec;24(12):2022-2031. doi: 10.1038/cdd.2017.113. Epub 2017 Aug 4. PubMed
Loss of the p53 transactivation domain results in high amyloid aggregation of the Delta40p53 isoform in endometrial carcinoma cells. Melo Dos Santos N, de Oliveira GAP, Ramos Rocha M, Pedrote MM, Diniz da Silva Ferretti G, Pereira Rangel L, Morgado-Diaz JA, Silva JL, Rodrigues Pereira Gimba E. J Biol Chem. 2019 Jun 14;294(24):9430-9439. doi: 10.1074/jbc.RA119.007566. Epub 2019 Apr 26. PubMed
Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands. Petronilho EC, Pedrote MM, Marques MA, Passos YM, Mota MF, Jakobus B, de Sousa GDS, Pereira da Costa F, Felix AL, Ferretti GDS, Almeida FP, Cordeiro Y, Vieira TCRG, de Oliveira GAP, Silva JL. Chem Sci. 2021 Apr 26;12(21):7334-7349. doi: 10.1039/d1sc01739j. PubMed
Oncogenic gain of function due to p53 amyloids occurs through aberrant alteration of cell cycle and proliferation. Navalkar A, Paul A, Sakunthala A, Pandey S, Dey AK, Saha S, Sahoo S, Jolly MK, Maiti TK, Maji SK. J Cell Sci. 2022 Aug 1;135(15). pii: 276165. doi: 10.1242/jcs.259500. Epub 2022 Aug 1. PubMed
Water Leakage Pathway Leads to Internal Hydration of the p53 Core Domain. Lima IDM, Pedrote MM, Marques MA, Sousa GDS, Silva JL, de Oliveira GAP, Cino EA. Biochemistry. 2023 Jan 3;62(1):35-43. doi: 10.1021/acs.biochem.2c00320. Epub 2022 Dec 19. PubMed
Intracellular FGF1 protects cells from apoptosis through direct interaction with p53. Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, Wiedlocha A, Otlewski J, Zakrzewska M. Cell Mol Life Sci. 2023 Oct 2;80(10):311. doi: 10.1007/s00018-023-04964-9. PubMed

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