3XFlag pCMV5-TOPO TAZ (S89A) Citations (12)
Originally described in: TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL Nat Cell Biol. 2008 Jul . 10(7):837-48. PubMed Journal
Articles Citing 3XFlag pCMV5-TOPO TAZ (S89A)
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Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor. Paramasivam M, Sarkeshik A, Yates JR 3rd, Fernandes MJ, McCollum D. Mol Biol Cell. 2011 Oct;22(19):3725-33. doi: 10.1091/mbc.E11-04-0300. Epub 2011 Aug 10. PubMed |
The Hippo effector TAZ (WWTR1) transforms myoblasts and its abundance is associated with reduced survival in embryonal rhabdomyosarcoma. Mohamed A, Sun C, De Mello V, Selfe J, Missiaglia E, Shipley J, Murray GI, Zammit PS, Wackerhage H. J Pathol. 2016 May 17. doi: 10.1002/path.4745. PubMed |
Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow.
Wang L, Luo JY, Li B, Tian XY, Chen LJ, Huang Y, Liu J, Deng D, Lau CW, Wan S, Ai D, Mak KK, Tong KK, Kwan KM, Wang N, Chiu JJ, Zhu Y, Huang Y.
Nature. 2016 Dec 7. doi: 10.1038/nature20602.
PubMed
Associated Plasmids |
YAP regulates cell mechanics by controlling focal adhesion assembly. Nardone G, Oliver-De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, Pesl M, Caluori G, Pagliari S, Martino F, Maceckova Z, Hajduch M, Sanz-Garcia A, Pugno NM, Stokin GB, Forte G. Nat Commun. 2017 May 15;8:15321. doi: 10.1038/ncomms15321. PubMed |
Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function. Sun C, De Mello V, Mohamed A, Ortuste Quiroga HP, Garcia-Munoz A, Al Bloshi A, Tremblay AM, von Kriegsheim A, Collie-Duguid E, Vargesson N, Matallanas D, Wackerhage H, Zammit PS. Stem Cells. 2017 Aug;35(8):1958-1972. doi: 10.1002/stem.2652. Epub 2017 Jun 27. PubMed |
YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development. Neto F, Klaus-Bergmann A, Ong YT, Alt S, Vion AC, Szymborska A, Carvalho JR, Hollfinger I, Bartels-Klein E, Franco CA, Potente M, Gerhardt H. Elife. 2018 Feb 5;7. pii: 31037. doi: 10.7554/eLife.31037. PubMed |
KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer. Knight JF, Sung VYC, Kuzmin E, Couzens AL, de Verteuil DA, Ratcliffe CDH, Coelho PP, Johnson RM, Samavarchi-Tehrani P, Gruosso T, Smith HW, Lee W, Saleh SM, Zuo D, Zhao H, Guiot MC, Davis RR, Gregg JP, Moraes C, Gingras AC, Park M. Cell Rep. 2018 Mar 20;22(12):3191-3205. doi: 10.1016/j.celrep.2018.02.095. PubMed |
Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis. Gui Y, Li J, Lu Q, Feng Y, Wang M, He W, Yang J, Dai C. J Biol Chem. 2018 Oct 19;293(42):16364-16375. doi: 10.1074/jbc.RA118.004073. Epub 2018 Aug 28. PubMed |
TNF-alpha-Induced YAP/TAZ Activity Mediates Leukocyte-Endothelial Adhesion by Regulating VCAM1 Expression in Endothelial Cells. Choi HJ, Kim NE, Kim BM, Seo M, Heo JH. Int J Mol Sci. 2018 Nov 1;19(11). pii: ijms19113428. doi: 10.3390/ijms19113428. PubMed |
The Hippo Effector Transcriptional Coactivator with PDZ-Binding Motif Cooperates with Oncogenic beta-Catenin to Induce Hepatoblastoma Development in Mice and Humans. Zhang S, Zhang J, Evert K, Li X, Liu P, Kiss A, Schaff Z, Ament C, Zhang Y, Serra M, Evert M, Chen N, Xu F, Chen X, Tao J, Calvisi DF, Cigliano A. Am J Pathol. 2020 Jul;190(7):1397-1413. doi: 10.1016/j.ajpath.2020.03.011. Epub 2020 Apr 10. PubMed |
Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells. Van Sciver N, Ohashi M, Pauly NP, Bristol JA, Nelson SE, Johannsen EC, Kenney SC. PLoS Pathog. 2021 Aug 2;17(8):e1009783. doi: 10.1371/journal.ppat.1009783. eCollection 2021 Aug. PubMed |
A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth. Ong YT, Andrade J, Armbruster M, Shi C, Castro M, Costa ASH, Sugino T, Eelen G, Zimmermann B, Wilhelm K, Lim J, Watanabe S, Guenther S, Schneider A, Zanconato F, Kaulich M, Pan D, Braun T, Gerhardt H, Efeyan A, Carmeliet P, Piccolo S, Grosso AR, Potente M. Nat Metab. 2022 Jun;4(6):672-682. doi: 10.1038/s42255-022-00584-y. Epub 2022 Jun 20. PubMed |
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