3XFlag pCMV5-TOPO TAZ WT Citations (12)
Originally described in: TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL Nat Cell Biol. 2008 Jul . 10(7):837-48. PubMed Journal
Articles Citing 3XFlag pCMV5-TOPO TAZ WT
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Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor. Paramasivam M, Sarkeshik A, Yates JR 3rd, Fernandes MJ, McCollum D. Mol Biol Cell. 2011 Oct;22(19):3725-33. doi: 10.1091/mbc.E11-04-0300. Epub 2011 Aug 10. PubMed |
ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, Herr R, Brabletz S, Stemmler MP, Brabletz T. Nat Commun. 2016 Feb 15;7:10498. doi: 10.1038/ncomms10498. PubMed |
The Hippo effector TAZ (WWTR1) transforms myoblasts and its abundance is associated with reduced survival in embryonal rhabdomyosarcoma. Mohamed A, Sun C, De Mello V, Selfe J, Missiaglia E, Shipley J, Murray GI, Zammit PS, Wackerhage H. J Pathol. 2016 May 17. doi: 10.1002/path.4745. PubMed |
TGFbeta-TAZ/SRF signalling regulates vascular smooth muscle cell differentiation. Pagiatakis C, Sun D, Tobin SW, Miyake T, McDermott JC. FEBS J. 2017 Jun;284(11):1644-1656. doi: 10.1111/febs.14070. Epub 2017 Apr 20. PubMed |
YAP regulates cell mechanics by controlling focal adhesion assembly. Nardone G, Oliver-De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, Pesl M, Caluori G, Pagliari S, Martino F, Maceckova Z, Hajduch M, Sanz-Garcia A, Pugno NM, Stokin GB, Forte G. Nat Commun. 2017 May 15;8:15321. doi: 10.1038/ncomms15321. PubMed |
Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function. Sun C, De Mello V, Mohamed A, Ortuste Quiroga HP, Garcia-Munoz A, Al Bloshi A, Tremblay AM, von Kriegsheim A, Collie-Duguid E, Vargesson N, Matallanas D, Wackerhage H, Zammit PS. Stem Cells. 2017 Aug;35(8):1958-1972. doi: 10.1002/stem.2652. Epub 2017 Jun 27. PubMed |
Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner. Lee Y, Kim NH, Cho ES, Yang JH, Cha YH, Kang HE, Yun JS, Cho SB, Lee SH, Paclikova P, Radaszkiewicz TW, Bryja V, Kang CG, Yuk YS, Cha SY, Kim SY, Kim HS, Yook JI. Nat Commun. 2018 Jun 12;9(1):2301. doi: 10.1038/s41467-018-04757-w. PubMed |
TNF-alpha-Induced YAP/TAZ Activity Mediates Leukocyte-Endothelial Adhesion by Regulating VCAM1 Expression in Endothelial Cells. Choi HJ, Kim NE, Kim BM, Seo M, Heo JH. Int J Mol Sci. 2018 Nov 1;19(11). pii: ijms19113428. doi: 10.3390/ijms19113428. PubMed |
POPX2 is a novel LATS phosphatase that regulates the Hippo pathway. Rahmat MB, Zhang S, Koh CG. Oncotarget. 2019 Feb 19;10(15):1525-1538. doi: 10.18632/oncotarget.26689. eCollection 2019 Feb 19. PubMed |
A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis. Hoj JP, Mayro B, Pendergast AM. Cell Rep. 2019 Dec 10;29(11):3421-3434.e8. doi: 10.1016/j.celrep.2019.11.018. PubMed |
TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states. Xu S, Liu Y, Hu R, Wang M, Stohr O, Xiong Y, Chen L, Kang H, Zheng L, Cai S, He L, Wang C, Copps KD, White MF, Miao J. Elife. 2021 Oct 8;10. pii: 57462. doi: 10.7554/eLife.57462. PubMed |
Sirtuin 5-mediated deacetylation of TAZ at K54 promotes melanoma development. Kim G, Bhattarai PY, Lim SC, Lee KY, Choi HS. Cell Oncol (Dordr). 2023 Dec 19. doi: 10.1007/s13402-023-00910-w. PubMed |
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