7TFP Citations (39)
Originally described in: Lentiviral vectors to probe and manipulate the wnt signaling pathway.Fuerer C, Nusse R PLoS One. 2010 . 5(2):e9370. PubMed Journal
Articles Citing 7TFP
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| Phytochemicals attenuating aberrant activation of beta-catenin in cancer cells. Wang D, Wise ML, Li F, Dey M. PLoS One. 2012;7(12):e50508. doi: 10.1371/journal.pone.0050508. Epub 2012 Dec 3. PubMed |
Optogenetic protein clustering and signaling activation in mammalian cells.
Bugaj LJ, Choksi AT, Mesuda CK, Kane RS, Schaffer DV.
Nat Methods. 2013 Feb 3. doi: 10.1038/nmeth.2360.
PubMed
Associated Plasmids |
| LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/beta-Catenin Signaling. Scannell CA, Pedersen EA, Mosher JT, Krook MA, Nicholls LA, Wilky BA, Loeb DM, Lawlor ER. Front Oncol. 2013 Apr 15;3:81. doi: 10.3389/fonc.2013.00081. eCollection 2013. PubMed |
| Evidence for tankyrases as antineoplastic targets in lung cancer. Busch AM, Johnson KC, Stan RV, Sanglikar A, Ahmed Y, Dmitrovsky E, Freemantle SJ. BMC Cancer. 2013 Apr 28;13:211. doi: 10.1186/1471-2407-13-211. PubMed |
| Sirtuin1 (Sirt1) promotes cortical bone formation by preventing beta-catenin sequestration by FoxO transcription factors in osteoblast progenitors. Iyer S, Han L, Bartell SM, Kim HN, Gubrij I, de Cabo R, O'Brien CA, Manolagas SC, Almeida M. J Biol Chem. 2014 Aug 29;289(35):24069-78. doi: 10.1074/jbc.M114.561803. Epub 2014 Jul 7. PubMed |
| Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance. Choi PS, Li Y, Felsher DW. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3316-24. doi: 10.1073/pnas.1406123111. Epub 2014 Jul 28. PubMed |
| Cell-based assay for low- and high-scale screening of the Wnt/beta-catenin signaling modulators. Mazur M, Bujak A, Matloka M, Janowska S, Gunerka P, Bojarski L, Stanczak A, Klejman A, Bednarek A, Lamparska-Przybysz M, Wieczorek M. Anal Biochem. 2015 Apr 15;475:56-67. doi: 10.1016/j.ab.2015.01.016. Epub 2015 Feb 7. PubMed |
| Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering. Bugaj LJ, Spelke DP, Mesuda CK, Varedi M, Kane RS, Schaffer DV. Nat Commun. 2015 Apr 22;6:6898. doi: 10.1038/ncomms7898. PubMed |
| Inhibition of beta-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells. Chatterjee SS, Saj A, Gocha T, Murphy M, Gonsalves FC, Zhang X, Hayward P, Akgol Oksuz B, Shen SS, Madar A, Martinez Arias A, DasGupta R. J Cell Biol. 2015 Oct 12;211(1):39-51. doi: 10.1083/jcb.201503017. PubMed |
| Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering beta-catenin degradation. Cott C, Thuenauer R, Landi A, Kuhn K, Juillot S, Imberty A, Madl J, Eierhoff T, Romer W. Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1106-18. doi: 10.1016/j.bbamcr.2016.02.004. Epub 2016 Feb 6. PubMed |
| MEK and TAK1 Regulate Apoptosis in Colon Cancer Cells with KRAS-Dependent Activation of Proinflammatory Signaling. McNew KL, Whipple WJ, Mehta AK, Grant TJ, Ray L, Kenny C, Singh A. Mol Cancer Res. 2016 Dec;14(12):1204-1216. Epub 2016 Sep 21. PubMed |
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in beta-Catenin-Active Cancers.
Rosenbluh J, Mercer J, Shrestha Y, Oliver R, Tamayo P, Doench JG, Tirosh I, Piccioni F, Hartenian E, Horn H, Fagbami L, Root DE, Jaffe J, Lage K, Boehm JS, Hahn WC.
Cell Syst. 2016 Sep 28;3(3):302-316.e4. doi: 10.1016/j.cels.2016.09.001.
PubMed
Associated Plasmids |
| Intercellular Coupling of the Cell Cycle and Circadian Clock in Adult Stem Cell Culture. Matsu-Ura T, Dovzhenok A, Aihara E, Rood J, Le H, Ren Y, Rosselot AE, Zhang T, Lee C, Obrietan K, Montrose MH, Lim S, Moore SR, Hong CI. Mol Cell. 2016 Dec 1;64(5):900-912. doi: 10.1016/j.molcel.2016.10.015. Epub 2016 Nov 17. PubMed |
| Inactivation of ABL kinases suppresses non-small cell lung cancer metastasis. Gu JJ, Rouse C, Xu X, Wang J, Onaitis MW, Pendergast AM. JCI Insight. 2016 Dec 22;1(21):e89647. doi: 10.1172/jci.insight.89647. PubMed |
| PS1/gamma-Secretase-Mediated Cadherin Cleavage Induces beta-Catenin Nuclear Translocation and Osteogenic Differentiation of Human Bone Marrow Stromal Cells. Bonfim DC, Dias RB, Fortuna-Costa A, Chicaybam L, Lopes DV, Dutra HS, Borojevic R, Bonamino M, Mermelstein C, Rossi MI. Stem Cells Int. 2016;2016:3865315. doi: 10.1155/2016/3865315. Epub 2016 Dec 8. PubMed |
| Psoriasin has divergent effects on the innate immune responses of murine glial cells. Jansen S, Kress E, Fragoulis A, Wruck CJ, Wolf R, Grotzinger J, Michalek M, Pufe T, Tauber SC, Brandenburg LO. J Neurochem. 2017 Apr;141(1):86-99. doi: 10.1111/jnc.13959. Epub 2017 Feb 27. PubMed |
| An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome. Iefremova V, Manikakis G, Krefft O, Jabali A, Weynans K, Wilkens R, Marsoner F, Brandl B, Muller FJ, Koch P, Ladewig J. Cell Rep. 2017 Apr 4;19(1):50-59. doi: 10.1016/j.celrep.2017.03.047. PubMed |
| A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Tammela T, Sanchez-Rivera FJ, Cetinbas NM, Wu K, Joshi NS, Helenius K, Park Y, Azimi R, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz OH, Xue W, Katajisto P, Bhutkar A, Jacks T. Nature. 2017 May 18;545(7654):355-359. doi: 10.1038/nature22334. Epub 2017 May 10. PubMed |
| Disrupting Interactions Between beta-Catenin and Activating TCFs Reconstitutes Ground State Pluripotency in Mouse Embryonic Stem Cells. Saj A, Chatterjee SS, Zhu B, Cukuroglu E, Gocha T, Zhang X, Goke J, DasGupta R. Stem Cells. 2017 Aug;35(8):1924-1933. doi: 10.1002/stem.2647. Epub 2017 Jun 15. PubMed |
| A simple and scalable hydrogel-based system for culturing protein-producing cells. Li Q, Wang Q, Wang O, Shao K, Lin H, Lei Y. PLoS One. 2018 Jan 2;13(1):e0190364. doi: 10.1371/journal.pone.0190364. eCollection 2018. PubMed |
| Scalable and physiologically relevant microenvironments for human pluripotent stem cell expansion and differentiation. Li Q, Lin H, Du Q, Liu K, Wang O, Evans C, Christian H, Zhang C, Lei Y. Biofabrication. 2018 Feb 1;10(2):025006. doi: 10.1088/1758-5090/aaa6b5. PubMed |
| The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation. Xiong J, Almeida M, O'Brien CA. Bone. 2018 Jul;112:1-9. doi: 10.1016/j.bone.2018.04.001. Epub 2018 Apr 4. PubMed |
| RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Szenker-Ravi E, Altunoglu U, Leushacke M, Bosso-Lefevre C, Khatoo M, Thi Tran H, Naert T, Noelanders R, Hajamohideen A, Beneteau C, de Sousa SB, Karaman B, Latypova X, Basaran S, Yucel EB, Tan TT, Vlaminck L, Nayak SS, Shukla A, Girisha KM, Le Caignec C, Soshnikova N, Uyguner ZO, Vleminckx K, Barker N, Kayserili H, Reversade B. Nature. 2018 May;557(7706):564-569. doi: 10.1038/s41586-018-0118-y. Epub 2018 May 16. PubMed |
| Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes. Guimaraes PPG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CTR, Jacks T, Langer R, Mitchell MJ. J Control Release. 2018 Nov 28;290:75-87. doi: 10.1016/j.jconrel.2018.09.025. Epub 2018 Oct 2. PubMed |
| Desmoglein 2 mutation provokes skeletal muscle actin expression and accumulation at intercalated discs in murine hearts. Kant S, Freytag B, Herzog A, Reich A, Merkel R, Hoffmann B, Krusche CA, Leube RE. J Cell Sci. 2019 Feb 18;132(5). pii: jcs.199612. doi: 10.1242/jcs.199612. PubMed |
| The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy. Skaga E, Skaga IO, Grieg Z, Sandberg CJ, Langmoen IA, Vik-Mo EO. J Cancer Res Clin Oncol. 2019 Jun;145(6):1495-1507. doi: 10.1007/s00432-019-02920-4. Epub 2019 Apr 26. PubMed |
| Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules. Li TM, Coan JP, Krajewski K, Zhang L, Elias JE, Strahl BD, Gozani O, Chua KF. Sci Rep. 2019 Oct 2;9(1):14226. doi: 10.1038/s41598-019-50817-6. PubMed |
| Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer Metastasis. Leibold J, Ruscetti M, Cao Z, Ho YJ, Baslan T, Zou M, Abida W, Feucht J, Han T, Barriga FM, Tsanov KM, Zamechek L, Kulick A, Amor C, Tian S, Rybczyk K, Salgado NR, Sanchez-Rivera FJ, Watson PA, de Stanchina E, Wilkinson JE, Dow LE, Abate-Shen C, Sawyers CL, Lowe SW. Cancer Discov. 2020 Jul;10(7):1038-1057. doi: 10.1158/2159-8290.CD-19-1242. Epub 2020 May 6. PubMed |
| Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling. Tsutsumi N, Mukherjee S, Waghray D, Janda CY, Jude KM, Miao Y, Burg JS, Aduri NG, Kossiakoff AA, Gati C, Garcia KC. Elife. 2020 Aug 7;9. pii: 58464. doi: 10.7554/eLife.58464. PubMed |
| TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis. Chen M, Amado N, Tan J, Reis A, Ge M, Abreu JG, He X. Elife. 2020 Sep 14;9. pii: 56793. doi: 10.7554/eLife.56793. PubMed |
| Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygard S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J. iScience. 2021 Jul 1;24(7):102807. doi: 10.1016/j.isci.2021.102807. eCollection 2021 Jul 23. PubMed |
| Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer. Ma F, Arai S, Wang K, Calagua C, Yuan AR, Poluben L, Gu Z, Russo JW, Einstein DJ, Ye H, He MX, Liu Y, Van Allen E, Sowalsky AG, Bhasin MK, Yuan X, Balk SP. Cancer Res. 2022 Apr 15;82(8):1518-1533. doi: 10.1158/0008-5472.CAN-21-1807. PubMed |
| A novel beta-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer. Tanton H, Sewastianik T, Seo HS, Remillard D, Pierre RS, Bala P, Aitymbayev D, Dennis P, Adler K, Geffken E, Yeoh Z, Vangos N, Garbicz F, Scott D, Sethi N, Bradner J, Dhe-Paganon S, Carrasco RD. Sci Adv. 2022 Apr 29;8(17):eabm3108. doi: 10.1126/sciadv.abm3108. Epub 2022 Apr 29. PubMed |
| Wnt/BMP Mediated Metabolic Reprogramming Preserves Multipotency of Neural Crest-Like Stem Cells. Mehrotra P, Ikhapoh I, Lei P, Tseropoulos G, Zhang Y, Wang J, Liu S, Bronner ME, Andreadis ST. Stem Cells. 2023 Mar 17;41(3):287-305. doi: 10.1093/stmcls/sxad001. PubMed |
| SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions. Pilat JM, Brown RE, Chen Z, Berle NJ, Othon AP, Washington MK, Anant SA, Kurokawa S, Ng VH, Thompson JJ, Jacobse J, Goettel JA, Lee E, Choksi YA, Lau KS, Short SP, Williams CS. J Clin Invest. 2023 Jul 3;133(13):e165988. doi: 10.1172/JCI165988. PubMed |
| Optogenetic control of Wnt signaling models cell-intrinsic embryogenic patterning using 2D human pluripotent stem cell culture. Repina NA, Johnson HJ, Bao X, Zimmermann JA, Joy DA, Bi SZ, Kane RS, Schaffer DV. Development. 2023 Jul 15;150(14):dev201386. doi: 10.1242/dev.201386. Epub 2023 Jul 26. PubMed |
| R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling. Ter Steege EJ, Doornbos LW, Haughton PD, van Diest PJ, Hilkens J, Derksen PWB, Bakker ERM. Cancer Lett. 2023 Aug 1;568:216301. doi: 10.1016/j.canlet.2023.216301. Epub 2023 Jul 3. PubMed |
| An Efficient and Cost-Effective Approach to Generate Functional Human Inducible Pluripotent Stem Cell-Derived Astrocytes. Gonzalez H, Narasipura SD, Shull T, Shetty A, Teppen TL, Naqib A, Al-Harthi L. Cells. 2023 Sep 26;12(19):2357. doi: 10.3390/cells12192357. PubMed |
| GSK3 inhibition reduces ECM production and prevents age-related macular degeneration-like pathology. DiCesare SM, Ortega AJ, Collier GE, Daniel S, Thompson KN, McCoy MK, Posner BA, Hulleman JD. bioRxiv [Preprint]. 2023 Dec 15:2023.12.14.571757. doi: 10.1101/2023.12.14.571757. PubMed |
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