p3xFLAG-CMV10-hFIP200 Citations (13)
Originally described in: FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N J Cell Biol. 2008 May 5. 181(3):497-510. PubMed Journal
Articles Citing p3xFLAG-CMV10-hFIP200
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Inhibition of autophagy via p53-mediated disruption of ULK1 in a SCA7 polyglutamine disease model. Yu X, Munoz-Alarcon A, Ajayi A, Webling KE, Steinhof A, Langel U, Strom AL. J Mol Neurosci. 2013 Jul;50(3):586-99. doi: 10.1007/s12031-013-0012-x. Epub 2013 Apr 18. PubMed |
MiR-20a and miR-20b negatively regulate autophagy by targeting RB1CC1/FIP200 in breast cancer cells. Li S, Qiang Q, Shan H, Shi M, Gan G, Ma F, Chen B. Life Sci. 2016 Feb 15;147:143-52. doi: 10.1016/j.lfs.2016.01.044. Epub 2016 Jan 29. PubMed |
The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway. Sullivan PM, Zhou X, Robins AM, Paushter DH, Kim D, Smolka MB, Hu F. Acta Neuropathol Commun. 2016 May 18;4(1):51. doi: 10.1186/s40478-016-0324-5. PubMed |
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy. Webster CP, Smith EF, Bauer CS, Moller A, Hautbergue GM, Ferraiuolo L, Myszczynska MA, Higginbottom A, Walsh MJ, Whitworth AJ, Kaspar BK, Meyer K, Shaw PJ, Grierson AJ, De Vos KJ. EMBO J. 2016 Jun 22. pii: e201694401. PubMed |
LC3-association with the parasitophorous vacuole membrane of Plasmodium berghei liver stages follows a noncanonical autophagy pathway. Wacker R, Eickel N, Schmuckli-Maurer J, Annoura T, Niklaus L, Khan SM, Guan JL, Heussler VT. Cell Microbiol. 2017 Jun 1. doi: 10.1111/cmi.12754. PubMed |
Structural and functional analysis of the GABARAP interaction motif (GIM). Rogov VV, Stolz A, Ravichandran AC, Rios-Szwed DO, Suzuki H, Kniss A, Lohr F, Wakatsuki S, Dotsch V, Dikic I, Dobson RC, McEwan DG. EMBO Rep. 2017 Aug;18(8):1382-1396. doi: 10.15252/embr.201643587. Epub 2017 Jun 27. PubMed |
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis. Smith MD, Harley ME, Kemp AJ, Wills J, Lee M, Arends M, von Kriegsheim A, Behrends C, Wilkinson S. Dev Cell. 2018 Jan 22;44(2):217-232.e11. doi: 10.1016/j.devcel.2017.11.024. Epub 2017 Dec 28. PubMed |
MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process. Colecchia D, Dapporto F, Tronnolone S, Salvini L, Chiariello M. J Biol Chem. 2018 Oct 12;293(41):15962-15976. doi: 10.1074/jbc.RA118.002527. Epub 2018 Aug 21. PubMed |
Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.
Vargas JNS, Wang C, Bunker E, Hao L, Maric D, Schiavo G, Randow F, Youle RJ.
Mol Cell. 2019 Apr 18;74(2):347-362.e6. doi: 10.1016/j.molcel.2019.02.010. Epub 2019 Mar 7.
PubMed
Associated Plasmids |
miR-10a as a therapeutic target and predictive biomarker for MDM2 inhibition in acute myeloid leukemia. Vu TT, Stolzel F, Wang KW, Rollig C, Tursky ML, Molloy TJ, Ma DD. Leukemia. 2020 Dec 1. pii: 10.1038/s41375-020-01095-z. doi: 10.1038/s41375-020-01095-z. PubMed |
The ERK1/2-ATG13-FIP200 signaling cascade is required for autophagy induction to protect renal cells from hypoglycemia-induced cell death. Guo W, Wang Q, Pan S, Li J, Wang Y, Shu Y, Chen J, Wang Q, Zhang S, Zhang X, Yue J. J Cell Physiol. 2021 Oct;236(10):6932-6947. doi: 10.1002/jcp.30354. Epub 2021 Mar 8. PubMed |
FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates. Schlutermann D, Berleth N, Deitersen J, Wallot-Hieke N, Friesen O, Wu W, Stuhldreier F, Sun Y, Berning L, Friedrich A, Mendiburo MJ, Peter C, Wiek C, Hanenberg H, Stefanski A, Stuhler K, Stork B. Sci Rep. 2021 Jul 5;11(1):13863. doi: 10.1038/s41598-021-92408-4. PubMed |
Autophagy dictates sensitivity to PRMT5 inhibitor in breast cancer. Brobbey C, Yin S, Liu L, Ball LE, Howe PH, Delaney JR, Gan W. Sci Rep. 2023 Jul 3;13(1):10752. doi: 10.1038/s41598-023-37706-9. PubMed |
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