pCMV-HA-UTX Citations (9)

Originally described in: UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.
Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, Issaeva I, Canaani E, Salcini AE, Helin K Nature. 2007 Oct 11. 449(7163):731-4. PubMed Journal

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Articles Citing pCMV-HA-UTX

Articles
Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1alpha at chromatin. Boros J, Arnoult N, Stroobant V, Collet JF, Decottignies A. Mol Cell Biol. 2014 Oct 1;34(19):3662-74. doi: 10.1128/MCB.00205-14. Epub 2014 Jul 21. PubMed
Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease. Majumder S, Thieme K, Batchu SN, Alghamdi TA, Bowskill BB, Kabir MG, Liu Y, Advani SL, White KE, Geldenhuys L, Tennankore KK, Poyah P, Siddiqi FS, Advani A. J Clin Invest. 2018 Jan 2;128(1):483-499. doi: 10.1172/JCI95946. Epub 2017 Dec 11. PubMed
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights AJ, Pardo M, Yu L, Choudhary JS, Metzakopian E, Iyer V, Yun H, Park N, Varela I, Bautista R, Collord G, Dovey O, Garyfallos DA, De Braekeleer E, Kondo S, Cooper J, Gottgens B, Bullinger L, Northcott PA, Adams D, Vassiliou GS, Huntly BJP. Nat Genet. 2018 Jun;50(6):883-894. doi: 10.1038/s41588-018-0114-z. Epub 2018 May 7. PubMed
Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts. Perrigue PM, Rakoczy M, Pawlicka KP, Belter A, Giel-Pietraszuk M, Naskret-Barciszewska M, Barciszewski J, Figlerowicz M. Cancers (Basel). 2020 Jun 30;12(7). pii: cancers12071745. doi: 10.3390/cancers12071745. PubMed
CHARGE syndrome and related disorders: A mechanistic link. Ufartes R, Grun R, Salinas G, Sitte M, Kahl F, Wong MTY, van Ravenswaaij-Arts CMA, Pauli S. Hum Mol Genet. 2021 Jul 6. pii: 6316234. doi: 10.1093/hmg/ddab183. PubMed
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition. Boila LD, Ghosh S, Bandyopadhyay SK, Jin L, Murison A, Zeng AGX, Shaikh W, Bhowmik S, Muddineni SSNA, Biswas M, Sinha S, Chatterjee SS, Mbong N, Gan OI, Bose A, Chakraborty S, Arruda A, Kennedy JA, Mitchell A, Lechman ER, Banerjee D, Milyavsky M, Minden MD, Dick JE, Sengupta A. Leukemia. 2023 Jan 31. doi: 10.1038/s41375-023-01833-z. PubMed
Differential Occupancy and Regulatory Interactions of KDM6A in Bladder Cell Lines. Ozden-Yilmaz G, Savas B, Bursali A, Eray A, Aribas A, Senturk S, Karaca E, Karakulah G, Erkek-Ozhan S. Cells. 2023 Mar 8;12(6):836. doi: 10.3390/cells12060836. PubMed
Alternative mRNA Splicing Controls the Functions of the Histone H3K27 Demethylase UTX/KDM6A. Fotouhi O, Nizamuddin S, Falk S, Schilling O, Knuchel-Clarke R, Biniossek ML, Timmers HTM. Cancers (Basel). 2023 Jun 8;15(12):3117. doi: 10.3390/cancers15123117. PubMed
Repressive H3K27me3 drives hyperglycemia-induced oxidative and inflammatory transcriptional programs in human endothelium. Sanchez-Ceinos J, Hussain S, Khan AW, Zhang L, Almahmeed W, Pernow J, Cosentino F. Cardiovasc Diabetol. 2024 Apr 5;23(1):122. doi: 10.1186/s12933-024-02196-0. PubMed

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