pCI NL4-3 Nef-HA-WT Citations (4)

Originally described in: HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell.
Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC Nature. 2001 Apr 12. 410(6830):834-8. PubMed Journal

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Articles Citing pCI NL4-3 Nef-HA-WT

Articles
Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses. McNamara RP, Costantini LM, Myers TA, Schouest B, Maness NJ, Griffith JD, Damania BA, MacLean AG, Dittmer DP. MBio. 2018 Feb 6;9(1). pii: mBio.02344-17. doi: 10.1128/mBio.02344-17. PubMed
A Structure-Informed Atlas of Human-Virus Interactions. Lasso G, Mayer SV, Winkelmann ER, Chu T, Elliot O, Patino-Galindo JA, Park K, Rabadan R, Honig B, Shapira SD. Cell. 2019 Sep 5;178(6):1526-1541.e16. doi: 10.1016/j.cell.2019.08.005. Epub 2019 Aug 29. PubMed
HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner. Castro-Gonzalez S, Shi Y, Colomer-Lluch M, Song Y, Mowery K, Almodovar S, Bansal A, Kirchhoff F, Sparrer K, Liang C, Serra-Moreno R. Autophagy. 2021 Feb;17(2):553-577. doi: 10.1080/15548627.2020.1725401. Epub 2020 Feb 25. PubMed
Residues T48 and A49 in HIV-1 NL4-3 Nef are responsible for the counteraction of autophagy initiation, which prevents the ubiquitin-dependent degradation of Gag through autophagosomes. Castro-Gonzalez S, Chen Y, Benjamin J, Shi Y, Serra-Moreno R. Retrovirology. 2021 Oct 28;18(1):33. doi: 10.1186/s12977-021-00576-y. PubMed

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