pLKO.1 hygro Citations (59)
Originally described in: empty vectorUnpublished
Articles Citing pLKO.1 hygro
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| Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Cell. 2011 Nov 23;147(5):1066-79. doi: 10.1016/j.cell.2011.10.039. PubMed |
| Separase-dependent cleavage of pericentrin B is necessary and sufficient for centriole disengagement during mitosis. Lee K, Rhee K. Cell Cycle. 2012 Jul 1;11(13):2476-85. doi: 10.4161/cc.20878. Epub 2012 Jul 1. PubMed |
| Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic beta cell death. Bartolome A, Guillen C, Benito M. Autophagy. 2012 Dec;8(12):1757-68. doi: 10.4161/auto.21994. Epub 2012 Sep 5. PubMed |
| The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis. Evangelou K, Bartkova J, Kotsinas A, Pateras IS, Liontos M, Velimezi G, Kosar M, Liloglou T, Trougakos IP, Dyrskjot L, Andersen CL, Papaioannou M, Drosos Y, Papafotiou G, Hodny Z, Sosa-Pineda B, Wu XR, Klinakis A, Orntoft T, Lukas J, Bartek J, Gorgoulis VG. Cell Death Differ. 2013 Nov;20(11):1485-97. doi: 10.1038/cdd.2013.76. Epub 2013 Jul 12. PubMed |
| TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer. Busch S, Acar A, Magnusson Y, Gregersson P, Ryden L, Landberg G. Oncogene. 2015 Jan 2;34(1):27-38. doi: 10.1038/onc.2013.527. Epub 2013 Dec 16. PubMed |
| Regulation of mitochondrial function and cellular energy metabolism by protein kinase C-lambda/iota: a novel mode of balancing pluripotency. Mahato B, Home P, Rajendran G, Paul A, Saha B, Ganguly A, Ray S, Roy N, Swerdlow RH, Paul S. Stem Cells. 2014 Nov;32(11):2880-92. doi: 10.1002/stem.1817. PubMed |
| Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. Bohnsack RN, Warejcka DJ, Wang L, Gillespie SR, Bernstein AM, Twining SS, Dahms NM. Invest Ophthalmol Vis Sci. 2014 Oct 30;55(12):7697-708. doi: 10.1167/iovs.14-15179. PubMed |
| Evidence of an oncogenic role of aberrant TOX activation in cutaneous T-cell lymphoma. Huang Y, Su MW, Jiang X, Zhou Y. Blood. 2015 Feb 26;125(9):1435-43. doi: 10.1182/blood-2014-05-571778. Epub 2014 Dec 29. PubMed |
| Loss of TGFbeta Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance. Busch S, Sims AH, Stal O, Ferno M, Landberg G. Cancer Res. 2015 Apr 1;75(7):1457-69. doi: 10.1158/0008-5472.CAN-14-1583. PubMed |
| Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach. Chari R, Mali P, Moosburner M, Church GM. Nat Methods. 2015 Sep;12(9):823-6. doi: 10.1038/nmeth.3473. Epub 2015 Jul 13. PubMed |
| Role of Erk1/2 Signaling in the Regulation of Neutrophil Versus Monocyte Development in Response to G-CSF and M-CSF. Hu N, Qiu Y, Dong F. J Biol Chem. 2015 Oct 2;290(40):24561-73. doi: 10.1074/jbc.M115.668871. Epub 2015 Aug 20. PubMed |
| MiR-29-mediated elastin down-regulation contributes to inorganic phosphorus-induced osteoblastic differentiation in vascular smooth muscle cells. Sudo R, Sato F, Azechi T, Wachi H. Genes Cells. 2015 Dec;20(12):1077-87. doi: 10.1111/gtc.12311. Epub 2015 Nov 27. PubMed |
| Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, Karakhanyan A, Pang Z, Fu XD. Nat Neurosci. 2016 Jun;19(6):807-15. doi: 10.1038/nn.4297. Epub 2016 Apr 25. PubMed |
| The metabolic co-regulator PGC1alpha suppresses prostate cancer metastasis. Torrano V, Valcarcel-Jimenez L, Cortazar AR, Liu X, Urosevic J, Castillo-Martin M, Fernandez-Ruiz S, Morciano G, Caro-Maldonado A, Guiu M, Zuniga-Garcia P, Graupera M, Bellmunt A, Pandya P, Lorente M, Martin-Martin N, Sutherland JD, Sanchez-Mosquera P, Bozal-Basterra L, Zabala-Letona A, Arruabarrena-Aristorena A, Berenguer A, Embade N, Ugalde-Olano A, Lacasa-Viscasillas I, Loizaga-Iriarte A, Unda-Urzaiz M, Schultz N, Aransay AM, Sanz-Moreno V, Barrio R, Velasco G, Pinton P, Cordon-Cardo C, Locasale JW, Gomis RR, Carracedo A. Nat Cell Biol. 2016 Jun;18(6):645-656. doi: 10.1038/ncb3357. Epub 2016 May 23. PubMed |
| TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy. Garcia-Aguilar A, Guillen C, Nellist M, Bartolome A, Benito M. Biochim Biophys Acta. 2016 Nov;1863(11):2658-2667. doi: 10.1016/j.bbamcr.2016.08.006. Epub 2016 Aug 16. PubMed |
| MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines. Fenger JM, Roberts RD, Iwenofu OH, Bear MD, Zhang X, Couto JI, Modiano JF, Kisseberth WC, London CA. BMC Cancer. 2016 Oct 10;16(1):784. PubMed |
| PRC2 is dispensable for HOTAIR-mediated transcriptional repression. Portoso M, Ragazzini R, Brencic Z, Moiani A, Michaud A, Vassilev I, Wassef M, Servant N, Sargueil B, Margueron R. EMBO J. 2017 Apr 13;36(8):981-994. doi: 10.15252/embj.201695335. Epub 2017 Feb 6. PubMed |
| Mitotic progression following DNA damage enables pattern recognition within micronuclei. Harding SM, Benci JL, Irianto J, Discher DE, Minn AJ, Greenberg RA. Nature. 2017 Aug 24;548(7668):466-470. doi: 10.1038/nature23470. Epub 2017 Jul 31. PubMed |
| Hemidesmosomal linker proteins regulate cell motility, invasion and tumorigenicity in oral squamous cell carcinoma derived cells. Chaudhari PR, Charles SE, D'Souza ZC, Vaidya MM. Exp Cell Res. 2017 Nov 15;360(2):125-137. doi: 10.1016/j.yexcr.2017.08.034. Epub 2017 Sep 1. PubMed |
| Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-beta signaling. Yu Y, Gu S, Li W, Sun C, Chen F, Xiao M, Wang L, Xu D, Li Y, Ding C, Xia Z, Li Y, Ye S, Xu P, Zhao B, Qin J, Chen YG, Lin X, Feng XH. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10113-10118. doi: 10.1073/pnas.1705755114. Epub 2017 Sep 5. PubMed |
| Lysyl Oxidase Enhances the Deposition of Tropoelastin through the Catalysis of Tropoelastin Molecules on the Cell Surface. Sato F, Seino-Sudo R, Okada M, Sakai H, Yumoto T, Wachi H. Biol Pharm Bull. 2017;40(10):1646-1653. doi: 10.1248/bpb.b17-00027. PubMed |
| Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1. Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, Zhang S, Gao H, Wang P, Zhang Z, Luo J, Li Z. Autophagy. 2018;14(2):336-346. doi: 10.1080/15548627.2017.1405187. Epub 2018 Jan 29. PubMed |
| RAP2 mediates mechanoresponses of the Hippo pathway. Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL. Nature. 2018 Aug;560(7720):655-660. doi: 10.1038/s41586-018-0444-0. Epub 2018 Aug 22. PubMed |
| Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST). Burkholder NT, Mayfield JE, Yu X, Irani S, Arce DK, Jiang F, Matthews WL, Xue Y, Zhang YJ. J Biol Chem. 2018 Oct 26;293(43):16851-16861. doi: 10.1074/jbc.RA118.004722. Epub 2018 Sep 14. PubMed |
| Role of PDGF receptor-alpha during human cytomegalovirus entry into fibroblasts. Wu K, Oberstein A, Wang W, Shenk T. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9889-E9898. doi: 10.1073/pnas.1806305115. Epub 2018 Oct 1. PubMed |
| Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer. Valcarcel-Jimenez L, Macchia A, Martin-Martin N, Cortazar AR, Schaub-Clerigue A, Pujana-Vaquerizo M, Fernandez-Ruiz S, Lacasa-Viscasillas I, Santos-Martin A, Loizaga-Iriarte A, Unda-Urzaiz M, Hermanova I, Astobiza I, Graupera M, Starkova J, Sutherland J, Barrio R, Aransay AM, Carracedo A, Torrano V. Cell Death Dis. 2018 Oct 11;9(10):1041. doi: 10.1038/s41419-018-1096-6. PubMed |
| L1 drives IFN in senescent cells and promotes age-associated inflammation. De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beausejour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM. Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9. Epub 2019 Feb 6. PubMed |
| Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma. Liu J, Jiang W, Zhao K, Wang H, Zhou T, Bai W, Wang X, Zhao T, Huang C, Gao S, Qin T, Yu W, Yang B, Li X, Fu D, Tan W, Yang S, Ren H, Hao J. J Exp Med. 2019 Mar 4;216(3):656-673. doi: 10.1084/jem.20180749. Epub 2019 Feb 7. PubMed |
| SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, Yang JN, Mao Z, Manta B, Dang W, Zhang Z, Vijg J, Wolfe A, Moody K, Kennedy BK, Bohmann D, Gladyshev VN, Seluanov A, Gorbunova V. Cell. 2019 Apr 18;177(3):622-638.e22. doi: 10.1016/j.cell.2019.03.043. PubMed |
| Co-occurring Alterations in the RAS-MAPK Pathway Limit Response to MET Inhibitor Treatment in MET Exon 14 Skipping Mutation-Positive Lung Cancer. Rotow JK, Gui P, Wu W, Raymond VM, Lanman RB, Kaye FJ, Peled N, Fece de la Cruz F, Nadres B, Corcoran RB, Yeh I, Bastian BC, Starostik P, Newsom K, Olivas VR, Wolff AM, Fraser JS, Collisson EA, McCoach CE, Camidge DR, Pacheco J, Bazhenova L, Li T, Bivona TG, Blakely CM. Clin Cancer Res. 2020 Jan 15;26(2):439-449. doi: 10.1158/1078-0432.CCR-19-1667. Epub 2019 Sep 23. PubMed |
| Essential role of glucokinase in the protection of pancreatic beta cells to the glucose energetic status. Marques P, Kamitz A, Bartolome A, Burillo J, Martinez H, Jimenez B, Fernandez-Rhodes M, Guillen C, Benito M. Cell Death Discov. 2019 Sep 30;5:138. doi: 10.1038/s41420-019-0219-x. eCollection 2019. PubMed |
| Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion. Chen J, Ananthanarayanan B, Springer KS, Wolf KJ, Sheyman SM, Tran VD, Kumar S. Cancer Res. 2020 Jan 1;80(1):69-78. doi: 10.1158/0008-5472.CAN-19-1237. Epub 2019 Oct 22. PubMed |
| STING Restricts oHSV Replication and Spread in Resistant MPNSTs but Is Dispensable for Basal IFN-Stimulated Gene Upregulation. Lee JM, Ghonime MG, Cassady KA. Mol Ther Oncolytics. 2019 Sep 16;15:91-100. doi: 10.1016/j.omto.2019.09.001. eCollection 2019 Dec 20. PubMed |
| APOBEC3A is a prominent cytidine deaminase in breast cancer. Cortez LM, Brown AL, Dennis MA, Collins CD, Brown AJ, Mitchell D, Mertz TM, Roberts SA. PLoS Genet. 2019 Dec 16;15(12):e1008545. doi: 10.1371/journal.pgen.1008545. eCollection 2019 Dec. PubMed |
| The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. Saliakoura M, Reynoso-Moreno I, Pozzato C, Rossi Sebastiano M, Galie M, Gertsch J, Konstantinidou G. Oncogene. 2020 Apr;39(14):2948-2960. doi: 10.1038/s41388-020-1196-5. Epub 2020 Feb 7. PubMed |
| Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression. Liu J, Zhang C, Wu H, Sun XX, Li Y, Huang S, Yue X, Lu SE, Shen Z, Su X, White E, Haffty BG, Hu W, Feng Z. J Clin Invest. 2020 Jun 1;130(6):3253-3269. doi: 10.1172/JCI132876. PubMed |
| CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. Oguri Y, Shinoda K, Kim H, Alba DL, Bolus WR, Wang Q, Brown Z, Pradhan RN, Tajima K, Yoneshiro T, Ikeda K, Chen Y, Cheang RT, Tsujino K, Kim CR, Greiner VJ, Datta R, Yang CD, Atabai K, McManus MT, Koliwad SK, Spiegelman BM, Kajimura S. Cell. 2020 Aug 6;182(3):563-577.e20. doi: 10.1016/j.cell.2020.06.021. Epub 2020 Jul 1. PubMed |
| Macrophage migration inhibitory factor inhibition as a novel therapeutic approach against triple-negative breast cancer. Charan M, Das S, Mishra S, Chatterjee N, Varikuti S, Kaul K, Misri S, Ahirwar DK, Satoskar AR, Ganju RK. Cell Death Dis. 2020 Sep 17;11(9):774. doi: 10.1038/s41419-020-02992-y. PubMed |
| PARP1 and PRC2 double deficiency promotes BRCA-proficient breast cancer growth by modification of the tumor microenvironment. Yang AY, Choi EB, So Park M, Kim SK, Park MS, Kim MY. FEBS J. 2021 May;288(9):2888-2910. doi: 10.1111/febs.15636. Epub 2020 Dec 2. PubMed |
| A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity. Perrin-Cocon L, Vidalain PO, Jacquemin C, Aublin-Gex A, Olmstead K, Panthu B, Rautureau GJP, Andre P, Nyczka P, Hutt MT, Amoedo N, Rossignol R, Filipp FV, Lotteau V, Diaz O. Commun Biol. 2021 Feb 16;4(1):217. doi: 10.1038/s42003-021-01749-3. PubMed |
| Naked mole rat TRF1 safeguards glycolytic capacity and telomere replication under low oxygen. Augereau A, Mariotti M, Pousse M, Filipponi D, Libert F, Beck B, Gorbunova V, Gilson E, Gladyshev VN. Sci Adv. 2021 Feb 19;7(8). pii: 7/8/eabe0174. doi: 10.1126/sciadv.abe0174. Print 2021 Feb. PubMed |
| PRMT5 Enables Robust STAT3 Activation via Arginine Symmetric Dimethylation of SMAD7. Cai C, Gu S, Yu Y, Zhu Y, Zhang H, Yuan B, Shen L, Yang B, Feng XH. Adv Sci (Weinh). 2021 Feb 24;8(10):2003047. doi: 10.1002/advs.202003047. eCollection 2021 May. PubMed |
| Gain-of-function p53(R172H) mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy. Siolas D, Vucic E, Kurz E, Hajdu C, Bar-Sagi D. Cell Rep. 2021 Aug 24;36(8):109578. doi: 10.1016/j.celrep.2021.109578. PubMed |
| Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy. Yang D, Wu X, Wang W, Zhou Y, Wang Z. Adv Sci (Weinh). 2022 Jan;9(3):e2102568. doi: 10.1002/advs.202102568. Epub 2021 Nov 16. PubMed |
| Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing. Segelle A, Nunez-Alvarez Y, Oldfield AJ, Webb KM, Voigt P, Luco RF. Cell Rep. 2022 Feb 15;38(7):110357. doi: 10.1016/j.celrep.2022.110357. PubMed |
| Purification of mammalian telomeric DNA for single-molecule analysis. Mazzucco G, Huda A, Galli M, Zanella E, Doksani Y. Nat Protoc. 2022 Jun;17(6):1444-1467. doi: 10.1038/s41596-022-00684-9. Epub 2022 Apr 8. PubMed |
| Post-translational control of beige fat biogenesis by PRDM16 stabilization. Wang Q, Li H, Tajima K, Verkerke ARP, Taxin ZH, Hou Z, Cole JB, Li F, Wong J, Abe I, Pradhan RN, Yamamuro T, Yoneshiro T, Hirschhorn JN, Kajimura S. Nature. 2022 Sep;609(7925):151-158. doi: 10.1038/s41586-022-05067-4. Epub 2022 Aug 17. PubMed |
| Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex. Tsai CW, Rodriguez MX, Van Keuren AM, Phillips CB, Shushunov HM, Lee JE, Garcia AM, Ambardekar AV, Cleveland JC Jr, Reisz JA, Proenza C, Chatfield KC, Tsai MF. Mol Cell. 2022 Oct 6;82(19):3661-3676.e8. doi: 10.1016/j.molcel.2022.09.006. PubMed |
| The ubiquitin ligase TRIM21 regulates mutant p53 accumulation and gain of function in cancer. Liu J, Zhang C, Xu D, Zhang T, Chang CY, Wang J, Liu J, Zhang L, Haffty BG, Zong WX, Hu W, Feng Z. J Clin Invest. 2023 Mar 15;133(6):e164354. doi: 10.1172/JCI164354. PubMed |
| Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells. Cottrell KA, Ryu S, Torres LS, Schab AM, Weber JD. bioRxiv. 2023 Mar 1:2023.02.27.530307. doi: 10.1101/2023.02.27.530307. Preprint. PubMed |
| Lethal giant larvae gene family ( Llgl1 and Llgl2 ) functions as a tumor suppressor in mouse skin epidermis. Bii VM, Rudoy D, Klezovitch O, Vasioukhin V. bioRxiv. 2023 Mar 8:2023.03.06.531408. doi: 10.1101/2023.03.06.531408. Preprint. PubMed |
| The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy. Delgado JM, Wallace Shepard L, Lamson SW, Liu SL, Shoemaker CJ. bioRxiv [Preprint]. 2023 Mar 24:2023.03.22.533681. doi: 10.1101/2023.03.22.533681. PubMed |
| An impaired ubiquitin-proteasome system increases APOBEC3A abundance. Coxon M, Dennis MA, Dananberg A, Collins CD, Wilson HE, Meekma J, Savenkova MI, Ng D, Osbron CA, Mertz TM, Goodman AG, Duttke SH, Maciejowski J, Roberts SA. NAR Cancer. 2023 Dec 19;5(4):zcad058. doi: 10.1093/narcan/zcad058. eCollection 2023 Dec. PubMed |
| The ER membrane protein complex restricts mitophagy by controlling BNIP3 turnover. Delgado JM, Shepard LW, Lamson SW, Liu SL, Shoemaker CJ. EMBO J. 2024 Jan;43(1):32-60. doi: 10.1038/s44318-023-00006-z. Epub 2023 Dec 15. PubMed |
| DOT1L stimulates MYC/Mondo transcription factor activity by promoting its degradation cycle on chromatin. Sepulveda GP, Gushchanskaia ES, Mora-Martin A, Esse R, Nikorich I, Ceballos A, Kwan J, Blum BC, Dholiya P, Emili A, Perissi V, Cardamone MD, Grishok A. bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.579191. doi: 10.1101/2024.02.06.579191. PubMed |
| Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr*VprBP*Plk4 complex in CD4(+) T cells. Park JE, Kim TS, Zeng Y, Mikolaj M, Il Ahn J, Alam MS, Monnie CM, Shi V, Zhou M, Chun TW, Maldarelli F, Narayan K, Ahn J, Ashwell JD, Strebel K, Lee KS. Nat Commun. 2024 Mar 5;15(1):2017. doi: 10.1038/s41467-024-46306-8. PubMed |
| PRMT1 promotes pancreatic cancer development and resistance to chemotherapy. Ku B, Eisenbarth D, Baek S, Jeong TK, Kang JG, Hwang D, Noh MG, Choi C, Choi S, Seol T, Kim H, Kim YH, Woo SM, Kong SY, Lim DS. Cell Rep Med. 2024 Mar 19;5(3):101461. doi: 10.1016/j.xcrm.2024.101461. Epub 2024 Mar 8. PubMed |
| Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells. Cottrell KA, Ryu S, Pierce JR, Soto Torres L, Bohlin HE, Schab AM, Weber JD. Cancer Res Commun. 2024 Apr 4;4(4):986-1003. doi: 10.1158/2767-9764.CRC-23-0488. PubMed |
| The Scribble/SGEF/Dlg1 complex regulates the stability of apical junctions in epithelial cells. Rabino A, Awadia S, Ali N, Edson A, Garcia-Mata R. bioRxiv [Preprint]. 2024 Mar 27:2024.03.26.586884. doi: 10.1101/2024.03.26.586884. PubMed |
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