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pDONR223-MAPK14 Citations (3)

Originally described in: COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
PubMed Journal

Articles Citing pDONR223-MAPK14

Articles
Engineering a Protein Binder Specific for p38alpha with Interface Expansion. Hussain M, Angus SP, Kuhlman B. Biochemistry. 2018 Jul 31;57(30):4526-4535. doi: 10.1021/acs.biochem.8b00408. Epub 2018 Jul 19. PubMed
An open library of human kinase domain constructs for automated bacterial expression. Albanese SK, Parton DL, Isik M, Rodriguez-Laureano L, Hanson SM, Behr JM, Gradia S, Jeans C, Levinson NM, Seeliger MA, Chodera JD. Biochemistry. 2018 Jul 13. doi: 10.1021/acs.biochem.7b01081. PubMed

Associated Plasmids

NRAS(Q61K) melanoma tumor formation is reduced by p38-MAPK14 activation in zebrafish models and NRAS-mutated human melanoma cells. Banik I, Cheng PF, Dooley CM, Travnickova J, Merteroglu M, Dummer R, Patton EE, Busch-Nentwich EM, Levesque MP. Pigment Cell Melanoma Res. 2021 Mar;34(2):150-162. doi: 10.1111/pcmr.12925. Epub 2020 Sep 24. PubMed

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