Mfn1-Myc Citations (19)
Originally described in: Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC J Cell Biol. 2003 Jan 20. 160(2):189-200. PubMed Journal
Articles Citing Mfn1-Myc
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| Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. Glauser L, Sonnay S, Stafa K, Moore DJ. J Neurochem. 2011 Aug;118(4):636-45. doi: 10.1111/j.1471-4159.2011.07318.x. Epub 2011 Jun 6. PubMed |
| Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily. Stafa K, Tsika E, Moser R, Musso A, Glauser L, Jones A, Biskup S, Xiong Y, Bandopadhyay R, Dawson VL, Dawson TM, Moore DJ. Hum Mol Genet. 2014 Apr 15;23(8):2055-77. doi: 10.1093/hmg/ddt600. Epub 2013 Nov 26. PubMed |
| p38 MAP kinase-dependent phosphorylation of the Gp78 E3 ubiquitin ligase controls ER-mitochondria association and mitochondria motility. Li L, Gao G, Shankar J, Joshi B, Foster LJ, Nabi IR. Mol Biol Cell. 2015 Nov 1;26(21):3828-40. doi: 10.1091/mbc.E15-02-0120. Epub 2015 Sep 2. PubMed |
| DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites. Norkett R, Modi S, Birsa N, Atkin TA, Ivankovic D, Pathania M, Trossbach SV, Korth C, Hirst WD, Kittler JT. J Biol Chem. 2016 Jan 8;291(2):613-29. doi: 10.1074/jbc.M115.699447. Epub 2015 Nov 9. PubMed |
| Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids. Pernas L, Bean C, Boothroyd JC, Scorrano L. Cell Metab. 2018 Apr 3;27(4):886-897.e4. doi: 10.1016/j.cmet.2018.02.018. PubMed |
| Epithelial-Mesenchymal Transition Directs Stem Cell Polarity via Regulation of Mitofusin. Wu MJ, Chen YS, Kim MR, Chang CC, Gampala S, Zhang Y, Wang Y, Chang CY, Yang JY, Chang CJ. Cell Metab. 2019 Apr 2;29(4):993-1002.e6. doi: 10.1016/j.cmet.2018.11.004. Epub 2018 Dec 6. PubMed |
Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.
Shen M, Wang F, Li M, Sah N, Stockton ME, Tidei JJ, Gao Y, Korabelnikov T, Kannan S, Vevea JD, Chapman ER, Bhattacharyya A, van Praag H, Zhao X.
Nat Neurosci. 2019 Mar;22(3):386-400. doi: 10.1038/s41593-019-0338-y. Epub 2019 Feb 11.
PubMed
Associated Plasmids |
| Morphological control of mitochondria as the novel mechanism of Gastrodia elata in attenuating mutant huntingtin-induced protein aggregations. Huang NK, Lin CC, Lin YL, Huang CL, Chiou CT, Lee YC, Lee SY, Huang HT, Yang YC. Phytomedicine. 2019 Jun;59:152756. doi: 10.1016/j.phymed.2018.11.016. Epub 2018 Nov 14. PubMed |
| Lysosomal Regulation of Inter-mitochondrial Contact Fate and Motility in Charcot-Marie-Tooth Type 2. Wong YC, Peng W, Krainc D. Dev Cell. 2019 Aug 5;50(3):339-354.e4. doi: 10.1016/j.devcel.2019.05.033. Epub 2019 Jun 20. PubMed |
| MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes. Freyre CAC, Rauher PC, Ejsing CS, Klemm RW. Mol Cell. 2019 Dec 5;76(5):811-825.e14. doi: 10.1016/j.molcel.2019.09.011. Epub 2019 Oct 15. PubMed |
| Dynamic organelle distribution initiates actin-based spindle migration in mouse oocytes. Duan X, Li Y, Yi K, Guo F, Wang H, Wu PH, Yang J, Mair DB, Morales EA, Kalab P, Wirtz D, Sun SX, Li R. Nat Commun. 2020 Jan 14;11(1):277. doi: 10.1038/s41467-019-14068-3. PubMed |
| The tethering function of mitofusin2 controls osteoclast differentiation by modulating the Ca(2+)-NFATc1 axis. Ballard A, Zeng R, Zarei A, Shao C, Cox L, Yan H, Franco A, Dorn GW 2nd, Faccio R, Veis DJ. J Biol Chem. 2020 May 8;295(19):6629-6640. doi: 10.1074/jbc.RA119.012023. Epub 2020 Mar 12. PubMed |
| Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological alpha-synuclein. Chung E, Choi Y, Park J, Nah W, Park J, Jung Y, Lee J, Lee H, Park S, Hwang S, Kim S, Lee J, Min D, Jo J, Kang S, Jung M, Lee PH, Ruley HE, Jo D. Sci Adv. 2020 Apr 29;6(18):eaba1193. doi: 10.1126/sciadv.aba1193. eCollection 2020 May. PubMed |
| Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction. Motori E, Atanassov I, Kochan SMV, Folz-Donahue K, Sakthivelu V, Giavalisco P, Toni N, Puyal J, Larsson NG. Sci Adv. 2020 Aug 28;6(35):eaba8271. doi: 10.1126/sciadv.aba8271. eCollection 2020 Aug. PubMed |
| Mitofusin 2 but not mitofusin 1 mediates Bcl-XL-induced mitochondrial aggregation. Du M, Yu S, Su W, Zhao M, Yang F, Liu Y, Mai Z, Wang Y, Wang X, Chen T. J Cell Sci. 2020 Oct 26;133(20):jcs245001. doi: 10.1242/jcs.245001. PubMed |
| Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development. Casellas-Diaz S, Larramona-Arcas R, Rique-Pujol G, Tena-Morraja P, Muller-Sanchez C, Segarra-Mondejar M, Gavalda-Navarro A, Villarroya F, Reina M, Martinez-Estrada OM, Soriano FX. EMBO Rep. 2021 Sep 6;22(9):e51954. doi: 10.15252/embr.202051954. Epub 2021 Jul 23. PubMed |
| Mitochondria- and ER-associated actin are required for mitochondrial fusion. Gatti P, Schiavon C, Manor U, Germain M. bioRxiv. 2023 Jun 13:2023.06.13.544768. doi: 10.1101/2023.06.13.544768. Preprint. PubMed |
| Atypical peripheral actin band formation via overactivation of RhoA and nonmuscle myosin II in mitofusin 2-deficient cells. Wang Y, Troughton LD, Xu F, Chatterjee A, Ding C, Zhao H, Cifuentes LP, Wagner RB, Wang T, Tan S, Chen J, Li L, Umulis D, Kuang S, Suter DM, Yuan C, Chan D, Huang F, Oakes PW, Deng Q. Elife. 2023 Sep 19;12:e88828. doi: 10.7554/eLife.88828. PubMed |
| Targeting mitochondrial dynamics of morphine-responsive dopaminergic neurons ameliorates opiate withdrawal. Jiang C, Huang H, Yang X, Le Q, Liu X, Ma L, Wang F. J Clin Invest. 2024 Jan 18;134(5):e171995. doi: 10.1172/JCI171995. PubMed |
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