Ai9 Citations (38)
Originally described in: A robust and high-throughput Cre reporting and characterization system for the whole mouse brain.Madisen L, Zwingman TA, Sunkin SM, Oh SW, Zariwala HA, Gu H, Ng LL, Palmiter RD, Hawrylycz MJ, Jones AR, Lein ES, Zeng H Nat Neurosci. 2010 Jan . 13(1):133-40. PubMed Journal
Articles Citing Ai9
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| A robust strategy for negative selection of Cre-loxP recombination-based excision of transgenes in induced pluripotent stem cells. Chakraborty S, Christoforou N, Fattahi A, Herzog RW, Leong KW. PLoS One. 2013 May 22;8(5):e64342. doi: 10.1371/journal.pone.0064342. Print 2013. PubMed |
Single-Step Generation of Conditional Knockout Mouse Embryonic Stem Cells.
Flemr M, Buhler M.
Cell Rep. 2015 Jul 28;12(4):709-16. doi: 10.1016/j.celrep.2015.06.051. Epub 2015 Jul 16.
PubMed
Associated Plasmids |
| Generation of Highly Enriched V2a Interneurons from Mouse Embryonic Stem Cells. Iyer NR, Huettner JE, Butts JC, Brown CR, Sakiyama-Elbert SE. Exp Neurol. 2016 Jan 16. pii: S0014-4886(16)30009-7. doi: 10.1016/j.expneurol.2016.01.011. PubMed |
| Cre dependent DREADD (designer receptors exclusively activated by designer drugs) mice. Zhu H, Aryal DK, Olsen RH, Urban DJ, Swearingen A, Forbes S, Roth BL, Hochgeschwender U. Genesis. 2016 May 19. doi: 10.1002/dvg.22949. PubMed |
| Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units. Uzel SG, Platt RJ, Subramanian V, Pearl TM, Rowlands CJ, Chan V, Boyer LA, So PT, Kamm RD. Sci Adv. 2016 Aug 3;2(8):e1501429. doi: 10.1126/sciadv.1501429. eCollection 2016 Aug. PubMed |
| A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons. Nouri N, Awatramani R. Development. 2017 Mar 1;144(5):916-927. doi: 10.1242/dev.144949. Epub 2017 Feb 7. PubMed |
| A modular approach to the design, fabrication, and characterization of muscle-powered biological machines. Raman R, Cvetkovic C, Bashir R. Nat Protoc. 2017 Mar;12(3):519-533. doi: 10.1038/nprot.2016.185. Epub 2017 Feb 9. PubMed |
| Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform. Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. Hepatology. 2017 Nov 1. doi: 10.1002/hep.29626. PubMed |
| Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair. Roostalu U, Aldeiri B, Albertini A, Humphreys N, Simonsen-Jackson M, Wong JKF, Cossu G. Circ Res. 2018 Jan 19;122(2):267-281. doi: 10.1161/CIRCRESAHA.117.312111. Epub 2017 Nov 22. PubMed |
| Characterization of knockin mice at the Rosa26, Tac1 and Plekhg1 loci generated by homologous recombination in oocytes. Wu Y, Luna MJ, Bonilla LS, Ryba NJP, Pickel JM. PLoS One. 2018 Feb 27;13(2):e0193129. doi: 10.1371/journal.pone.0193129. eCollection 2018. PubMed |
| Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations. Tasaka GI, Guenthner CJ, Shalev A, Gilday O, Luo L, Mizrahi A. Nat Commun. 2018 Feb 28;9(1):871. doi: 10.1038/s41467-018-03183-2. PubMed |
| Bioluminescence-driven optogenetic activation of transplanted neural precursor cells improves motor deficits in a Parkinson's disease mouse model. Zenchak JR, Palmateer B, Dorka N, Brown TM, Wagner LM, Medendorp WE, Petersen ED, Prakash M, Hochgeschwender U. J Neurosci Res. 2018 Mar 25. doi: 10.1002/jnr.24237. PubMed |
| Genetically engineered human cortical spheroid models of tuberous sclerosis. Blair JD, Hockemeyer D, Bateup HS. Nat Med. 2018 Oct;24(10):1568-1578. doi: 10.1038/s41591-018-0139-y. Epub 2018 Aug 20. PubMed |
| High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node. Simmons S, Sasaki N, Umemoto E, Uchida Y, Fukuhara S, Kitazawa Y, Okudaira M, Inoue A, Tohya K, Aoi K, Aoki J, Mochizuki N, Matsuno K, Takeda K, Miyasaka M, Ishii M. Elife. 2019 Oct 1;8. pii: 41239. doi: 10.7554/eLife.41239. PubMed |
| Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei. Ren J, Isakova A, Friedmann D, Zeng J, Grutzner SM, Pun A, Zhao GQ, Kolluru SS, Wang R, Lin R, Li P, Li A, Raymond JL, Luo Q, Luo M, Quake SR, Luo L. Elife. 2019 Oct 24;8. pii: 49424. doi: 10.7554/eLife.49424. PubMed |
| An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles. Evans BC, Fletcher RB, Kilchrist KV, Dailing EA, Mukalel AJ, Colazo JM, Oliver M, Cheung-Flynn J, Brophy CM, Tierney JW, Isenberg JS, Hankenson KD, Ghimire K, Lander C, Gersbach CA, Duvall CL. Nat Commun. 2019 Nov 1;10(1):5012. doi: 10.1038/s41467-019-12906-y. PubMed |
| Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations. Xu ZX, Kim GH, Tan JW, Riso AE, Sun Y, Xu EY, Liao GY, Xu H, Lee SH, Do NY, Lee CH, Clipperton-Allen AE, Kwon S, Page DT, Lee KJ, Xu B. Nat Commun. 2020 Apr 14;11(1):1797. doi: 10.1038/s41467-020-15530-3. PubMed |
| Cre-mediated, loxP independent sequential recombination of a tripartite transcriptional stop cassette allows for partial read-through transcription. Bapst AM, Dahl SL, Knopfel T, Wenger RH. Biochim Biophys Acta Gene Regul Mech. 2020 Aug;1863(8):194568. doi: 10.1016/j.bbagrm.2020.194568. Epub 2020 Apr 25. PubMed |
| An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques. Gong X, Mendoza-Halliday D, Ting JT, Kaiser T, Sun X, Bastos AM, Wimmer RD, Guo B, Chen Q, Zhou Y, Pruner M, Wu CW, Park D, Deisseroth K, Barak B, Boyden ES, Miller EK, Halassa MM, Fu Z, Bi G, Desimone R, Feng G. Neuron. 2020 Apr 14. pii: S0896-6273(20)30239-7. doi: 10.1016/j.neuron.2020.03.032. PubMed |
| CRISPR/dCas9-based Scn1a gene activation in inhibitory neurons ameliorates epileptic and behavioral phenotypes of Dravet syndrome model mice. Yamagata T, Raveau M, Kobayashi K, Miyamoto H, Tatsukawa T, Ogiwara I, Itohara S, Hensch TK, Yamakawa K. Neurobiol Dis. 2020 Jul;141:104954. doi: 10.1016/j.nbd.2020.104954. Epub 2020 May 21. PubMed |
| Standardized Reporter Systems for Purification and Imaging of Human Pluripotent Stem Cell-derived Motor Neurons and Other Cholinergic Cells. Garcia-Diaz A, Efe G, Kabra K, Patel A, Lowry ER, Shneider NA, Corneo B, Wichterle H. Neuroscience. 2020 Jun 30. pii: S0306-4522(20)30404-8. doi: 10.1016/j.neuroscience.2020.06.028. PubMed |
| ABHD11 Is Critical for Embryonic Stem Cell Expansion, Differentiation and Lipid Metabolic Homeostasis. Liu G, Ruan Y, Zhang J, Wang X, Wu W, He P, Wang J, Xiong J, Cheng Y, Liu L, Yang Y, Tian Y, Jian R. Front Cell Dev Biol. 2020 Jul 7;8:570. doi: 10.3389/fcell.2020.00570. eCollection 2020. PubMed |
| Selective postnatal excitation of neocortical pyramidal neurons results in distinctive behavioral and circuit deficits in adulthood. Medendorp WE, Bjorefeldt A, Crespo EL, Prakash M, Pal A, Waddell ML, Moore CI, Hochgeschwender U. iScience. 2021 Feb 7;24(3):102157. doi: 10.1016/j.isci.2021.102157. eCollection 2021 Mar 19. PubMed |
| Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain. Sakers K, Liu Y, Llaci L, Lee SM, Vasek MJ, Rieger MA, Brophy S, Tycksen E, Lewis R, Maloney SE, Dougherty JD. Nat Commun. 2021 Mar 9;12(1):1537. doi: 10.1038/s41467-021-21703-5. PubMed |
| Prenatal overexpression of platelet-derived growth factor receptor A results in central nervous system hypomyelination. Cardona HJ, Somasundaram A, Crabtree DM, Gadd SL, Becher OJ. Brain Behav. 2021 Oct;11(10):e2332. doi: 10.1002/brb3.2332. Epub 2021 Sep 4. PubMed |
Revisiting astrocyte to neuron conversion with lineage tracing in vivo.
Wang LL, Serrano C, Zhong X, Ma S, Zou Y, Zhang CL.
Cell. 2021 Oct 14;184(21):5465-5481.e16. doi: 10.1016/j.cell.2021.09.005. Epub 2021 Sep 27.
PubMed
Associated Plasmids |
| p21 produces a bioactive secretome that places stressed cells under immunosurveillance. Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM. Science. 2021 Oct 29;374(6567):eabb3420. doi: 10.1126/science.abb3420. Epub 2021 Oct 29. PubMed |
| Sexually Dimorphic Increases in Bone Mass Following Tissue-specific Overexpression of Runx1 in Osteoclast Precursors. Diaz-Hernandez ME, Kinter CW, Watson SR, Mella-Velazquez G, Kaiser J, Liu G, Khan NM, Roberts JL, Lorenzo J, Drissi H. Endocrinology. 2022 Sep 1;163(9):bqac113. doi: 10.1210/endocr/bqac113. PubMed |
| ER stress transforms random olfactory receptor choice into axon targeting precision. Shayya HJ, Kahiapo JK, Duffie R, Lehmann KS, Bashkirova L, Monahan K, Dalton RP, Gao J, Jiao S, Schieren I, Belluscio L, Lomvardas S. Cell. 2022 Oct 13;185(21):3896-3912.e22. doi: 10.1016/j.cell.2022.08.025. Epub 2022 Sep 26. PubMed |
| Generation of genetically engineered mice for lung cancer with mutant EGFR. Kim DS, Ji W, Kim DH, Choi YJ, Im K, Lee CW, Cho J, Min J, Woo DC, Choi CM, Lee JC, Sung YH, Rho JK. Biochem Biophys Res Commun. 2022 Dec 3;632:85-91. doi: 10.1016/j.bbrc.2022.09.104. Epub 2022 Sep 30. PubMed |
| Universal recording of cell-cell contacts in vivo for interaction-based transcriptomics. Nakandakari-Higa S, Canesso MCC, Walker S, Chudnovskiy A, Jacobsen JT, Bilanovic J, Parigi SM, Fiedorczuk K, Fuchs E, Bilate AM, Pasqual G, Mucida D, Pritykin Y, Victora GD. bioRxiv [Preprint]. 2023 Apr 18:2023.03.16.533003. doi: 10.1101/2023.03.16.533003. PubMed |
| Nerve pathology is prevented by linker proteins in mouse models for LAMA2-related muscular dystrophy. Reinhard JR, Porrello E, Lin S, Pelczar P, Previtali SC, Ruegg MA. PNAS Nexus. 2023 Mar 15;2(4):pgad083. doi: 10.1093/pnasnexus/pgad083. eCollection 2023 Apr. PubMed |
| Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex. Munz M, Bharioke A, Kosche G, Moreno-Juan V, Brignall A, Rodrigues TM, Graff-Meyer A, Ulmer T, Haeuselmann S, Pavlinic D, Ledergerber N, Gross-Scherf B, Rozsa B, Krol J, Picelli S, Cowan CS, Roska B. Cell. 2023 Apr 27;186(9):1930-1949.e31. doi: 10.1016/j.cell.2023.03.025. Epub 2023 Apr 17. PubMed |
| An inducible tricolor reporter mouse for simultaneous imaging of lysosomes, mitochondria and microtubules. Hutchison V, Lynch A, Gutierrez Gamez AM, Chen J. bioRxiv. 2023 May 22:2023.05.22.541817. doi: 10.1101/2023.05.22.541817. Preprint. PubMed |
| Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9. Thurkauf M, Lin S, Oliveri F, Grimm D, Platt RJ, Ruegg MA. Nat Commun. 2023 Sep 30;14(1):6116. doi: 10.1038/s41467-023-41769-7. PubMed |
| Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis. Takeda N, Tsuchiya A, Mito M, Natsui K, Natusi Y, Koseki Y, Tomiyoshi K, Yamazaki F, Yoshida Y, Abe H, Sano M, Kido T, Yoshioka Y, Kikuta J, Itoh T, Nishimura K, Ishii M, Ochiya T, Miyajima A, Terai S. Inflamm Regen. 2023 Oct 9;43(1):48. doi: 10.1186/s41232-023-00299-x. PubMed |
| Secreted Particle Information Transfer (SPIT) - A Cellular Platform for In Vivo Genetic Engineering. Charlesworth CT, Homma S, Suchy F, Wang S, Bhadhury J, Amaya AK, Camarena J, Zhang J, Tan TK, Igarishi K, Nakauchi H. bioRxiv [Preprint]. 2024 Jan 12:2024.01.11.575257. doi: 10.1101/2024.01.11.575257. PubMed |
| Multifaceted roles of Meg3 in cellular senescence and atherosclerosis. Cheng X, Shihabudeen Haider Ali MS, Baki VB, Moran M, Su H, Sun X. Atherosclerosis. 2024 May;392:117506. doi: 10.1016/j.atherosclerosis.2024.117506. Epub 2024 Mar 8. PubMed |
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