MSCV CreERT2 puro Citations (28)

Originally described in: Dicer1 functions as a haploinsufficient tumor suppressor.
Kumar MS, Pester RE, Chen CY, Lane K, Chin C, Lu J, Kirsch DG, Golub TR, Jacks T Genes Dev. 2009 Nov 10. ():. PubMed Journal

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Articles Citing MSCV CreERT2 puro

Articles
Pak2 kinase restrains mast cell FcepsilonRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity. Kosoff R, Chow HY, Radu M, Chernoff J. J Biol Chem. 2013 Jan 11;288(2):974-83. doi: 10.1074/jbc.M112.422295. Epub 2012 Nov 30. PubMed
Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas. Peters SL, Hlady RA, Opavska J, Klinkebiel D, Novakova S, Smith LM, Lewis RE, Karpf AR, Simpson MA, Wu L, Opavsky R. Mol Cell Biol. 2013 Nov;33(21):4321-33. doi: 10.1128/MCB.00776-13. Epub 2013 Sep 3. PubMed
Hyperactivation of mammalian target of rapamycin complex 1 (mTORC1) promotes breast cancer progression through enhancing glucose starvation-induced autophagy and Akt signaling. Chen Y, Wei H, Liu F, Guan JL. J Biol Chem. 2014 Jan 10;289(2):1164-73. doi: 10.1074/jbc.M113.526335. Epub 2013 Nov 25. PubMed
p62/SQSTM1 synergizes with autophagy for tumor growth in vivo. Wei H, Wang C, Croce CM, Guan JL. Genes Dev. 2014 Jun 1;28(11):1204-16. doi: 10.1101/gad.237354.113. PubMed
Excessive hyaluronan production promotes acquisition of cancer stem cell signatures through the coordinated regulation of Twist and the transforming growth factor beta (TGF-beta)-Snail signaling axis. Chanmee T, Ontong P, Mochizuki N, Kongtawelert P, Konno K, Itano N. J Biol Chem. 2014 Sep 19;289(38):26038-56. doi: 10.1074/jbc.M114.564120. Epub 2014 Jul 30. PubMed
Mesenchymal chemotaxis requires selective inactivation of myosin II at the leading edge via a noncanonical PLCgamma/PKCalpha pathway. Asokan SB, Johnson HE, Rahman A, King SJ, Rotty JD, Lebedeva IP, Haugh JM, Bear JE. Dev Cell. 2014 Dec 22;31(6):747-60. doi: 10.1016/j.devcel.2014.10.024. Epub 2014 Dec 4. PubMed
Loss of maintenance DNA methylation results in abnormal DNA origin firing during DNA replication. Haruta M, Shimada M, Nishiyama A, Johmura Y, Le Tallec B, Debatisse M, Nakanishi M. Biochem Biophys Res Commun. 2016 Jan 22;469(4):960-6. doi: 10.1016/j.bbrc.2015.12.090. Epub 2015 Dec 22. PubMed
Class I PI-3-Kinase Signaling Is Critical for Bone Formation through Regulation of SMAD1 Activity in Osteoblasts. Gamez B, Rodriguez-Carballo E, Graupera M, Rosa JL, Ventura F. J Bone Miner Res. 2016 Feb 20. doi: 10.1002/jbmr.2819. PubMed
ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. de Jong PR, Taniguchi K, Harris AR, Bertin S, Takahashi N, Duong J, Campos AD, Powis G, Corr M, Karin M, Raz E. Nat Commun. 2016 May 17;7:11551. doi: 10.1038/ncomms11551. PubMed
The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity. Roulland Y, Ouararhni K, Naidenov M, Ramos L, Shuaib M, Syed SH, Lone IN, Boopathi R, Fontaine E, Papai G, Tachiwana H, Gautier T, Skoufias D, Padmanabhan K, Bednar J, Kurumizaka H, Schultz P, Angelov D, Hamiche A, Dimitrov S. Mol Cell. 2016 Aug 18;63(4):674-685. doi: 10.1016/j.molcel.2016.06.023. Epub 2016 Aug 4. PubMed
The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue. Wada S, Neinast M, Jang C, Ibrahim YH, Lee G, Babu A, Li J, Hoshino A, Rowe GC, Rhee J, Martina JA, Puertollano R, Blenis J, Morley M, Baur JA, Seale P, Arany Z. Genes Dev. 2016 Nov 15;30(22):2551-2564. Epub 2016 Dec 2. PubMed
Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, Guan JL, Mulloy JC, Kumar A, Zheng Y. Autophagy. 2017 May 4;13(5):955-966. doi: 10.1080/15548627.2017.1287652. Epub 2017 Feb 15. PubMed
Targeted deletion of Crif1 in mouse epidermis impairs skin homeostasis and hair morphogenesis. Shin JM, Choi DK, Sohn KC, Kim JY, Im M, Lee Y, Seo YJ, Shong M, Lee JH, Kim CD. Sci Rep. 2017 Mar 20;7:44828. doi: 10.1038/srep44828. PubMed
CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance. Feng X, Hsu SJ, Kasbek C, Chaiken M, Price CM. Nucleic Acids Res. 2017 May 5;45(8):4281-4293. doi: 10.1093/nar/gkx125. PubMed
Prmt1-mediated translation regulation is a crucial vulnerability of cancer. Hsu JH, Hubbell-Engler B, Adelmant G, Huang J, Joyce CE, Vazquez F, Weir BA, Montgomery P, Tsherniak A, Giacomelli AO, Perry JA, Trowbridge J, Fujiwara Y, Cowley GS, Xie H, Kim W, Novina CD, Hahn WC, Marto JA, Orkin SH. Cancer Res. 2017 Jun 27. pii: canres.0216.2017. doi: 10.1158/0008-5472.CAN-17-0216. PubMed
Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response. Fok KL, Bose R, Sheng K, Chang CW, Katz-Egorov M, Culty M, Su S, Yang M, Ruan YC, Chan HC, Iavarone A, Lasorella A, Cencic R, Pelletier J, Nagano M, Xu W, Wing SS. Endocrinology. 2017 Nov 1;158(11):4000-4016. doi: 10.1210/en.2017-00396. PubMed
Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene. Sandlesh P, Juang T, Safina A, Higgins MJ, Gurova KV. PLoS One. 2018 Jun 28;13(6):e0199785. doi: 10.1371/journal.pone.0199785. eCollection 2018. PubMed
CTC1-STN1 terminates telomerase while STN1-TEN1 enables C-strand synthesis during telomere replication in colon cancer cells. Feng X, Hsu SJ, Bhattacharjee A, Wang Y, Diao J, Price CM. Nat Commun. 2018 Jul 19;9(1):2827. doi: 10.1038/s41467-018-05154-z. PubMed
A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis. Volk A, Liang K, Suraneni P, Li X, Zhao J, Bulic M, Marshall S, Pulakanti K, Malinge S, Taub J, Ge Y, Rao S, Bartom E, Shilatifard A, Crispino JD. Cancer Cell. 2018 Nov 12;34(5):707-723.e7. doi: 10.1016/j.ccell.2018.10.004. PubMed
The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells. Adane B, Ye H, Khan N, Pei S, Minhajuddin M, Stevens BM, Jones CL, D'Alessandro A, Reisz JA, Zaberezhnyy V, Gasparetto M, Ho TC, Kelly KK, Myers JR, Ashton JM, Siegenthaler J, Kume T, Campbell EL, Pollyea DA, Becker MW, Jordan CT. Cell Rep. 2019 Apr 2;27(1):238-254.e6. doi: 10.1016/j.celrep.2019.03.009. PubMed
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism. Pearson S, Loft A, Rajbhandari P, Simcox J, Lee S, Tontonoz P, Mandrup S, Villanueva CJ. Genes Dev. 2019 Jul 1;33(13-14):747-762. doi: 10.1101/gad.321059.118. Epub 2019 May 23. PubMed
Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas. Xie S, Ni J, McFaline-Figueroa JR, Wang Y, Bronson RT, Ligon KL, Wen PY, Roberts TM, Zhao JJ. Cell Rep. 2020 Sep 29;32(13):108196. doi: 10.1016/j.celrep.2020.108196. PubMed
MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARgamma-Dependent Gene Expression. Dean JM, He A, Tan M, Wang J, Lu D, Razani B, Lodhi IJ. Cell Rep. 2020 Oct 6;33(1):108228. doi: 10.1016/j.celrep.2020.108228. PubMed
HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers. Di Giorgio E, Paluvai H, Dalla E, Ranzino L, Renzini A, Moresi V, Minisini M, Picco R, Brancolini C. Genome Biol. 2021 May 10;22(1):129. doi: 10.1186/s13059-021-02340-z. PubMed
Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma. Zrimsek M, Kucharikova H, Draganic K, Dobrovolna P, Heiss Spornberger V, Winkelmayer L, Hassler MR, Lochmanova G, Zdrahal Z, Egger G. Cells. 2022 Aug 2;11(15):2380. doi: 10.3390/cells11152380. PubMed
ISG15 conjugation to proteins on nascent DNA mitigates DNA replication stress. Wardlaw CP, Petrini JHJ. Nat Commun. 2022 Oct 10;13(1):5971. doi: 10.1038/s41467-022-33535-y. PubMed
Monoacylglycerol O-acyltransferase 1 lowers adipocyte differentiation capacity in vitro but does not affect adiposity in mice. Singer JM, Shew TM, Ferguson D, Renkemeyer MK, Pietka TA, Hall AM, Finck BN, Lutkewitte AJ. Obesity (Silver Spring). 2022 Nov;30(11):2122-2133. doi: 10.1002/oby.23538. PubMed
A conditional Smg6 mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway. Katsioudi G, Dreos R, Arpa ES, Gaspari S, Liechti A, Sato M, Gabriel CH, Kramer A, Brown SA, Gatfield D. Sci Adv. 2023 Jan 13;9(2):eade2828. doi: 10.1126/sciadv.ade2828. Epub 2023 Jan 13. PubMed

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