PERK 1: PERK.WT.9E10.pCDNA Citations (13)
Originally described in: Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase.Harding HP, Zhang Y, Ron D Nature. 1999 Jan 21. 397(6716):271-4. PubMed Journal
Articles Citing PERK 1: PERK.WT.9E10.pCDNA
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Two in-and-out modulation strategies for endoplasmic reticulum stress-linked gene expression of pro-apoptotic macrophage-inhibitory cytokine 1. Park SH, Choi HJ, Yang H, Do KH, Kim J, Kim HH, Lee H, Oh CG, Lee DW, Moon Y. J Biol Chem. 2012 Jun 8;287(24):19841-55. doi: 10.1074/jbc.M111.330639. Epub 2012 Apr 17. PubMed |
PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation. Meares GP, Liu Y, Rajbhandari R, Qin H, Nozell SE, Mobley JA, Corbett JA, Benveniste EN. Mol Cell Biol. 2014 Oct;34(20):3911-25. doi: 10.1128/MCB.00980-14. Epub 2014 Aug 11. PubMed |
A functional link between the co-translational protein translocation pathway and the UPR. Plumb R, Zhang ZR, Appathurai S, Mariappan M. Elife. 2015 May 20;4. doi: 10.7554/eLife.07426. PubMed |
Effects of ER stress on unfolded protein responses, cell survival, and viral replication in primary effusion lymphoma. Shigemi Z, Baba Y, Hara N, Matsuhiro J, Kagawa H, Watanabe T, Fujimuro M. Biochem Biophys Res Commun. 2016 Jan 15;469(3):565-72. doi: 10.1016/j.bbrc.2015.12.032. Epub 2015 Dec 12. PubMed |
The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling. van Vliet AR, Giordano F, Gerlo S, Segura I, Van Eygen S, Molenberghs G, Rocha S, Houcine A, Derua R, Verfaillie T, Vangindertael J, De Keersmaecker H, Waelkens E, Tavernier J, Hofkens J, Annaert W, Carmeliet P, Samali A, Mizuno H, Agostinis P. Mol Cell. 2017 Mar 2;65(5):885-899.e6. doi: 10.1016/j.molcel.2017.01.020. Epub 2017 Feb 23. PubMed |
Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction. Chen S, Henderson A, Petriello MC, Romano KA, Gearing M, Miao J, Schell M, Sandoval-Espinola WJ, Tao J, Sha B, Graham M, Crooke R, Kleinridders A, Balskus EP, Rey FE, Morris AJ, Biddinger SB. Cell Metab. 2019 Dec 3;30(6):1141-1151.e5. doi: 10.1016/j.cmet.2019.08.021. Epub 2019 Sep 19. PubMed |
Mechanism and role of the intra-axonal Calreticulin translation in response to axonal injury. Pacheco A, Merianda TT, Twiss JL, Gallo G. Exp Neurol. 2020 Jan;323:113072. doi: 10.1016/j.expneurol.2019.113072. Epub 2019 Oct 25. PubMed |
COG5 variants lead to complex early onset retinal degeneration, upregulation of PERK and DNA damage. Tabbarah S, Tavares E, Charish J, Vincent A, Paterson A, Di Scipio M, Yin Y, Mendoza-Londono R, Maynes J, Heon E, Monnier PP. Sci Rep. 2020 Dec 4;10(1):21269. doi: 10.1038/s41598-020-77394-3. PubMed |
Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis. Read DE, Gupta A, Cawley K, Fontana L, Agostinis P, Samali A, Gupta S. Life (Basel). 2021 Jan 6;11(1). pii: life11010030. doi: 10.3390/life11010030. PubMed |
Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy. Vanhoutte D, Schips TG, Vo A, Grimes KM, Baldwin TA, Brody MJ, Accornero F, Sargent MA, Molkentin JD. Nat Commun. 2021 Jun 24;12(1):3928. doi: 10.1038/s41467-021-24215-4. PubMed |
PERK recruits E-Syt1 at ER-mitochondria contacts for mitochondrial lipid transport and respiration. Sassano ML, van Vliet AR, Vervoort E, Van Eygen S, Van den Haute C, Pavie B, Roels J, Swinnen JV, Spinazzi M, Moens L, Casteels K, Meyts I, Pinton P, Marchi S, Rochin L, Giordano F, Felipe-Abrio B, Agostinis P. J Cell Biol. 2023 Mar 6;222(3):e202206008. doi: 10.1083/jcb.202206008. Epub 2023 Feb 23. PubMed |
Ubiquitin-like protein 5 is a novel player in the UPR-PERK arm and ER stress-induced cell death. Wang W, Hawkridge AM, Ma Y, Zhang B, Mangrum JB, Hassan ZH, He T, Blat S, Guo C, Zhou H, Liu J, Wang XY, Fang X. J Biol Chem. 2023 Jul;299(7):104915. doi: 10.1016/j.jbc.2023.104915. Epub 2023 Jun 12. PubMed |
Interactome Analysis of the ER Stress Sensor Perk Uncovers Key Components of ER-Mitochondria Contact Sites and Ca(2+) Signalling. Sassano ML, Derua R, Waelkens E, Agostinis P, van Vliet AR. Contact (Thousand Oaks). 2021 Nov 29;4:25152564211052392. doi: 10.1177/25152564211052392. eCollection 2021 Jan-Dec. PubMed |
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