eIF2a 2 Citations (10)
Originally described in: eIF2-alpha constructsUnpublished
Articles Citing eIF2a 2
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Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis. Arrojo E Drigo R, Fonseca TL, Castillo M, Salathe M, Simovic G, Mohacsik P, Gereben B, Bianco AC. Mol Endocrinol. 2011 Dec;25(12):2065-75. doi: 10.1210/me.2011-1061. Epub 2011 Nov 3. PubMed |
A subunit of eukaryotic translation initiation factor 2alpha-phosphatase (CreP/PPP1R15B) regulates membrane traffic. Kloft N, Neukirch C, von Hoven G, Bobkiewicz W, Weis S, Boller K, Husmann M. J Biol Chem. 2012 Oct 12;287(42):35299-317. doi: 10.1074/jbc.M112.379883. Epub 2012 Aug 22. PubMed |
OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2. West NW, Garcia-Vargas A, Chalfant CE, Park MA. BMC Cancer. 2013 May 24;13:256. doi: 10.1186/1471-2407-13-256. PubMed |
OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation. Chen H, Song R, Wang G, Ding Z, Yang C, Zhang J, Zeng Z, Rubio V, Wang L, Zu N, Weiskoff AM, Minze LJ, Jeyabal PV, Mansour OC, Bai L, Merrick WC, Zheng S, Shi ZZ. Sci Rep. 2015 Aug 18;5:13241. doi: 10.1038/srep13241. PubMed |
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition. Zucal C, D'Agostino VG, Casini A, Mantelli B, Thongon N, Soncini D, Caffa I, Cea M, Ballestrero A, Quattrone A, Indraccolo S, Nencioni A, Provenzani A. BMC Cancer. 2015 Nov 5;15:855. doi: 10.1186/s12885-015-1845-1. PubMed |
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis. Wei Y, Meng M, Tian Z, Xie F, Yin Q, Dai C, Wang J, Zhang Q, Liu Y, Liu C, Yan F, Jiang F, Guo X. Pharmacol Res. 2019 Mar;141:114-122. doi: 10.1016/j.phrs.2018.12.017. Epub 2018 Dec 21. PubMed |
Genome-wide translational reprogramming of genes important for myocyte functions in overload-induced heart failure. Guo Q, Zhang Y, Zhang S, Jin J, Pang S, Wu X, Zhang W, Bi X, Zhang Y, Zhang Q, Jiang F. Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165649. doi: 10.1016/j.bbadis.2019.165649. Epub 2019 Dec 21. PubMed |
Activation of the eIF2alpha/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis. Bai X, Ni J, Beretov J, Wasinger VC, Wang S, Zhu Y, Graham P, Li Y. Redox Biol. 2021 Jul;43:101993. doi: 10.1016/j.redox.2021.101993. Epub 2021 Apr 28. PubMed |
Neuron-specific translational control shift ensures proteostatic resilience during ER stress. Wolzak K, Nolle A, Farina M, Abbink TE, van der Knaap MS, Verhage M, Scheper W. EMBO J. 2022 Aug 16;41(16):e110501. doi: 10.15252/embj.2021110501. Epub 2022 Jul 6. PubMed |
Protein translation rate determines neocortical neuron fate. Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosario M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC. Nat Commun. 2024 Jun 7;15(1):4879. doi: 10.1038/s41467-024-49198-w. PubMed |
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