pRK5 FLAG DEPTOR (PDZ domain) Citations (4)

Originally described in: DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival.
Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM Cell. 2009 May 13. ():. PubMed Journal

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Articles Citing pRK5 FLAG DEPTOR (PDZ domain)

Articles
p38gamma and delta promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation. Gonzalez-Teran B, Lopez JA, Rodriguez E, Leiva L, Martinez-Martinez S, Bernal JA, Jimenez-Borreguero LJ, Redondo JM, Vazquez J, Sabio G. Nat Commun. 2016 Jan 22;7:10477. doi: 10.1038/ncomms10477. PubMed
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Carbonneau M, M Gagne L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, Petrecca K, Huot ME, Mallette FA. Nat Commun. 2016 Sep 14;7:12700. doi: 10.1038/ncomms12700. PubMed
DEPTOR Prevents Osteoarthritis Development Via Interplay With TRC8 to Reduce Endoplasmic Reticulum Stress in Chondrocytes. Li K, Yang P, Zhang Y, Zhang Y, Cao H, Liu P, Huang B, Xu S, Lai P, Lei G, Liu J, Tang Y, Bai X, Zou Z. J Bone Miner Res. 2021 Feb;36(2):400-411. doi: 10.1002/jbmr.4176. Epub 2020 Sep 24. PubMed
Skeletal diseases caused by mutations in PTH1R show aberrant differentiation of skeletal progenitors due to dysregulation of DEPTOR. Csukasi F, Bosakova M, Barta T, Martin JH, Arcedo J, Barad M, Rico-Llanos GA, Zieba J, Becerra J, Krejci P, Duran I, Krakow D. Front Cell Dev Biol. 2023 Jan 16;10:963389. doi: 10.3389/fcell.2022.963389. eCollection 2022. PubMed

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