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FLAG-TRAF6-wt Citations (18)

Originally described in: Germinal center kinase is required for optimal Jun N-terminal kinase activation by Toll-like receptor agonists and is regulated by the ubiquitin proteasome system and agonist-induced, TRAF6-dependent stabilization.
Zhong J, Kyriakis JM Mol Cell Biol. 2004 Oct . 24(20):9165-75.
PubMed Journal

Articles Citing FLAG-TRAF6-wt

Articles
Leishmania donovani exploits host deubiquitinating enzyme A20, a negative regulator of TLR signaling, to subvert host immune response. Srivastav S, Kar S, Chande AG, Mukhopadhyaya R, Das PK. J Immunol. 2012 Jul 15;189(2):924-34. doi: 10.4049/jimmunol.1102845. Epub 2012 Jun 8. PubMed
IRAK-M regulates the inhibition of TLR-mediated macrophage immune response during late in vitro Leishmania donovani infection. Srivastav S, Saha A, Barua J, Ukil A, Das PK. Eur J Immunol. 2015 Oct;45(10):2787-97. doi: 10.1002/eji.201445336. Epub 2015 Jul 21. PubMed
Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. Kinsella S, Konig HG, Prehn JH. eNeuro. 2016 May 12;3(2). pii: ENEURO.0099-15.2016. doi: 10.1523/ENEURO.0099-15.2016. eCollection 2016 Mar-Apr. PubMed
ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria. Milivojevic M, Dangeard AS, Kasper CA, Tschon T, Emmenlauer M, Pique C, Schnupf P, Guignot J, Arrieumerlou C. PLoS Pathog. 2017 Feb 21;13(2):e1006224. doi: 10.1371/journal.ppat.1006224. eCollection 2017 Feb. PubMed
Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation. Min Y, Kim MJ, Lee S, Chun E, Lee KY. Autophagy. 2018;14(8):1347-1358. doi: 10.1080/15548627.2018.1474995. Epub 2018 Jul 23. PubMed
The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Arora H, Wilcox SM, Johnson LA, Munro L, Eyford BA, Pfeifer CG, Welch I, Jefferies WA. Immunity. 2019 Feb 19;50(2):418-431.e6. doi: 10.1016/j.immuni.2019.01.014. Epub 2019 Feb 12. PubMed
A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis. Sun S, Li F, Liu Y, Qu H, Wong SW, Zeng L, Yu M, Feng H, Liu H, Han D. Arch Oral Biol. 2019 May;101:100-107. doi: 10.1016/j.archoralbio.2019.03.013. Epub 2019 Mar 18. PubMed
Regulation of death receptor signaling by the autophagy protein TP53INP2. Ivanova S, Polajnar M, Narbona-Perez AJ, Hernandez-Alvarez MI, Frager P, Slobodnyuk K, Plana N, Nebreda AR, Palacin M, Gomis RR, Behrends C, Zorzano A. EMBO J. 2019 May 15;38(10). pii: embj.201899300. doi: 10.15252/embj.201899300. Epub 2019 Apr 12. PubMed
CRBN Is a Negative Regulator of Bactericidal Activity and Autophagy Activation Through Inhibiting the Ubiquitination of ECSIT and BECN1. Kim MJ, Min Y, Shim JH, Chun E, Lee KY. Front Immunol. 2019 Sep 18;10:2203. doi: 10.3389/fimmu.2019.02203. eCollection 2019. PubMed
Regulation of the autophagic PI3KC3 complex by laforin/malin E3-ubiquitin ligase, two proteins involved in Lafora disease. Sanchez-Martin P, Lahuerta M, Viana R, Knecht E, Sanz P. Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118613. doi: 10.1016/j.bbamcr.2019.118613. Epub 2019 Nov 21. PubMed
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection. Gassen NC, Niemeyer D, Muth D, Corman VM, Martinelli S, Gassen A, Hafner K, Papies J, Mosbauer K, Zellner A, Zannas AS, Herrmann A, Holsboer F, Brack-Werner R, Boshart M, Muller-Myhsok B, Drosten C, Muller MA, Rein T. Nat Commun. 2019 Dec 18;10(1):5770. doi: 10.1038/s41467-019-13659-4. PubMed
p62 is Negatively Implicated in the TRAF6-BECN1 Signaling Axis for Autophagy Activation and Cancer Progression by Toll-Like Receptor 4 (TLR4). Kim MJ, Min Y, Im JS, Son J, Lee JS, Lee KY. Cells. 2020 May 6;9(5). pii: cells9051142. doi: 10.3390/cells9051142. PubMed
HOPS/Tmub1 involvement in the NF-kB-mediated inflammatory response through the modulation of TRAF6. Bellet MM, Pieroni S, Castelli M, Piobbico D, Fallarino F, Romani L, Della-Fazia MA, Servillo G. Cell Death Dis. 2020 Oct 15;11(10):865. doi: 10.1038/s41419-020-03086-5. PubMed
AMPKalpha1 Regulates Lung and Breast Cancer Progression by Regulating TLR4-Mediated TRAF6-BECN1 Signaling Axis. Kim MJ, Min Y, Son J, Kim JY, Lee JS, Kim DH, Lee KY. Cancers (Basel). 2020 Nov 6;12(11). pii: cancers12113289. doi: 10.3390/cancers12113289. PubMed
The Interaction of TRAF6 With Neuroplastin Promotes Spinogenesis During Early Neuronal Development. Vemula SK, Malci A, Junge L, Lehmann AC, Rama R, Hradsky J, Matute RA, Weber A, Prigge M, Naumann M, Kreutz MR, Seidenbecher CI, Gundelfinger ED, Herrera-Molina R. Front Cell Dev Biol. 2020 Dec 9;8:579513. doi: 10.3389/fcell.2020.579513. eCollection 2020. PubMed
USP8 regulates liver cancer progression via the inhibition of TRAF6-mediated signal for NF-kappaB activation and autophagy induction by TLR4. Kim MJ, Choi B, Kim JY, Min Y, Kwon DH, Son J, Lee JS, Lee JS, Chun E, Lee KY. Transl Oncol. 2022 Jan;15(1):101250. doi: 10.1016/j.tranon.2021.101250. Epub 2021 Oct 20. PubMed
Hepatitis B virus X Protein Promotes Liver Cancer Progression through Autophagy Induction in Response to TLR4 Stimulation. Son J, Kim MJ, Lee JS, Kim JY, Chun E, Lee KY. Immune Netw. 2021 Oct 26;21(5):e37. doi: 10.4110/in.2021.21.e37. eCollection 2021 Oct. PubMed
USP15 negatively regulates lung cancer progression through the TRAF6-BECN1 signaling axis for autophagy induction. Kim MJ, Min Y, Jeong SK, Son J, Kim JY, Lee JS, Kim DH, Lee JS, Chun E, Lee KY. Cell Death Dis. 2022 Apr 14;13(4):348. doi: 10.1038/s41419-022-04808-7. PubMed

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