pTOPO-MCL1 Citations (15)
Originally described in: Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1.Maurer U, Charvet C, Wagman AS, Dejardin E, Green DR Mol Cell. 2006 Mar 17. 21(6):749-60. PubMed Journal
Articles Citing pTOPO-MCL1
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| GDC-0941 sensitizes breast cancer to ABT-737 in vitro and in vivo through promoting the degradation of Mcl-1. Zheng L, Yang W, Zhang C, Ding WJ, Zhu H, Lin NM, Wu HH, He QJ, Yang B. Cancer Lett. 2011 Oct 1;309(1):27-36. doi: 10.1016/j.canlet.2011.05.011. Epub 2011 Jun 12. PubMed |
| Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth. Lamers F, Schild L, den Hartog IJ, Ebus ME, Westerhout EM, Ora I, Koster J, Versteeg R, Caron HN, Molenaar JJ. Eur J Cancer. 2012 Nov;48(16):3093-103. doi: 10.1016/j.ejca.2012.01.037. Epub 2012 Feb 25. PubMed |
| Molecular interactions of prodiginines with the BH3 domain of anti-apoptotic Bcl-2 family members. Hosseini A, Espona-Fiedler M, Soto-Cerrato V, Quesada R, Perez-Tomas R, Guallar V. PLoS One. 2013;8(2):e57562. doi: 10.1371/journal.pone.0057562. Epub 2013 Feb 27. PubMed |
| Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo. Zhang C, Zhou SS, Li XR, Wang BM, Lin NM, Feng LY, Zhang DY, Zhang LH, Wang JB, Pan JP. Oncol Rep. 2013 Jun;29(6):2275-82. doi: 10.3892/or.2013.2405. Epub 2013 Apr 12. PubMed |
| Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death. Eichhorn JM, Sakurikar N, Alford SE, Chu R, Chambers TC. Cell Death Dis. 2013 Oct 3;4:e834. doi: 10.1038/cddis.2013.360. PubMed |
| Inhibition of NANOG/NANOGP8 downregulates MCL-1 in colorectal cancer cells and enhances the therapeutic efficacy of BH3 mimetics. Mattoo AR, Zhang J, Espinoza LA, Jessup JM. Clin Cancer Res. 2014 Nov 1;20(21):5446-55. doi: 10.1158/1078-0432.CCR-14-1134. Epub 2014 Sep 10. PubMed |
| MicroRNA 17-5p regulates autophagy in Mycobacterium tuberculosis-infected macrophages by targeting Mcl-1 and STAT3. Kumar R, Sahu SK, Kumar M, Jana K, Gupta P, Gupta UD, Kundu M, Basu J. Cell Microbiol. 2015 Oct 29. doi: 10.1111/cmi.12540. PubMed |
| Evodiamine induces apoptosis and enhances apoptotic effects of erlotinib in wild-type EGFR NSCLC cells via S6K1-mediated Mcl-1 inhibition. Li YL, Pan YN, Wu WJ, Mao SY, Sun J, Zhao YM, Dong JY, Zhang DY, Pan JP, Zhang C, Lin NM. Med Oncol. 2016 Feb;33(2):16. doi: 10.1007/s12032-015-0726-4. Epub 2016 Jan 13. PubMed |
| Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells. Park SH, Lee DH, Kim JL, Kim BR, Na YJ, Jo MJ, Jeong YA, Lee SY, Lee SI, Lee YY, Oh SC. Oncotarget. 2016 Sep 13;7(37):59503-59518. doi: 10.18632/oncotarget.11147. PubMed |
| Nedaplatin enhanced apoptotic effects of ABT-737 in human cancer cells via Mcl-1 inhibition. Zhang C, Li YL, Weng X, Li LY, Zhou MX, Zhang DY, Lin NM. Oncol Lett. 2016 Nov;12(5):4195-4202. Epub 2016 Sep 20. PubMed |
| Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis. Hogstrand K, Darmanin S, Forshell TP, Grandien A. Oncotarget. 2018 Apr 20;9(30):21396-21410. doi: 10.18632/oncotarget.25113. eCollection 2018 Apr 20. PubMed |
| Targeting Polo-like kinase 1 and TRAIL enhances apoptosis in non-small cell lung cancer. Noor A, Umelo IA, Kronenberger P, Giron P, De Vlieghere E, De Wever O, Teugels E, De Greve J. Oncotarget. 2018 Jun 19;9(47):28731-28744. doi: 10.18632/oncotarget.25618. eCollection 2018 Jun 19. PubMed |
| Mcl1 protein levels and Caspase-7 executioner protease control axial organizer cells survival. Sena E, Bou-Rouphael J, Rocques N, Carron-Homo C, Durand BC. Dev Dyn. 2020 Jul;249(7):847-866. doi: 10.1002/dvdy.169. Epub 2020 Mar 16. PubMed |
| Mcl-1 inhibition overcomes BET inhibitor resistance induced by low FBW7 expression in breast cancer. Wang X, Wei X, Cao Y, Xing P. J Cell Mol Med. 2022 Mar;26(5):1672-1683. doi: 10.1111/jcmm.17210. Epub 2022 Feb 7. PubMed |
| MARCH5 regulates mitotic apoptosis through MCL1-dependent and independent mechanisms. Wang Y, Poon RYC. Cell Death Differ. 2023 Mar;30(3):753-765. doi: 10.1038/s41418-022-01080-2. Epub 2022 Nov 3. PubMed |
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