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Addgene

Lenti-sgRNA-Cre-GpNLuc-sgmMRE11
(Plasmid #208384)

Ordering

This material is available to academics and nonprofits only.
Item Catalog # Description Quantity Price (USD)
Plasmid 208384 Standard format: Plasmid sent in bacteria as agar stab 1 $85

Backbone

  • Vector backbone
    LentiCRISPR V2-Cre-NLuc
  • Vector type
    Mammalian Expression, Lentiviral, Luciferase

Growth in Bacteria

  • Bacterial Resistance(s)
    Ampicillin, 100 μg/mL
  • Growth Temperature
    37°C
  • Growth Strain(s)
    NEB Stable
  • Copy number
    High Copy

Gene/Insert

  • Gene/Insert name
    sgMRE11
  • gRNA/shRNA sequence
    Unspecified
  • Species
    M. musculus (mouse)
  • Mutation
    WT
  • Entrez Gene
    Mre11a (a.k.a. Mre11, Mre11b)

Cloning Information

Resource Information

Terms and Licenses

Trademarks:
  • Zeocin® is an InvivoGen trademark.
How to cite this plasmid ( Back to top)

These plasmids were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications.

  • For your Materials & Methods section:

    Lenti-sgRNA-Cre-GpNLuc-sgmMRE11 was a gift from Gaorav Gupta (Addgene plasmid # 208384 ; http://n2t.net/addgene:208384 ; RRID:Addgene_208384)
  • For your References section:

    MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis. Cho MG, Kumar RJ, Lin CC, Boyer JA, Shahir JA, Fagan-Solis K, Simpson DA, Fan C, Foster CE, Goddard AM, Lerner LM, Ellington SW, Wang Q, Wang Y, Ho AY, Liu P, Perou CM, Zhang Q, McGinty RK, Purvis JE, Gupta GP. Nature. 2024 Jan 10. doi: 10.1038/s41586-023-06889-6. 10.1038/s41586-023-06889-6 PubMed 38200309