Skip to main content
Addgene

pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA Citations (201)

Originally described in: Cre-activated AAV expression plasmids
Unpublished

Articles Citing pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA

Articles
Optogenetic probing of fast glutamatergic transmission from hypocretin/orexin to histamine neurons in situ. Schone C, Cao ZF, Apergis-Schoute J, Adamantidis A, Sakurai T, Burdakov D. J Neurosci. 2012 Sep 5;32(36):12437-43. doi: 10.1523/JNEUROSCI.0706-12.2012. PubMed
OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons. Leao RN, Mikulovic S, Leao KE, Munguba H, Gezelius H, Enjin A, Patra K, Eriksson A, Loew LM, Tort AB, Kullander K. Nat Neurosci. 2012 Nov;15(11):1524-30. doi: 10.1038/nn.3235. Epub 2012 Oct 7. PubMed
Target-specific suppression of GABA release from parvalbumin interneurons in the basolateral amygdala by dopamine. Chu HY, Ito W, Li J, Morozov A. J Neurosci. 2012 Oct 17;32(42):14815-20. doi: 10.1523/JNEUROSCI.2997-12.2012. PubMed
Layer-specific excitatory circuits differentially control recurrent network dynamics in the neocortex. Beltramo R, D'Urso G, Dal Maschio M, Farisello P, Bovetti S, Clovis Y, Lassi G, Tucci V, De Pietri Tonelli D, Fellin T. Nat Neurosci. 2013 Feb;16(2):227-34. doi: 10.1038/nn.3306. Epub 2013 Jan 13. PubMed
Noradrenaline is a stress-associated metaplastic signal at GABA synapses. Inoue W, Baimoukhametova DV, Fuzesi T, Wamsteeker Cusulin JI, Koblinger K, Whelan PJ, Pittman QJ, Bains JS. Nat Neurosci. 2013 May;16(5):605-12. doi: 10.1038/nn.3373. Epub 2013 Apr 7. PubMed
Characterization of corticotropin-releasing hormone neurons in the paraventricular nucleus of the hypothalamus of Crh-IRES-Cre mutant mice. Wamsteeker Cusulin JI, Fuzesi T, Watts AG, Bains JS. PLoS One. 2013 May 28;8(5):e64943. doi: 10.1371/journal.pone.0064943. Print 2013. PubMed
Linear transformation of thalamocortical input by intracortical excitation. Li YT, Ibrahim LA, Liu BH, Zhang LI, Tao HW. Nat Neurosci. 2013 Sep;16(9):1324-30. doi: 10.1038/nn.3494. Epub 2013 Aug 11. PubMed
Intracortical multiplication of thalamocortical signals in mouse auditory cortex. Li LY, Li YT, Zhou M, Tao HW, Zhang LI. Nat Neurosci. 2013 Sep;16(9):1179-81. doi: 10.1038/nn.3493. Epub 2013 Aug 11. PubMed
A reorganized GABAergic circuit in a model of epilepsy: evidence from optogenetic labeling and stimulation of somatostatin interneurons. Peng Z, Zhang N, Wei W, Huang CS, Cetina Y, Otis TS, Houser CR. J Neurosci. 2013 Sep 4;33(36):14392-405. doi: 10.1523/JNEUROSCI.2045-13.2013. PubMed
Skilled reaching relies on a V2a propriospinal internal copy circuit. Azim E, Jiang J, Alstermark B, Jessell TM. Nature. 2014 Apr 17;508(7496):357-63. doi: 10.1038/nature13021. Epub 2014 Feb 2. PubMed

Associated Plasmids

Optogenetic modulation of descending prefrontocortical inputs to the dorsal raphe bidirectionally bias socioaffective choices after social defeat. Challis C, Beck SG, Berton O. Front Behav Neurosci. 2014 Feb 17;8:43. doi: 10.3389/fnbeh.2014.00043. eCollection 2014. PubMed
Scaling down of balanced excitation and inhibition by active behavioral states in auditory cortex. Zhou M, Liang F, Xiong XR, Li L, Li H, Xiao Z, Tao HW, Zhang LI. Nat Neurosci. 2014 Jun;17(6):841-50. doi: 10.1038/nn.3701. Epub 2014 Apr 20. PubMed
Presynaptic inhibition of spinal sensory feedback ensures smooth movement. Fink AJ, Croce KR, Huang ZJ, Abbott LF, Jessell TM, Azim E. Nature. 2014 May 1;509(7498):43-8. doi: 10.1038/nature13276. PubMed
Equalizing excitation-inhibition ratios across visual cortical neurons. Xue M, Atallah BV, Scanziani M. Nature. 2014 Jul 31;511(7511):596-600. doi: 10.1038/nature13321. Epub 2014 Jun 22. PubMed

Associated Plasmids

Noradrenalin and dopamine receptors both control cAMP-PKA signaling throughout the cerebral cortex. Nomura S, Bouhadana M, Morel C, Faure P, Cauli B, Lambolez B, Hepp R. Front Cell Neurosci. 2014 Aug 21;8:247. doi: 10.3389/fncel.2014.00247. eCollection 2014. PubMed
Optogenetic perturbation of preBotzinger complex inhibitory neurons modulates respiratory pattern. Sherman D, Worrell JW, Cui Y, Feldman JL. Nat Neurosci. 2015 Mar;18(3):408-14. doi: 10.1038/nn.3938. Epub 2015 Feb 2. PubMed
A subcortical inhibitory signal for behavioral arrest in the thalamus. Giber K, Diana MA, Plattner VM, Dugue GP, Bokor H, Rousseau CV, Magloczky Z, Havas L, Hangya B, Wildner H, Zeilhofer HU, Dieudonne S, Acsady L. Nat Neurosci. 2015 Apr;18(4):562-8. doi: 10.1038/nn.3951. Epub 2015 Feb 23. PubMed
Whole-brain mapping of inputs to projection neurons and cholinergic interneurons in the dorsal striatum. Guo Q, Wang D, He X, Feng Q, Lin R, Xu F, Fu L, Luo M. PLoS One. 2015 Apr 1;10(4):e0123381. doi: 10.1371/journal.pone.0123381. eCollection 2015. PubMed
Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons. Wang D, He X, Zhao Z, Feng Q, Lin R, Sun Y, Ding T, Xu F, Luo M, Zhan C. Front Neuroanat. 2015 Mar 27;9:40. doi: 10.3389/fnana.2015.00040. eCollection 2015. PubMed
Sensory Cortical Control of a Visually Induced Arrest Behavior via Corticotectal Projections. Liang F, Xiong XR, Zingg B, Ji XY, Zhang LI, Tao HW. Neuron. 2015 May 6;86(3):755-67. doi: 10.1016/j.neuron.2015.03.048. Epub 2015 Apr 23. PubMed
Nicotinic Transmission onto Layer 6 Cortical Neurons Relies on Synaptic Activation of Non-alpha7 Receptors. Hay YA, Lambolez B, Tricoire L. Cereb Cortex. 2015 May 1. pii: bhv085. PubMed
Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine. Kim IH, Rossi MA, Aryal DK, Racz B, Kim N, Uezu A, Wang F, Wetsel WC, Weinberg RJ, Yin H, Soderling SH. Nat Neurosci. 2015 Jun;18(6):883-91. doi: 10.1038/nn.4015. Epub 2015 May 4. PubMed
Layer 4 pyramidal neurons exhibit robust dendritic spine plasticity in vivo after input deprivation. Miquelajauregui A, Kribakaran S, Mostany R, Badaloni A, Consalez GG, Portera-Cailliau C. J Neurosci. 2015 May 6;35(18):7287-94. doi: 10.1523/JNEUROSCI.5215-14.2015. PubMed
A novel inhibitory nucleo-cortical circuit controls cerebellar Golgi cell activity. Ankri L, Husson Z, Pietrajtis K, Proville R, Lena C, Yarom Y, Dieudonne S, Uusisaari MY. Elife. 2015 May 12;4. doi: 10.7554/eLife.06262. PubMed
Synergy of direct and indirect cholinergic septo-hippocampal pathways coordinates firing in hippocampal networks. Dannenberg H, Pabst M, Braganza O, Schoch S, Niediek J, Bayraktar M, Mormann F, Beck H. J Neurosci. 2015 Jun 3;35(22):8394-410. doi: 10.1523/JNEUROSCI.4460-14.2015. PubMed
Auditory cortex controls sound-driven innate defense behaviour through corticofugal projections to inferior colliculus. Xiong XR, Liang F, Zingg B, Ji XY, Ibrahim LA, Tao HW, Zhang LI. Nat Commun. 2015 Jun 11;6:7224. doi: 10.1038/ncomms8224. PubMed
Wakefulness Is Governed by GABA and Histamine Cotransmission. Yu X, Ye Z, Houston CM, Zecharia AY, Ma Y, Zhang Z, Uygun DS, Parker S, Vyssotski AL, Yustos R, Franks NP, Brickley SG, Wisden W. Neuron. 2015 Jun 17. pii: S0896-6273(15)00516-4. doi: 10.1016/j.neuron.2015.06.003. PubMed

Associated Plasmids

Parvalbumin-Positive Inhibitory Interneurons Oppose Propagation But Favor Generation of Focal Epileptiform Activity. Sessolo M, Marcon I, Bovetti S, Losi G, Cammarota M, Ratto GM, Fellin T, Carmignoto G. J Neurosci. 2015 Jul 1;35(26):9544-57. doi: 10.1523/JNEUROSCI.5117-14.2015. PubMed
Optogenetics in Freely Moving Mammals: Dopamine and Reward. Zhang F, Tsai HC, Airan RD, Stuber GD, Adamantidis AR, de Lecea L, Bonci A, Deisseroth K. Cold Spring Harb Protoc. 2015 Aug 3;2015(8):715-24. doi: 10.1101/pdb.top086330. PubMed
Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. Cork SC, Richards JE, Holt MK, Gribble FM, Reimann F, Trapp S. Mol Metab. 2015 Aug 5;4(10):718-31. doi: 10.1016/j.molmet.2015.07.008. eCollection 2015 Oct. PubMed
Ectopic Expression of alpha6 and delta GABAA Receptor Subunits in Hilar Somatostatin Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus. Tong X, Peng Z, Zhang N, Cetina Y, Huang CS, Wallner M, Otis TS, Houser CR. J Neurosci. 2015 Dec 9;35(49):16142-58. doi: 10.1523/JNEUROSCI.2853-15.2015. PubMed
Selectively driving cholinergic fibers optically in the thalamic reticular nucleus promotes sleep. Ni KM, Hou XJ, Yang CH, Dong P, Li Y, Zhang Y, Jiang P, Berg DK, Duan S, Li XM. Elife. 2016 Feb 11;5. pii: e10382. doi: 10.7554/eLife.10382. PubMed
Brain-Wide Maps of Synaptic Input to Cortical Interneurons. Wall NR, De La Parra M, Sorokin JM, Taniguchi H, Huang ZJ, Callaway EM. J Neurosci. 2016 Apr 6;36(14):4000-9. doi: 10.1523/JNEUROSCI.3967-15.2016. PubMed
Activation of Pyramidal Neurons in Mouse Medial Prefrontal Cortex Enhances Food-Seeking Behavior While Reducing Impulsivity in the Absence of an Effect on Food Intake. Warthen DM, Lambeth PS, Ottolini M, Shi Y, Barker BS, Gaykema RP, Newmyer BA, Joy-Gaba J, Ohmura Y, Perez-Reyes E, Guler AD, Patel MK, Scott MM. Front Behav Neurosci. 2016 Mar 30;10:63. doi: 10.3389/fnbeh.2016.00063. eCollection 2016. PubMed
Awake dynamics and brain-wide direct inputs of hypothalamic MCH and orexin networks. Gonzalez JA, Iordanidou P, Strom M, Adamantidis A, Burdakov D. Nat Commun. 2016 Apr 22;7:11395. doi: 10.1038/ncomms11395. PubMed
Multimodal and Site-Specific Plasticity of Amygdala Parvalbumin Interneurons after Fear Learning. Lucas EK, Jegarl AM, Morishita H, Clem RL. Neuron. 2016 Aug 3;91(3):629-43. doi: 10.1016/j.neuron.2016.06.032. Epub 2016 Jul 14. PubMed
A cholinergic basal forebrain feeding circuit modulates appetite suppression. Herman AM, Ortiz-Guzman J, Kochukov M, Herman I, Quast KB, Patel JM, Tepe B, Carlson JC, Ung K, Selever J, Tong Q, Arenkiel BR. Nature. 2016 Oct 13;538(7624):253-256. doi: 10.1038/nature19789. Epub 2016 Oct 3. PubMed
Whole-Brain Monosynaptic Afferent Inputs to Basal Forebrain Cholinergic System. Hu R, Jin S, He X, Xu F, Hu J. Front Neuroanat. 2016 Oct 10;10:98. eCollection 2016. PubMed
GABAb Receptor Mediates Opposing Adaptations of GABA Release From Two Types of Prefrontal Interneurons After Observational Fear. Liu L, Ito W, Morozov A. Neuropsychopharmacology. 2017 Jan 4. doi: 10.1038/npp.2016.273. PubMed
Organization of the Claustrum-to-Entorhinal Cortical Connection in Mice. Kitanishi T, Matsuo N. J Neurosci. 2017 Jan 11;37(2):269-280. doi: 10.1523/JNEUROSCI.1360-16.2016. PubMed
Transient inhibition and long-term facilitation of locomotion by phasic optogenetic activation of serotonin neurons. Correia PA, Lottem E, Banerjee D, Machado AS, Carey MR, Mainen ZF. Elife. 2017 Feb 14;6. pii: e20975. doi: 10.7554/eLife.20975. PubMed
Near-infrared fluorescent protein iRFP713 as a reporter protein for optogenetic vectors, a transgenic Cre-reporter rat, and other neuronal studies. Richie CT, Whitaker LR, Whitaker KW, Necarsulmer J, Baldwin HA, Zhang Y, Fortuno L, Hinkle JJ, Koivula P, Henderson MJ, Sun W, Wang K, Smith JC, Pickel J, Ji N, Hope BT, Harvey BK. J Neurosci Methods. 2017 Jun 1;284:1-14. doi: 10.1016/j.jneumeth.2017.03.020. Epub 2017 Apr 2. PubMed

Associated Plasmids

A Central Catecholaminergic Circuit Controls Blood Glucose Levels during Stress. Zhao Z, Wang L, Gao W, Hu F, Zhang J, Ren Y, Lin R, Feng Q, Cheng M, Ju D, Chi Q, Wang D, Song S, Luo M, Zhan C. Neuron. 2017 Jul 5;95(1):138-152.e5. doi: 10.1016/j.neuron.2017.05.031. Epub 2017 Jun 15. PubMed
Chemical reactivation of resin-embedded pHuji adds red for simultaneous two-color imaging with EGFP. Guo W, Liu X, Liu Y, Gang Y, He X, Jia Y, Yin F, Li P, Huang F, Zhou H, Wang X, Gong H, Luo Q, Xu F, Zeng S. Biomed Opt Express. 2017 Jun 15;8(7):3281-3288. doi: 10.1364/BOE.8.003281. eCollection 2017 Jul 1. PubMed
Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb. Case DT, Burton SD, Gedeon JY, Williams SG, Urban NN, Seal RP. Nat Commun. 2017 Sep 21;8(1):652. doi: 10.1038/s41467-017-00765-4. PubMed
Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling. Resch JM, Fenselau H, Madara JC, Wu C, Campbell JN, Lyubetskaya A, Dawes BA, Tsai LT, Li MM, Livneh Y, Ke Q, Kang PM, Fejes-Toth G, Naray-Fejes-Toth A, Geerling JC, Lowell BB. Neuron. 2017 Sep 27;96(1):190-206.e7. doi: 10.1016/j.neuron.2017.09.014. PubMed
Functional comparison of corticostriatal and thalamostriatal postsynaptic responses in striatal neurons of the mouse. Arias-Garcia MA, Tapia D, Laville JA, Calderon VM, Ramiro-Cortes Y, Bargas J, Galarraga E. Brain Struct Funct. 2018 Apr;223(3):1229-1253. doi: 10.1007/s00429-017-1536-6. Epub 2017 Nov 3. PubMed
GLP-1 action in the mouse bed nucleus of the stria terminalis. Williams DL, Lilly NA, Edwards IJ, Yao P, Richards JE, Trapp S. Neuropharmacology. 2018 Mar 15;131:83-95. doi: 10.1016/j.neuropharm.2017.12.007. Epub 2017 Dec 6. PubMed
A Non-canonical Reticular-Limbic Central Auditory Pathway via Medial Septum Contributes to Fear Conditioning. Zhang GW, Sun WJ, Zingg B, Shen L, He J, Xiong Y, Tao HW, Zhang LI. Neuron. 2018 Jan 17;97(2):406-417.e4. doi: 10.1016/j.neuron.2017.12.010. Epub 2017 Dec 28. PubMed
A neural basis for antagonistic control of feeding and compulsive behaviors. Mangieri LR, Lu Y, Xu Y, Cassidy RM, Xu Y, Arenkiel BR, Tong Q. Nat Commun. 2018 Jan 4;9(1):52. doi: 10.1038/s41467-017-02534-9. PubMed
Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes. Mariotti L, Losi G, Lia A, Melone M, Chiavegato A, Gomez-Gonzalo M, Sessolo M, Bovetti S, Forli A, Zonta M, Requie LM, Marcon I, Pugliese A, Viollet C, Bettler B, Fellin T, Conti F, Carmignoto G. Nat Commun. 2018 Jan 8;9(1):82. doi: 10.1038/s41467-017-02642-6. PubMed
Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation. Gelegen C, Miracca G, Ran MZ, Harding EC, Ye Z, Yu X, Tossell K, Houston CM, Yustos R, Hawkins ED, Vyssotski AL, Dong HL, Wisden W, Franks NP. Curr Biol. 2018 Feb 19;28(4):580-587.e5. doi: 10.1016/j.cub.2017.12.050. Epub 2018 Feb 1. PubMed
Overexpression of channelrhodopsin-2 interferes with the GABAb receptor-mediated depression of GABA release from the somatostatin-containing interneurons of the prefrontal cortex. Liu L, Ito W, Morozov A. Neurophotonics. 2018 Apr;5(2):025003. doi: 10.1117/1.NPh.5.2.025003. Epub 2018 Mar 1. PubMed
Control of voluntary and optogenetically perturbed locomotion by spike rate and timing of neurons of the mouse cerebellar nuclei. Sarnaik R, Raman IM. Elife. 2018 Apr 16;7. pii: 29546. doi: 10.7554/eLife.29546. PubMed
Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake. Jeong JH, Lee DK, Liu SM, Chua SC Jr, Schwartz GJ, Jo YH. PLoS Biol. 2018 Apr 24;16(4):e2004399. doi: 10.1371/journal.pbio.2004399. eCollection 2018 Apr. PubMed
Adeno-associated Virus-mediated Transgene Expression in Genetically Defined Neurons of the Spinal Cord. Haenraets K, Albisetti GW, Foster E, Wildner H. J Vis Exp. 2018 May 12;(135). doi: 10.3791/57382. PubMed
Synaptic Mechanisms for Bandwidth Tuning in Awake Mouse Primary Auditory Cortex. Li H, Liang F, Zhong W, Yan L, Mesik L, Xiao Z, Tao HW, Zhang LI. Cereb Cortex. 2018 Jul 12. pii: 5052731. doi: 10.1093/cercor/bhy165. PubMed
Co-transmission of acetylcholine and GABA regulates hippocampal states. Takacs VT, Cserep C, Schlingloff D, Posfai B, Szonyi A, Sos KE, Kornyei Z, Denes A, Gulyas AI, Freund TF, Nyiri G. Nat Commun. 2018 Jul 20;9(1):2848. doi: 10.1038/s41467-018-05136-1. PubMed
Transforming Sensory Cues into Aversive Emotion via Septal-Habenular Pathway. Zhang GW, Shen L, Zhong W, Xiong Y, Zhang LI, Tao HW. Neuron. 2018 Sep 5;99(5):1016-1028.e5. doi: 10.1016/j.neuron.2018.07.023. Epub 2018 Aug 16. PubMed
VGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons. Wozny C, Beed P, Nitzan N, Possnecker Y, Rost BR, Schmitz D. Front Cell Neurosci. 2018 Oct 2;12:337. doi: 10.3389/fncel.2018.00337. eCollection 2018. PubMed

Associated Plasmids

Presynaptic mGluRs Control the Duration of Endocannabinoid-Mediated DSI. Colmers PLW, Bains JS. J Neurosci. 2018 Dec 5;38(49):10444-10453. doi: 10.1523/JNEUROSCI.1097-18.2018. Epub 2018 Oct 24. PubMed
Optogenetic Activation of A11 Region Increases Motor Activity. Koblinger K, Jean-Xavier C, Sharma S, Fuzesi T, Young L, Eaton SEA, Kwok CHT, Bains JS, Whelan PJ. Front Neural Circuits. 2018 Oct 11;12:86. doi: 10.3389/fncir.2018.00086. eCollection 2018. PubMed
Identifying the pathways required for coping behaviours associated with sustained pain. Huang T, Lin SH, Malewicz NM, Zhang Y, Zhang Y, Goulding M, LaMotte RH, Ma Q. Nature. 2019 Jan;565(7737):86-90. doi: 10.1038/s41586-018-0793-8. Epub 2018 Dec 10. PubMed
GABA and glutamate neurons in the VTA regulate sleep and wakefulness. Yu X, Li W, Ma Y, Tossell K, Harris JJ, Harding EC, Ba W, Miracca G, Wang D, Li L, Guo J, Chen M, Li Y, Yustos R, Vyssotski AL, Burdakov D, Yang Q, Dong H, Franks NP, Wisden W. Nat Neurosci. 2019 Jan;22(1):106-119. doi: 10.1038/s41593-018-0288-9. Epub 2018 Dec 17. PubMed

Associated Plasmids

Systemic AAV vectors for widespread and targeted gene delivery in rodents. Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Nat Protoc. 2019 Feb;14(2):379-414. doi: 10.1038/s41596-018-0097-3. PubMed

Associated Plasmids

Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson's Disease Models. Tanimura A, Du Y, Kondapalli J, Wokosin DL, Surmeier DJ. Neuron. 2019 Feb 6;101(3):444-458.e6. doi: 10.1016/j.neuron.2018.12.004. Epub 2019 Jan 15. PubMed
Limbic Neurons Shape Sex Recognition and Social Behavior in Sexually Naive Males. Bayless DW, Yang T, Mason MM, Susanto AAT, Lobdell A, Shah NM. Cell. 2019 Feb 21;176(5):1190-1205.e20. doi: 10.1016/j.cell.2018.12.041. Epub 2019 Jan 31. PubMed
A hypothalamus-habenula circuit controls aversion. Lazaridis I, Tzortzi O, Weglage M, Martin A, Xuan Y, Parent M, Johansson Y, Fuzik J, Furth D, Fenno LE, Ramakrishnan C, Silberberg G, Deisseroth K, Carlen M, Meletis K. Mol Psychiatry. 2019 Feb 12. pii: 10.1038/s41380-019-0369-5. doi: 10.1038/s41380-019-0369-5. PubMed
A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space. Trouche S, Koren V, Doig NM, Ellender TJ, El-Gaby M, Lopes-Dos-Santos V, Reeve HM, Perestenko PV, Garas FN, Magill PJ, Sharott A, Dupret D. Cell. 2019 Mar 7;176(6):1393-1406.e16. doi: 10.1016/j.cell.2018.12.037. Epub 2019 Feb 14. PubMed

Associated Plasmids

The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits. Li MM, Madara JC, Steger JS, Krashes MJ, Balthasar N, Campbell JN, Resch JM, Conley NJ, Garfield AS, Lowell BB. Neuron. 2019 May 8;102(3):653-667.e6. doi: 10.1016/j.neuron.2019.02.028. Epub 2019 Mar 14. PubMed
Routing Hippocampal Information Flow through Parvalbumin Interneuron Plasticity in Area CA2. Nasrallah K, Therreau L, Robert V, Huang AJY, McHugh TJ, Piskorowski RA, Chevaleyre V. Cell Rep. 2019 Apr 2;27(1):86-98.e3. doi: 10.1016/j.celrep.2019.03.014. PubMed
Local and Global Influences of Visual Spatial Selection and Locomotion in Mouse Primary Visual Cortex. McBride EG, Lee SJ, Callaway EM. Curr Biol. 2019 May 20;29(10):1592-1605.e5. doi: 10.1016/j.cub.2019.03.065. Epub 2019 May 2. PubMed
Whole Brain Mapping of Long-Range Direct Input to Glutamatergic and GABAergic Neurons in Motor Cortex. Luo P, Li A, Zheng Y, Han Y, Tian J, Xu Z, Gong H, Li X. Front Neuroanat. 2019 Apr 17;13:44. doi: 10.3389/fnana.2019.00044. eCollection 2019. PubMed
SatB2-Expressing Neurons in the Parabrachial Nucleus Encode Sweet Taste. Fu O, Iwai Y, Kondoh K, Misaka T, Minokoshi Y, Nakajima KI. Cell Rep. 2019 May 7;27(6):1650-1656.e4. doi: 10.1016/j.celrep.2019.04.040. PubMed
Cholinergic modulation of striatal nitric oxide-producing interneurons. Melendez-Zaidi AE, Lakshminarasimhah H, Surmeier DJ. Eur J Neurosci. 2019 Dec;50(11):3713-3731. doi: 10.1111/ejn.14528. Epub 2019 Aug 21. PubMed
Identification of a neurocircuit underlying regulation of feeding by stress-related emotional responses. Xu Y, Lu Y, Cassidy RM, Mangieri LR, Zhu C, Huang X, Jiang Z, Justice NJ, Xu Y, Arenkiel BR, Tong Q. Nat Commun. 2019 Aug 1;10(1):3446. doi: 10.1038/s41467-019-11399-z. PubMed
In Vitro Optogenetic Characterization of Neuropeptide Release from Prefrontal Cortical Somatostatin Neurons. Dao NC, Brockway DF, Crowley NA. Neuroscience. 2019 Nov 1;419:1-4. doi: 10.1016/j.neuroscience.2019.08.014. Epub 2019 Sep 2. PubMed
Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling. Chokshi V, Gao M, Grier BD, Owens A, Wang H, Worley PF, Lee HK. Neuron. 2019 Nov 20;104(4):736-748.e6. doi: 10.1016/j.neuron.2019.08.017. Epub 2019 Sep 25. PubMed
The rostroventral part of the thalamic reticular nucleus modulates fear extinction. Lee JH, Latchoumane CV, Park J, Kim J, Jeong J, Lee KH, Shin HS. Nat Commun. 2019 Oct 11;10(1):4637. doi: 10.1038/s41467-019-12496-9. PubMed
A customizable microfluidic platform for medium-throughput modeling of neuromuscular circuits. Bellmann J, Goswami RY, Girardo S, Rein N, Hosseinzadeh Z, Hicks MR, Busskamp V, Pyle AD, Werner C, Sterneckert J. Biomaterials. 2019 Dec;225:119537. doi: 10.1016/j.biomaterials.2019.119537. Epub 2019 Oct 8. PubMed
Identifying Parabrachial Neurons Selectively Regulating Satiety for Highly Palatable Food in Mice. Rodriguez E, Ryu D, Zhao S, Han BX, Wang F. eNeuro. 2019 Nov 20;6(6). pii: ENEURO.0252-19.2019. doi: 10.1523/ENEURO.0252-19.2019. Print 2019 Nov/Dec. PubMed
Interhemispherically dynamic representation of an eye movement-related activity in mouse frontal cortex. Sato TR, Itokazu T, Osaki H, Ohtake M, Yamamoto T, Sohya K, Maki T, Sato TK. Elife. 2019 Nov 5;8. pii: 50855. doi: 10.7554/eLife.50855. PubMed
Periodic Remodeling in a Neural Circuit Governs Timing of Female Sexual Behavior. Inoue S, Yang R, Tantry A, Davis CH, Yang T, Knoedler JR, Wei Y, Adams EL, Thombare S, Golf SR, Neve RL, Tessier-Lavigne M, Ding JB, Shah NM. Cell. 2019 Nov 27;179(6):1393-1408.e16. doi: 10.1016/j.cell.2019.10.025. Epub 2019 Nov 14. PubMed
GABAergic Restriction of Network Dynamics Regulates Interneuron Survival in the Developing Cortex. Duan ZRS, Che A, Chu P, Modol L, Bollmann Y, Babij R, Fetcho RN, Otsuka T, Fuccillo MV, Liston C, Pisapia DJ, Cossart R, De Marco Garcia NV. Neuron. 2020 Jan 8;105(1):75-92.e5. doi: 10.1016/j.neuron.2019.10.008. Epub 2019 Nov 25. PubMed
Activity in Lateral Visual Areas Contributes to Surround Suppression in Awake Mouse V1. Vangeneugden J, van Beest EH, Cohen MX, Lorteije JAM, Mukherjee S, Kirchberger L, Montijn JS, Thamizharasu P, Camillo D, Levelt CN, Roelfsema PR, Self MW, Heimel JA. Curr Biol. 2019 Dec 16;29(24):4268-4275.e7. doi: 10.1016/j.cub.2019.10.037. Epub 2019 Nov 27. PubMed
Complementary Roles for Ventral Pallidum Cell Types and Their Projections in Relapse. Prasad AA, Xie C, Chaichim C, Nguyen JH, McClusky HE, Killcross S, Power JM, McNally GP. J Neurosci. 2020 Jan 22;40(4):880-893. doi: 10.1523/JNEUROSCI.0262-19.2019. Epub 2019 Dec 9. PubMed
NTS Catecholamine Neurons Mediate Hypoglycemic Hunger via Medial Hypothalamic Feeding Pathways. Aklan I, Sayar Atasoy N, Yavuz Y, Ates T, Coban I, Koksalar F, Filiz G, Topcu IC, Oncul M, Dilsiz P, Cebecioglu U, Alp MI, Yilmaz B, Davis DR, Hajdukiewicz K, Saito K, Konopka W, Cui H, Atasoy D. Cell Metab. 2020 Feb 4;31(2):313-326.e5. doi: 10.1016/j.cmet.2019.11.016. Epub 2019 Dec 12. PubMed
Dopaminergic and Prefrontal Basis of Learning from Sensory Confidence and Reward Value. Lak A, Okun M, Moss MM, Gurnani H, Farrell K, Wells MJ, Reddy CB, Kepecs A, Harris KD, Carandini M. Neuron. 2019 Dec 16. pii: S0896-6273(19)30982-1. doi: 10.1016/j.neuron.2019.11.018. PubMed
Activation of parvalbumin-expressing neurons reconfigures neuronal ensembles in murine striatal microcircuits. Duhne M, Lara-Gonzalez E, Laville A, Padilla-Orozco M, Avila-Cascajares F, Arias-Garcia M, Galarraga E, Bargas J. Eur J Neurosci. 2020 Jan 4. doi: 10.1111/ejn.14670. PubMed
Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy. Chen W, Cai ZL, Chao ES, Chen H, Longley CM, Hao S, Chao HT, Kim JH, Messier JE, Zoghbi HY, Tang J, Swann JW, Xue M. Elife. 2020 Feb 19;9. pii: 48705. doi: 10.7554/eLife.48705. PubMed

Associated Plasmids

A Novel Next-Generation Sequencing and Analysis Platform to Assess the Identity of Recombinant Adeno-Associated Viral Preparations from Viral DNA Extracts. Guerin K, Rego M, Bourges D, Ersing I, Haery L, Harten DeMaio K, Sanders E, Tasissa M, Kostman M, Tillgren M, Makana Hanley L, Mueller I, Mitsopoulos A, Fan M. Hum Gene Ther. 2020 Jun;31(11-12):664-678. doi: 10.1089/hum.2019.277. Epub 2020 Apr 15. PubMed
Divergent Neural Pathways Emanating from the Lateral Parabrachial Nucleus Mediate Distinct Components of the Pain Response. Chiang MC, Nguyen EK, Canto-Bustos M, Papale AE, Oswald AM, Ross SE. Neuron. 2020 Jun 17;106(6):927-939.e5. doi: 10.1016/j.neuron.2020.03.014. Epub 2020 Apr 13. PubMed
GAD2 Expression Defines a Class of Excitatory Lateral Habenula Neurons in Mice that Project to the Raphe and Pontine Tegmentum. Quina LA, Walker A, Morton G, Han V, Turner EE. eNeuro. 2020 May 20;7(3). pii: ENEURO.0527-19.2020. doi: 10.1523/ENEURO.0527-19.2020. Print 2020 May/Jun. PubMed
Frequency-dependent gating of feedforward inhibition in thalamofrontal synapses. Lee J, Choi JH, Rah JC. Mol Brain. 2020 May 6;13(1):68. doi: 10.1186/s13041-020-00608-2. PubMed
Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice. Haji N, Riebe I, Aguilar-Valles A, Artinian J, Laplante I, Lacaille JC. Mol Autism. 2020 May 6;11(1):29. doi: 10.1186/s13229-020-00340-7. PubMed
Nonspecific Expression in Limited Excitatory Cell Populations in Interneuron-Targeting Cre-driver Lines Can Have Large Functional Effects. Muller-Komorowska D, Opitz T, Elzoheiry S, Schweizer M, Ambrad Giovannetti E, Beck H. Front Neural Circuits. 2020 Apr 27;14:16. doi: 10.3389/fncir.2020.00016. eCollection 2020. PubMed
Perinatal interference with the serotonergic system affects VTA function in the adult via glutamate co-transmission. Cunha C, Smiley JF, Chuhma N, Shah R, Bleiwas C, Menezes EC, Seal RP, Edwards RH, Rayport S, Ansorge MS, Castellanos FX, Teixeira CM. Mol Psychiatry. 2021 Sep;26(9):4795-4812. doi: 10.1038/s41380-020-0763-z. Epub 2020 May 12. PubMed
Retinal innervation tunes circuits that drive nonphotic entrainment to food. Fernandez DC, Komal R, Langel J, Ma J, Duy PQ, Penzo MA, Zhao H, Hattar S. Nature. 2020 May;581(7807):194-198. doi: 10.1038/s41586-020-2204-1. Epub 2020 Apr 22. PubMed
Dopamine Inputs from the Ventral Tegmental Area into the Medial Prefrontal Cortex Modulate Neuropathic Pain-Associated Behaviors in Mice. Huang S, Zhang Z, Gambeta E, Xu SC, Thomas C, Godfrey N, Chen L, M'Dahoma S, Borgland SL, Zamponi GW. Cell Rep. 2020 Jun 23;31(12):107812. doi: 10.1016/j.celrep.2020.107812. PubMed
Anatomically and functionally distinct thalamocortical inputs to primary and secondary mouse whisker somatosensory cortices. El-Boustani S, Sermet BS, Foustoukos G, Oram TB, Yizhar O, Petersen CCH. Nat Commun. 2020 Jul 3;11(1):3342. doi: 10.1038/s41467-020-17087-7. PubMed
A Neuro-hormonal Circuit for Paternal Behavior Controlled by a Hypothalamic Network Oscillation. Stagkourakis S, Smiley KO, Williams P, Kakadellis S, Ziegler K, Bakker J, Brown RSE, Harkany T, Grattan DR, Broberger C. Cell. 2020 Aug 20;182(4):960-975.e15. doi: 10.1016/j.cell.2020.07.007. Epub 2020 Aug 6. PubMed
Identification of a brainstem locus that inhibits tumor necrosis factor. Kressel AM, Tsaava T, Levine YA, Chang EH, Addorisio ME, Chang Q, Burbach BJ, Carnevale D, Lembo G, Zador AM, Andersson U, Pavlov VA, Chavan SS, Tracey KJ. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29803-29810. doi: 10.1073/pnas.2008213117. Epub 2020 Nov 9. PubMed
Activation of Preoptic Arginine Vasopressin Neurons Induces Hyperthermia in Male Mice. Tabarean IV. Endocrinology. 2021 Feb 1;162(2). pii: 6010022. doi: 10.1210/endocr/bqaa217. PubMed
Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network. Yap EL, Pettit NL, Davis CP, Nagy MA, Harmin DA, Golden E, Dagliyan O, Lin C, Rudolph S, Sharma N, Griffith EC, Harvey CD, Greenberg ME. Nature. 2021 Feb;590(7844):115-121. doi: 10.1038/s41586-020-3031-0. Epub 2020 Dec 9. PubMed
An excitatory ventromedial hypothalamus to paraventricular thalamus circuit that suppresses food intake. Zhang J, Chen D, Sweeney P, Yang Y. Nat Commun. 2020 Dec 10;11(1):6326. doi: 10.1038/s41467-020-20093-4. PubMed
A Comparison of Dopaminergic and Cholinergic Populations Reveals Unique Contributions of VTA Dopamine Neurons to Short-Term Memory. Choi JY, Jang HJ, Ornelas S, Fleming WT, Furth D, Au J, Bandi A, Engel EA, Witten IB. Cell Rep. 2020 Dec 15;33(11):108492. doi: 10.1016/j.celrep.2020.108492. PubMed
Cell-type-specific nicotinic input disinhibits mouse barrel cortex during active sensing. Gasselin C, Hohl B, Vernet A, Crochet S, Petersen CCH. Neuron. 2021 Mar 3;109(5):778-787.e3. doi: 10.1016/j.neuron.2020.12.018. Epub 2021 Jan 19. PubMed
Soft subdermal implant capable of wireless battery charging and programmable controls for applications in optogenetics. Kim CY, Ku MJ, Qazi R, Nam HJ, Park JW, Nam KS, Oh S, Kang I, Jang JH, Kim WY, Kim JH, Jeong JW. Nat Commun. 2021 Jan 22;12(1):535. doi: 10.1038/s41467-020-20803-y. PubMed
Enhanced GABAergic Inhibition of Cholinergic Interneurons in the zQ175(+/-) Mouse Model of Huntington's Disease. Lim SAO, Surmeier DJ. Front Syst Neurosci. 2021 Jan 20;14:626412. doi: 10.3389/fnsys.2020.626412. eCollection 2020. PubMed
Loss of nigral excitation of cholinergic interneurons contributes to parkinsonian motor impairments. Cai Y, Nielsen BE, Boxer EE, Aoto J, Ford CP. Neuron. 2021 Apr 7;109(7):1137-1149.e5. doi: 10.1016/j.neuron.2021.01.028. Epub 2021 Feb 17. PubMed

Associated Plasmids

Gamma rhythms and visual information in mouse V1 specifically modulated by somatostatin(+) neurons in reticular thalamus. Hoseini MS, Higashikubo B, Cho FS, Chang AH, Clemente-Perez A, Lew I, Ciesielska A, Stryker MP, Paz JT. Elife. 2021 Apr 12;10. pii: 61437. doi: 10.7554/eLife.61437. PubMed
Autonomous Purkinje cell activation instructs bidirectional motor learning through evoked dendritic calcium signaling. Bonnan A, Rowan MMJ, Baker CA, Bolton MM, Christie JM. Nat Commun. 2021 Apr 12;12(1):2153. doi: 10.1038/s41467-021-22405-8. PubMed
Diversity in striatal synaptic circuits arises from distinct embryonic progenitor pools in the ventral telencephalon. van Heusden F, Macey-Dare A, Gordon J, Krajeski R, Sharott A, Ellender T. Cell Rep. 2021 Apr 27;35(4):109041. doi: 10.1016/j.celrep.2021.109041. PubMed
Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1. Robert V, Therreau L, Chevaleyre V, Lepicard E, Viollet C, Cognet J, Huang AJ, Boehringer R, Polygalov D, McHugh TJ, Piskorowski RA. Elife. 2021 May 18;10. pii: 63352. doi: 10.7554/eLife.63352. PubMed
Food cue regulation of AGRP hunger neurons guides learning Berrios J, Li C, Madara JC, Garfield AS, Steger JS, Krashes MJ, Lowell BB. Nature. 2021 Jul;595(7869):695-700. doi: 10.1038/s41586-021-03729-3. Epub 2021 Jul 14. PubMed
Bottom-up inputs are required for establishment of top-down connectivity onto cortical layer 1 neurogliaform cells. Ibrahim LA, Huang S, Fernandez-Otero M, Sherer M, Qiu Y, Vemuri S, Xu Q, Machold R, Pouchelon G, Rudy B, Fishell G. Neuron. 2021 Nov 3;109(21):3473-3485.e5. doi: 10.1016/j.neuron.2021.08.004. Epub 2021 Sep 2. PubMed
Single-cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin-driven circadian network. Morris EL, Patton AP, Chesham JE, Crisp A, Adamson A, Hastings MH. EMBO J. 2021 Oct 18;40(20):e108614. doi: 10.15252/embj.2021108614. Epub 2021 Sep 6. PubMed
Activation of septal OXTr neurons induces anxiety- but not depressive-like behaviors. Huang T, Guan F, Licinio J, Wong ML, Yang Y. Mol Psychiatry. 2021 Dec;26(12):7270-7279. doi: 10.1038/s41380-021-01283-y. Epub 2021 Sep 6. PubMed
Restoration of Visual Function and Cortical Connectivity After Ischemic Injury Through NeuroD1-Mediated Gene Therapy. Tang Y, Wu Q, Gao M, Ryu E, Pei Z, Kissinger ST, Chen Y, Rao AK, Xiang Z, Wang T, Li W, Chen G, Chubykin AA. Front Cell Dev Biol. 2021 Aug 18;9:720078. doi: 10.3389/fcell.2021.720078. eCollection 2021. PubMed
Glucagon-like peptide-1 (GLP-1) signalling in the brain: From neural circuits and metabolism to therapeutics. Kabahizi A, Wallace B, Lieu L, Chau D, Dong Y, Hwang ES, Williams KW. Br J Pharmacol. 2022 Feb;179(4):600-624. doi: 10.1111/bph.15682. Epub 2021 Nov 4. PubMed
Flexible inhibitory control of visually evoked defensive behavior by the ventral lateral geniculate nucleus. Fratzl A, Koltchev AM, Vissers N, Tan YL, Marques-Smith A, Stempel AV, Branco T, Hofer SB. Neuron. 2021 Dec 1;109(23):3810-3822.e9. doi: 10.1016/j.neuron.2021.09.003. Epub 2021 Oct 5. PubMed
The mouse cortico-basal ganglia-thalamic network. Foster NN, Barry J, Korobkova L, Garcia L, Gao L, Becerra M, Sherafat Y, Peng B, Li X, Choi JH, Gou L, Zingg B, Azam S, Lo D, Khanjani N, Zhang B, Stanis J, Bowman I, Cotter K, Cao C, Yamashita S, Tugangui A, Li A, Jiang T, Jia X, Feng Z, Aquino S, Mun HS, Zhu M, Santarelli A, Benavidez NL, Song M, Dan G, Fayzullina M, Ustrell S, Boesen T, Johnson DL, Xu H, Bienkowski MS, Yang XW, Gong H, Levine MS, Wickersham I, Luo Q, Hahn JD, Lim BK, Zhang LI, Cepeda C, Hintiryan H, Dong HW. Nature. 2021 Oct;598(7879):188-194. doi: 10.1038/s41586-021-03993-3. Epub 2021 Oct 6. PubMed
Modulation of tactile feedback for the execution of dexterous movement. Conner JM, Bohannon A, Igarashi M, Taniguchi J, Baltar N, Azim E. Science. 2021 Oct 15;374(6565):316-323. doi: 10.1126/science.abh1123. Epub 2021 Oct 14. PubMed
Control of parallel hippocampal output pathways by amygdalar long-range inhibition. AlSubaie R, Wee RW, Ritoux A, Mishchanchuk K, Passlack J, Regester D, MacAskill AF. Elife. 2021 Nov 30;10. pii: 74758. doi: 10.7554/eLife.74758. PubMed
Retinal horizontal cells use different synaptic sites for global feedforward and local feedback signaling. Behrens C, Yadav SC, Korympidou MM, Zhang Y, Haverkamp S, Irsen S, Schaedler A, Lu X, Liu Z, Lause J, St-Pierre F, Franke K, Vlasits A, Dedek K, Smith RG, Euler T, Berens P, Schubert T. Curr Biol. 2022 Feb 7;32(3):545-558.e5. doi: 10.1016/j.cub.2021.11.055. Epub 2021 Dec 14. PubMed
Divergent brainstem opioidergic pathways that coordinate breathing with pain and emotions. Liu S, Ye M, Pao GM, Song SM, Jhang J, Jiang H, Kim JH, Kang SJ, Kim DI, Han S. Neuron. 2022 Mar 2;110(5):857-873.e9. doi: 10.1016/j.neuron.2021.11.029. Epub 2021 Dec 17. PubMed
Myelination synchronizes cortical oscillations by consolidating parvalbumin-mediated phasic inhibition. Dubey M, Pascual-Garcia M, Helmes K, Wever DD, Hamada MS, Kushner SA, Kole MHP. Elife. 2022 Jan 10;11. pii: 73827. doi: 10.7554/eLife.73827. PubMed
Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons. Joffe ME, Maksymetz J, Luschinger JR, Dogra S, Ferranti AS, Luessen DJ, Gallinger IM, Xiang Z, Branthwaite H, Melugin PR, Williford KM, Centanni SW, Shields BC, Lindsley CW, Calipari ES, Siciliano CA, Niswender CM, Tadross MR, Winder DG, Conn PJ. Neuron. 2022 Mar 16;110(6):1068-1083.e5. doi: 10.1016/j.neuron.2021.12.027. Epub 2022 Jan 18. PubMed
A New Player in the Hippocampus: A Review on VGLUT3+ Neurons and Their Role in the Regulation of Hippocampal Activity and Behaviour. Fazekas CL, Szabo A, Torok B, Banrevi K, Correia P, Chaves T, Daumas S, Zelena D. Int J Mol Sci. 2022 Jan 12;23(2). pii: ijms23020790. doi: 10.3390/ijms23020790. PubMed
Median Raphe Nonserotonergic Neurons Modulate Hippocampal Theta Oscillations. Huang W, Ikemoto S, Wang DV. J Neurosci. 2022 Mar 9;42(10):1987-1998. doi: 10.1523/JNEUROSCI.1536-21.2022. Epub 2022 Jan 21. PubMed
Amygdala Underlies the Environment Dependency of Defense Responses Induced via Superior Colliculus. Isa K, Tokuoka K, Ikeda S, Karimi S, Kobayashi K, Sooksawate T, Isa T. Front Neural Circuits. 2022 Jan 7;15:768647. doi: 10.3389/fncir.2021.768647. eCollection 2021. PubMed
Juxtacellular opto-tagging of hippocampal CA1 neurons in freely moving mice. Ding L, Balsamo G, Chen H, Blanco-Hernandez E, Zouridis IS, Naumann R, Preston-Ferrer P, Burgalossi A. Elife. 2022 Jan 26;11. pii: 71720. doi: 10.7554/eLife.71720. PubMed
Prolactin-mediated restraint of maternal aggression in lactation. Georgescu T, Khant Aung Z, Grattan DR, Brown RSE. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2116972119. doi: 10.1073/pnas.2116972119. PubMed
A vibrissa pathway that activates the limbic system. Elbaz M, Callado Perez A, Demers M, Zhao S, Foo C, Kleinfeld D, Deschenes M. Elife. 2022 Feb 10;11. pii: 72096. doi: 10.7554/eLife.72096. PubMed
The Long and Winding Road-Vestibular Efferent Anatomy in Mice. Lorincz D, Poppi LA, Holt JC, Drury HR, Lim R, Brichta AM. Front Neural Circuits. 2022 Jan 28;15:751850. doi: 10.3389/fncir.2021.751850. eCollection 2021. PubMed
Whole-brain opto-fMRI map of mouse VTA dopaminergic activation reflects structural projections with small but significant deviations. Ioanas HI, Saab BJ, Rudin M. Transl Psychiatry. 2022 Feb 14;12(1):60. doi: 10.1038/s41398-022-01812-5. PubMed
Target-specific control of olfactory bulb periglomerular cells by GABAergic and cholinergic basal forebrain inputs. De Saint Jan D. Elife. 2022 Feb 28;11:e71965. doi: 10.7554/eLife.71965. PubMed
Cortico-striatal circuits for bilaterally coordinated movements. Pimentel-Farfan AK, Baez-Cordero AS, Pena-Rangel TM, Rueda-Orozco PE. Sci Adv. 2022 Mar 4;8(9):eabk2241. doi: 10.1126/sciadv.abk2241. Epub 2022 Mar 4. PubMed
A bottom-up reward pathway mediated by somatostatin neurons in the medial septum complex underlying appetitive learning. Shen L, Zhang GW, Tao C, Seo MB, Zhang NK, Huang JJ, Zhang LI, Tao HW. Nat Commun. 2022 Mar 7;13(1):1194. doi: 10.1038/s41467-022-28854-z. PubMed
Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions. Roy DS, Park YG, Kim ME, Zhang Y, Ogawa SK, DiNapoli N, Gu X, Cho JH, Choi H, Kamentsky L, Martin J, Mosto O, Aida T, Chung K, Tonegawa S. Nat Commun. 2022 Apr 4;13(1):1799. doi: 10.1038/s41467-022-29384-4. PubMed
Dopaminergic regulation of vestibulo-cerebellar circuits through unipolar brush cells. Canton-Josh JE, Qin J, Salvo J, Kozorovitskiy Y. Elife. 2022 Apr 27;11. pii: 76912. doi: 10.7554/eLife.76912. PubMed
Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Burke DA, Alvarez VA. Cell Rep. 2022 May 10;39(6):110795. doi: 10.1016/j.celrep.2022.110795. PubMed
Divergent properties and independent regulation of striatal dopamine and GABA co-transmission. Zych SM, Ford CP. Cell Rep. 2022 May 17;39(7):110823. doi: 10.1016/j.celrep.2022.110823. PubMed
Conserved patterns of functional organization between cortex and thalamus in mice. Miller-Hansen AJ, Sherman SM. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2201481119. doi: 10.1073/pnas.2201481119. Epub 2022 May 19. PubMed
Stimulation of medial amygdala GABA neurons with kinetically different channelrhodopsins yields opposite behavioral outcomes. Baleisyte A, Schneggenburger R, Kochubey O. Cell Rep. 2022 May 24;39(8):110850. doi: 10.1016/j.celrep.2022.110850. PubMed
Cholinergic interneurons mediate cocaine extinction in male mice through plasticity across medium spiny neuron subtypes. Fleming W, Lee J, Briones BA, Bolkan SS, Witten IB. Cell Rep. 2022 May 31;39(9):110874. doi: 10.1016/j.celrep.2022.110874. PubMed
Sparse genetically defined neurons refine the canonical role of periaqueductal gray columnar organization. La-Vu MQ, Sethi E, Maesta-Pereira S, Schuette PJ, Tobias BC, Reis FMCV, Wang W, Torossian A, Bishop A, Leonard SJ, Lin L, Cahill CM, Adhikari A. Elife. 2022 Jun 8;11. pii: 77115. doi: 10.7554/eLife.77115. PubMed
State-dependent activity dynamics of hypothalamic stress effector neurons. Ichiyama A, Mestern S, Benigno GB, Scott KE, Allman BL, Muller L, Inoue W. Elife. 2022 Jun 30;11:e76832. doi: 10.7554/eLife.76832. PubMed
Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis. Upchurch CM, Yeudall S, Pavelec CM, Merk D, Greulich J, Manjegowda M, Raghavan SS, Bochkis IM, Scott MM, Perez-Reyes E, Leitinger N. Sci Adv. 2022 Jul 15;8(28):eabn0050. doi: 10.1126/sciadv.abn0050. Epub 2022 Jul 15. PubMed
Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice. Takahashi A, Durand-de Cuttoli R, Flanigan ME, Hasegawa E, Tsunematsu T, Aleyasin H, Cherasse Y, Miya K, Okada T, Keino-Masu K, Mitsui K, Li L, Patel V, Blitzer RD, Lazarus M, Tanaka KF, Yamanaka A, Sakurai T, Ogawa S, Russo SJ. Nat Commun. 2022 Jul 21;13(1):4039. doi: 10.1038/s41467-022-31728-z. PubMed
Dynamic control of visually guided locomotion through corticosubthalamic projections. Adam EM, Johns T, Sur M. Cell Rep. 2022 Jul 26;40(4):111139. doi: 10.1016/j.celrep.2022.111139. PubMed
Control of fear by discrete prefrontal GABAergic populations encoding valence-specific information. Cummings KA, Bayshtok S, Dong TN, Kenny PJ, Clem RL. Neuron. 2022 Sep 21;110(18):3036-3052.e5. doi: 10.1016/j.neuron.2022.07.004. Epub 2022 Aug 8. PubMed
Microglia contribute to the postnatal development of cortical somatostatin-positive inhibitory cells and to whisker-evoked cortical activity. Gesuita L, Cavaccini A, Argunsah AO, Favuzzi E, Ibrahim LA, Stachniak TJ, De Gennaro M, Utz S, Greter M, Karayannis T. Cell Rep. 2022 Aug 16;40(7):111209. doi: 10.1016/j.celrep.2022.111209. PubMed
Properties and modulation of excitatory inputs to the locus coeruleus. Barcomb K, Olah SS, Kennedy MJ, Ford CP. J Physiol. 2022 Nov;600(22):4897-4916. doi: 10.1113/JP283605. Epub 2022 Oct 13. PubMed
Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward. Abraham AD, Casello SM, Land BB, Chavkin C. Addict Neurosci. 2022 Mar;1:100005. doi: 10.1016/j.addicn.2022.100005. Epub 2022 Jan 25. PubMed
Visual Deprivation Selectively Reduces Thalamic Reticular Nucleus-Mediated Inhibition of the Auditory Thalamus in Adults. Whitt JL, Ewall G, Chakraborty D, Adegbesan A, Lee R, Kanold PO, Lee HK. J Neurosci. 2022 Oct 19;42(42):7921-7930. doi: 10.1523/JNEUROSCI.2032-21.2022. Epub 2022 Sep 7. PubMed
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis. Furlan A, Corona A, Boyle S, Sharma R, Rubino R, Habel J, Gablenz EC, Giovanniello J, Beyaz S, Janowitz T, Shea SD, Li B. Nat Neurosci. 2022 Nov;25(11):1470-1480. doi: 10.1038/s41593-022-01178-3. Epub 2022 Oct 20. PubMed
Lateral septum modulates cortical state to tune responsivity to threat stimuli. Hashimoto M, Brito SI, Venner A, Pasqualini AL, Yang TL, Allen D, Fuller PM, Anthony TE. Cell Rep. 2022 Oct 25;41(4):111521. doi: 10.1016/j.celrep.2022.111521. PubMed
GnRH pulse generator frequency is modulated by kisspeptin and GABA-glutamate interactions in the posterodorsal medial amygdala in female mice. Lass G, Li XF, Voliotis M, Wall E, de Burgh RA, Ivanova D, McIntyre C, Lin XH, Colledge WH, Lightman SL, Tsaneva-Atanasova K, O'Byrne KT. J Neuroendocrinol. 2022 Nov;34(11):e13207. doi: 10.1111/jne.13207. Epub 2022 Oct 28. PubMed
Raphe serotonin projections dynamically regulate feeding behavior through targeting inhibitory circuits from rostral zona incerta to paraventricular thalamus. Ye Q, Nunez J, Zhang X. Mol Metab. 2022 Dec;66:101634. doi: 10.1016/j.molmet.2022.101634. Epub 2022 Nov 10. PubMed
A Cre-driver rat model for anatomical and functional analysis of glucagon (Gcg)-expressing cells in the brain and periphery. Zheng H, Lopez-Ferreras L, Krieger JP, Fasul S, Cea Salazar V, Valderrama Pena N, Skibicka KP, Rinaman L. Mol Metab. 2022 Dec;66:101631. doi: 10.1016/j.molmet.2022.101631. Epub 2022 Nov 8. PubMed
Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction. Schneeberger M, Brice NL, Pellegrino K, Parolari L, Shaked JT, Page KJ, Marchildon F, Barrows DW, Carroll TS, Topilko T, Mulligan VM, Newman R, Doyle K, Burli R, Barker DF, Glen A, Ortuno MJ, Nectow AR, Renier N, Cohen P, Carlton M, Heintz N, Friedman JM. Nat Metab. 2022 Nov;4(11):1495-1513. doi: 10.1038/s42255-022-00677-8. Epub 2022 Nov 21. PubMed
Rostral and caudal basolateral amygdala engage distinct circuits in the prelimbic and infralimbic prefrontal cortex. Manoocheri K, Carter AG. Elife. 2022 Dec 7;11:e82688. doi: 10.7554/eLife.82688. PubMed
Circuit-selective cell-autonomous regulation of inhibition in pyramidal neurons by Ste20-like kinase. Royero P, Quatraccioni A, Frungel R, Silva MH, Bast A, Ulas T, Beyer M, Opitz T, Schultze JL, Graham ME, Oberlaender M, Becker A, Schoch S, Beck H. Cell Rep. 2022 Dec 6;41(10):111757. doi: 10.1016/j.celrep.2022.111757. PubMed
Control of Emotion and Wakefulness by Neurotensinergic Neurons in the Parabrachial Nucleus. Chen J, Gannot N, Li X, Zhu R, Zhang C, Li P. Neurosci Bull. 2023 Apr;39(4):589-601. doi: 10.1007/s12264-022-00994-8. Epub 2022 Dec 16. PubMed
Region-selective control of the thalamic reticular nucleus via cortical layer 5 pyramidal cells. Hadinger N, Bosz E, Toth B, Vantomme G, Luthi A, Acsady L. Nat Neurosci. 2023 Jan;26(1):116-130. doi: 10.1038/s41593-022-01217-z. Epub 2022 Dec 22. PubMed
Structural and functional map for forelimb movement phases between cortex and medulla. Yang W, Kanodia H, Arber S. Cell. 2023 Jan 5;186(1):162-177.e18. doi: 10.1016/j.cell.2022.12.009. PubMed
Histamine Release in the Prefrontal Cortex Excites Fast-Spiking Interneurons while GABA Released from the Same Axons Inhibits Pyramidal Cells. Lucaci D, Yu X, Chadderton P, Wisden W, Brickley SG. J Neurosci. 2023 Jan 11;43(2):187-198. doi: 10.1523/JNEUROSCI.0936-22.2022. Epub 2022 Dec 8. PubMed
A Novel Single Vector Intersectional AAV Strategy for Interrogating Cellular Diversity and Brain Function. Hughes AC, Pollard BG, Xu B, Gammons JW, Chapman P, Bikoff JB, Schwarz LA. bioRxiv. 2023 Feb 8:2023.02.07.527312. doi: 10.1101/2023.02.07.527312. Preprint. PubMed

Associated Plasmids

D1 and D2 neurons in the nucleus accumbens enable positive and negative control over sugar intake in mice. Sandoval-Rodriguez R, Parra-Reyes JA, Han W, Rueda-Orozco PE, Perez IO, de Araujo IE, Tellez LA. Cell Rep. 2023 Mar 28;42(3):112190. doi: 10.1016/j.celrep.2023.112190. Epub 2023 Feb 28. PubMed
Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice. Pancani T, Day M, Tkatch T, Wokosin DL, Gonzalez-Rodriguez P, Kondapalli J, Xie Z, Chen Y, Beaumont V, Surmeier DJ. Nat Commun. 2023 Mar 14;14(1):1398. doi: 10.1038/s41467-023-36556-3. PubMed
Lateral hypothalamic leptin receptor neurons drive hunger-gated food-seeking and consummatory behaviours in male mice. Lee YH, Kim YB, Kim KS, Jang M, Song HY, Jung SH, Ha DS, Park JS, Lee J, Kim KM, Cheon DH, Baek I, Shin MG, Lee EJ, Kim SJ, Choi HJ. Nat Commun. 2023 Mar 17;14(1):1486. doi: 10.1038/s41467-023-37044-4. PubMed
Neural mechanism of acute stress regulation by trace aminergic signalling in the lateral habenula in male mice. Yang SH, Yang E, Lee J, Kim JY, Yoo H, Park HS, Jung JT, Lee D, Chun S, Jo YS, Pyeon GH, Park JY, Lee HW, Kim H. Nat Commun. 2023 Apr 27;14(1):2435. doi: 10.1038/s41467-023-38180-7. PubMed
Lateral septum as a melanocortin downstream site in obesity development. Xu Y, Jiang Z, Li H, Cai J, Jiang Y, Otiz-Guzman J, Xu Y, Arenkiel BR, Tong Q. Cell Rep. 2023 May 30;42(5):112502. doi: 10.1016/j.celrep.2023.112502. Epub 2023 May 11. PubMed
Asymmetric control of food intake by left and right vagal sensory neurons. de Araujo AM, Braga I, Leme G, Singh A, McDougle M, Smith J, Vergara M, Yang M, Lin M, Khoshbouei H, Krause E, de Oliveira AG, de Lartigue G. bioRxiv [Preprint]. 2023 May 8:2023.05.08.539627. doi: 10.1101/2023.05.08.539627. PubMed
Dual Roles for Nucleus Accumbens Core Dopamine D1-Expressing Neurons Projecting to the Substantia Nigra Pars Reticulata in Limbic and Motor Control in Male Mice. Attachaipanich S, Ozawa T, Macpherson T, Hikida T. eNeuro. 2023 Jun 6;10(6):ENEURO.0082-23.2023. doi: 10.1523/ENEURO.0082-23.2023. Print 2023 Jun. PubMed
Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling. Boyle KA, Polgar E, Gutierrez-Mecinas M, Dickie AC, Cooper AH, Bell AM, Jumolea E, Casas-Benito A, Watanabe M, Hughes DI, Weir GA, Riddell JS, Todd AJ. Elife. 2023 Jul 25;12:RP86633. doi: 10.7554/eLife.86633. PubMed
Drug-Inducible Gene Therapy Effectively Reduces Spontaneous Seizures in Kindled Rats but Creates Off-Target Side Effects in Inhibitory Neurons. Sullivan KA, Vitko I, Blair K, Gaykema RP, Failor MJ, San Pietro JM, Dey D, Williamson JM, Stornetta RL, Kapur J, Perez-Reyes E. Int J Mol Sci. 2023 Jul 12;24(14):11347. doi: 10.3390/ijms241411347. PubMed
Somatostatin neurons in prefrontal cortex initiate sleep-preparatory behavior and sleep via the preoptic and lateral hypothalamus. Tossell K, Yu X, Giannos P, Anuncibay Soto B, Nollet M, Yustos R, Miracca G, Vicente M, Miao A, Hsieh B, Ma Y, Vyssotski AL, Constandinou T, Franks NP, Wisden W. Nat Neurosci. 2023 Oct;26(10):1805-1819. doi: 10.1038/s41593-023-01430-4. Epub 2023 Sep 21. PubMed
Widefield imaging of rapid pan-cortical voltage dynamics with an indicator evolved for one-photon microscopy. Lu X, Wang Y, Liu Z, Gou Y, Jaeger D, St-Pierre F. Nat Commun. 2023 Oct 12;14(1):6423. doi: 10.1038/s41467-023-41975-3. PubMed

Associated Plasmids

Movement-related increases in subthalamic activity optimize locomotion. Callahan JW, Morales JC, Atherton JF, Wang D, Kostic S, Bevan MD. bioRxiv [Preprint]. 2024 May 28:2023.12.07.570617. doi: 10.1101/2023.12.07.570617. PubMed
Frequency Specific Optogenetic Stimulation of the Locus Coeruleus Induces Task-Relevant Plasticity in the Motor Cortex. Tseng CT, Welch HF, Gi AL, Kang EM, Mamidi T, Pydimarri S, Ramesh K, Sandoval A, Ploski JE, Thorn CA. J Neurosci. 2024 Feb 14;44(7):e1528232023. doi: 10.1523/JNEUROSCI.1528-23.2023. PubMed
Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits. Pratelli M, Hakimi AM, Thaker A, Li HQ, Godavarthi SK, Spitzer NC. Res Sq [Preprint]. 2023 Dec 13:rs.3.rs-3689243. doi: 10.21203/rs.3.rs-3689243/v1. PubMed
Projection-Targeted Photopharmacology Reveals Distinct Anxiolytic Roles for Presynaptic mGluR2 in Prefrontal- and Insula-Amygdala Synapses. Munguba H, Gutzeit VA, Srivastava I, Kristt M, Singh A, Vijay A, Arefin A, Thukral S, Broichhagen J, Stujenske JM, Liston C, Levitz J. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575699. doi: 10.1101/2024.01.15.575699. PubMed
Chemo- and optogenetic activation of hypothalamic Foxb1-expressing neurons and their terminal endings in the rostral-dorsolateral PAG leads to tachypnea, bradycardia, and immobility. Cola RB, Roccaro-Waldmeyer DM, Naim S, Babalian A, Seebeck P, Alvarez-Bolado G, Celio MR. Elife. 2024 Feb 1;12:RP86737. doi: 10.7554/eLife.86737. PubMed
Basal ganglia-spinal cord pathway that commands locomotor gait asymmetries in mice. Cregg JM, Sidhu SK, Leiras R, Kiehn O. Nat Neurosci. 2024 Apr;27(4):716-727. doi: 10.1038/s41593-024-01569-8. Epub 2024 Feb 12. PubMed
Optogenetic stimulation of neurons in the anterior cingulate cortex induces changes in intravesical bladder pressure and the micturition reflex. Mochizuki T, Manita S, Shimura H, Kira S, Sawada N, Bito H, Sakimura K, Augustine GJ, Mitsui T, Takeda M, Kitamura K. Sci Rep. 2024 Mar 16;14(1):6367. doi: 10.1038/s41598-024-56806-8. PubMed
Long-range inhibitory neurons mediate cortical neurovascular coupling. Ruff CF, Juarez Anaya F, Dienel SJ, Rakymzhan A, Altamirano-Espinoza A, Couey JJ, Fukuda M, Watson AM, Su A, Fish KN, Rubio ME, Hooks BM, Ross SE, Vazquez AL. Cell Rep. 2024 Apr 23;43(4):113970. doi: 10.1016/j.celrep.2024.113970. Epub 2024 Mar 19. PubMed
State-dependent central synaptic regulation by GLP-1 is essential for energy homeostasis. Wang L, Savani R, Bernabucci M, Lu Y, Singh I, Xu W, El Ouaamari A, Wheeler MB, Grill HJ, Rossi MA, Pang ZP. Res Sq [Preprint]. 2024 Mar 12:rs.3.rs-3929981. doi: 10.21203/rs.3.rs-3929981/v1. PubMed
Convergence of inputs from the basal ganglia with layer 5 of motor cortex and cerebellum in mouse motor thalamus. Koster KP, Sherman SM. bioRxiv [Preprint]. 2024 Mar 14:2024.03.14.584958. doi: 10.1101/2024.03.14.584958. PubMed
Selective plasticity of layer 2/3 inputs onto distal forelimb controlling layer 5 corticospinal neurons with skilled grasp motor training. Takashima Y, Biane JS, Tuszynski MH. Cell Rep. 2024 Apr 23;43(4):113986. doi: 10.1016/j.celrep.2024.113986. Epub 2024 Apr 9. PubMed
The mouse dorsal peduncular cortex encodes fear memory. Campos-Cardoso R, Desa ZR, Fitzgerald BL, Moore AG, Duhon JL, Landar VA, Clem RL, Cummings KA. Cell Rep. 2024 Apr 23;43(4):114097. doi: 10.1016/j.celrep.2024.114097. Epub 2024 Apr 12. PubMed
Opposing actions of co-released GABA and neurotensin on the activity of preoptic neurons and on body temperature. Tabarean IV. bioRxiv [Preprint]. 2024 Apr 17:2024.04.15.589556. doi: 10.1101/2024.04.15.589556. PubMed
Higher-order thalamocortical circuits are specified by embryonic cortical progenitor types in the mouse brain. Buchan MJ, Gothard G, Mahfooz K, van Rheede JJ, Avery SV, Vourvoukelis A, Demby A, Ellender TJ, Newey SE, Akerman CJ. Cell Rep. 2024 May 28;43(5):114157. doi: 10.1016/j.celrep.2024.114157. Epub 2024 Apr 26. PubMed
The type of inhibition provided by thalamic interneurons alters the input selectivity of thalamocortical neurons. Djama D, Zirpel F, Ye Z, Moore G, Chue C, Edge C, Jager P, Delogu A, Brickley SG. Curr Res Neurobiol. 2024 Apr 20;6:100130. doi: 10.1016/j.crneur.2024.100130. eCollection 2024. PubMed
A vasopressin circuit that modulates mouse social investigation and anxiety-like behavior in a sex-specific manner. Rigney N, Campos-Lira E, Kirchner MK, Wei W, Belkasim S, Beaumont R, Singh S, Suarez SG, Hartswick D, Stern JE, de Vries GJ, Petrulis A. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2319641121. doi: 10.1073/pnas.2319641121. Epub 2024 May 6. PubMed
Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scales. Crombie D, Spacek MA, Leibold C, Busse L. PLoS Biol. 2024 May 14;22(5):e3002614. doi: 10.1371/journal.pbio.3002614. eCollection 2024 May. PubMed
Dorsolateral septum GLP-1R neurons regulate feeding via lateral hypothalamic projections. Lu Y, Wang L, Luo F, Savani R, Rossi MA, Pang ZP. Mol Metab. 2024 Jul;85:101960. doi: 10.1016/j.molmet.2024.101960. Epub 2024 May 17. PubMed
Coexistence of state, choice, and sensory integration coding in barrel cortex LII/III. Garderes PM, Le Gal S, Rousseau C, Mamane A, Ganea DA, Haiss F. Nat Commun. 2024 Jun 5;15(1):4782. doi: 10.1038/s41467-024-49129-9. PubMed
Parvalbumin-expressing basal forebrain neurons mediate learning from negative experience. Hegedus P, Kiraly B, Schlingloff D, Lyakhova V, Velencei A, Szabo I, Mayer MI, Zelenak Z, Nyiri G, Hangya B. Nat Commun. 2024 Jun 7;15(1):4768. doi: 10.1038/s41467-024-48755-7. PubMed
Expression of GAD2 in excitatory neurons projecting from the ventrolateral periaqueductal gray to the locus coeruleus. Harding EK, Zhang Z, Canet-Pons J, Stokes-Heck S, Trang T, Zamponi GW. iScience. 2024 May 16;27(6):109972. doi: 10.1016/j.isci.2024.109972. eCollection 2024 Jun 21. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.