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The Human Druggable CRISPR Library
(Pooled Library #200013)

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  • Purpose

    The CRISPR knockout library contains ~10,000 sgRNAs targeting 1,980 human druggable genes (five sgRNAs per gene and 100 non-targeting control sgRNAs).

  • Vector Backbone

    lentiCRISPR v2 (Plasmid #52961) - expresses Cas9

Ordering

Item Catalog # Description Quantity Price (USD)
Pooled Library 200013 Human Druggable CRISPR Library 1 $430 Add to Cart
Available to Academic and Nonprofits Only

Library Details

  • Species
    Human
  • Genes targeted
    1,980
  • gRNAs
    10,000
  • Controls
    100
  • Lentiviral Generation
    3rd

Library Shipping

This library is delivered as suspended DNA in a microcentrifuge tube on blue ice. The tube's contents will not necessarily be frozen. For best results, minimize freeze/thaws.

  • Volume
    ∼20 µL
  • Concentration
    50 ng/µL

Resource Information

Depositor Comments

Figure 1. Contents of the Human Druggable CRISPR library.

The depositing lab recommends using MAGeCK algorithms (Link opens in a new window)for analysis.

How to cite this pooled library ( Back to top )

These pooled libraries were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications.

  • For your Materials & Methods section:

    The Human Druggable CRISPR library was a gift from Lianxin Liu (Addgene #200013)

  • For your References section:

    Donafenib and GSK-J4 Synergistically Induce Ferroptosis in Liver Cancer by Upregulating HMOX1 Expression. Zheng C, Zhang B, Li Y, Liu K, Wei W, Liang S, Guo H, Ma K, Liu Y, Wang J, Liu L. Adv Sci (Weinh). 2023 Aug;10(22):e2206798. doi: 10.1002/advs.202206798. PubMed 37330650
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