HA-VHL-pRc/CMV Citations (12)

Originally described in: Tumour suppression by the human von Hippel-Lindau gene product.
Iliopoulos O, Kibel A, Gray S, Kaelin WG Nat Med. 1995 Aug . 1(8):822-6. PubMed Journal

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Articles Citing HA-VHL-pRc/CMV

Articles
ERK5/BMK1 is a novel target of the tumor suppressor VHL: implication in clear cell renal carcinoma. Arias-Gonzalez L, Moreno-Gimeno I, del Campo AR, Serrano-Oviedo L, Valero ML, Esparis-Ogando A, de la Cruz-Morcillo MA, Melgar-Rojas P, Garcia-Cano J, Cimas FJ, Hidalgo MJ, Prado A, Callejas-Valera JL, Nam-Cha SH, Gimenez-Bachs JM, Salinas-Sanchez AS, Pandiella A, del Peso L, Sanchez-Prieto R. Neoplasia. 2013 Jun;15(6):649-59. PubMed
Glutathione adducts induced by ischemia and deletion of glutaredoxin-1 stabilize HIF-1alpha and improve limb revascularization. Watanabe Y, Murdoch CE, Sano S, Ido Y, Bachschmid MM, Cohen RA, Matsui R. Proc Natl Acad Sci U S A. 2016 May 24;113(21):6011-6. doi: 10.1073/pnas.1524198113. Epub 2016 May 9. PubMed
Protein 4.1R Influences Myogenin Protein Stability and Skeletal Muscle Differentiation. Huang SC, Zhou A, Nguyen DT, Zhang HS, Benz EJ Jr. J Biol Chem. 2016 Dec 2;291(49):25591-25607. Epub 2016 Oct 25. PubMed
VHL promotes immune response against renal cell carcinoma via NF-kappaB-dependent regulation of VCAM-1. Labrousse-Arias D, Martinez-Alonso E, Corral-Escariz M, Bienes-Martinez R, Berridy J, Serrano-Oviedo L, Conde E, Garcia-Bermejo ML, Gimenez-Bachs JM, Salinas-Sanchez AS, Sanchez-Prieto R, Yao M, Lasa M, Calzada MJ. J Cell Biol. 2017 Mar 6;216(3):835-847. doi: 10.1083/jcb.201608024. Epub 2017 Feb 24. PubMed
XIAP upregulates expression of HIF target genes by targeting HIF1alpha for Lys63-linked polyubiquitination. Park CV, Ivanova IG, Kenneth NS. Nucleic Acids Res. 2017 Jun 28. doi: 10.1093/nar/gkx549. PubMed
SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2alpha. Mira E, Carmona-Rodriguez L, Perez-Villamil B, Casas J, Fernandez-Acenero MJ, Martinez-Rey D, Martin-Gonzalez P, Heras-Murillo I, Paz-Cabezas M, Tardaguila M, Oury TD, Martin-Puig S, Lacalle RA, Fabrias G, Diaz-Rubio E, Manes S. Nat Commun. 2018 Feb 8;9(1):575. doi: 10.1038/s41467-018-03079-1. PubMed
pVHL-mediated regulation of the anti-angiogenic protein thrombospondin-1 decreases migration of Clear Cell Renal Carcinoma Cell Lines. Sevilla-Montero J, Bienes-Martinez R, Labrousse-Arias D, Fuertes-Yebra E, Ordonez A, Calzada MJ. Sci Rep. 2020 Jan 24;10(1):1175. doi: 10.1038/s41598-020-58137-w. PubMed
TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains. Kaiho-Soma A, Akizuki Y, Igarashi K, Endo A, Shoda T, Kawase Y, Demizu Y, Naito M, Saeki Y, Tanaka K, Ohtake F. Mol Cell. 2021 Apr 1;81(7):1411-1424.e7. doi: 10.1016/j.molcel.2021.01.023. Epub 2021 Feb 9. PubMed
MIG-6 is essential for promoting glucose metabolic reprogramming and tumor growth in triple-negative breast cancer. He J, Li CF, Lee HJ, Shin DH, Chern YJ, Pereira De Carvalho B, Chan CH. EMBO Rep. 2021 May 5;22(5):e50781. doi: 10.15252/embr.202050781. Epub 2021 Mar 3. PubMed
Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Teng KW, Tsai ST, Hattori T, Fedele C, Koide A, Yang C, Hou X, Zhang Y, Neel BG, O'Bryan JP, Koide S. Nat Commun. 2021 May 11;12(1):2656. doi: 10.1038/s41467-021-22969-5. PubMed
Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity. Lv D, Pal P, Liu X, Jia Y, Thummuri D, Zhang P, Hu W, Pei J, Zhang Q, Zhou S, Khan S, Zhang X, Hua N, Yang Q, Arango S, Zhang W, Nayak D, Olsen SK, Weintraub ST, Hromas R, Konopleva M, Yuan Y, Zheng G, Zhou D. Nat Commun. 2021 Nov 25;12(1):6896. doi: 10.1038/s41467-021-27210-x. PubMed
pVHL-mediated SMAD3 degradation suppresses TGF-beta signaling. Zhou J, Dabiri Y, Gama-Brambila RA, Ghafoory S, Altinbay M, Mehrabi A, Golriz M, Blagojevic B, Reuter S, Han K, Seidel A, Dikic I, Wolfl S, Cheng X. J Cell Biol. 2022 Jan 3;221(1):e202012097. doi: 10.1083/jcb.202012097. Epub 2021 Dec 3. PubMed

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