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pcDNA3-FLAG-Rheb-N153T Citations (10)

Originally described in: Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells.
Urano J, Sato T, Matsuo T, Otsubo Y, Yamamoto M, Tamanoi F Proc Natl Acad Sci U S A. 2007 Feb 27. 104(9):3514-9.
PubMed Journal

Articles Citing pcDNA3-FLAG-Rheb-N153T

Articles
Glutaminolysis activates Rag-mTORC1 signaling. Duran RV, Oppliger W, Robitaille AM, Heiserich L, Skendaj R, Gottlieb E, Hall MN. Mol Cell. 2012 Aug 10;47(3):349-58. doi: 10.1016/j.molcel.2012.05.043. Epub 2012 Jun 29. PubMed
HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Duran RV, MacKenzie ED, Boulahbel H, Frezza C, Heiserich L, Tardito S, Bussolati O, Rocha S, Hall MN, Gottlieb E. Oncogene. 2013 Sep 19;32(38):4549-56. doi: 10.1038/onc.2012.465. Epub 2012 Oct 22. PubMed
TGF-beta/Smad3 activates mammalian target of rapamycin complex-1 to promote collagen production by increasing HIF-1alpha expression. Rozen-Zvi B, Hayashida T, Hubchak SC, Hanna C, Platanias LC, Schnaper HW. Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F485-94. doi: 10.1152/ajprenal.00215.2013. Epub 2013 Jun 12. PubMed
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. Carroll B, Maetzel D, Maddocks OD, Otten G, Ratcliff M, Smith GR, Dunlop EA, Passos JF, Davies OR, Jaenisch R, Tee AR, Sarkar S, Korolchuk VI. Elife. 2016 Jan 7;5. pii: e11058. doi: 10.7554/eLife.11058. PubMed
Mitochondria are required for pro-ageing features of the senescent phenotype. Correia-Melo C, Marques FD, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SW, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4. PubMed
Regulation of mTORC1 by lysosomal calcium and calmodulin. Li RJ, Xu J, Fu C, Zhang J, Zheng YG, Jia H, Liu JO. Elife. 2016 Oct 27;5. pii: e19360. doi: 10.7554/eLife.19360. PubMed
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR. Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV. Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009. Epub 2018 May 31. PubMed

Associated Plasmids

The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1. Demian WL, Persaud A, Jiang C, Coyaud E, Liu S, Kapus A, Kafri R, Raught B, Rotin D. Cell Rep. 2019 May 7;27(6):1886-1896.e6. doi: 10.1016/j.celrep.2019.04.034. PubMed
Restriction of intracellular Salmonella replication by restoring TFEB-mediated xenophagy. Ammanathan V, Mishra P, Chavalmane AK, Muthusamy S, Jadhav V, Siddamadappa C, Manjithaya R. Autophagy. 2019 Nov 19:1-14. doi: 10.1080/15548627.2019.1689770. PubMed
Na(+)/H(+)-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells. Gong YY, Shao H, Li Y, Brafford P, Stine ZE, Sun J, Felsher DW, Orange JS, Albelda SM, Dang CV. Cancer Res Commun. 2022 Aug;2(8):842-856. doi: 10.1158/2767-9764.crc-22-0270. Epub 2022 Aug 22. PubMed

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