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pLKO.1.sh.beta-catenin.2279 Citations (8)

Originally described in: CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.
Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC Nature. 2008 Sep 25. 455(7212):547-51.
PubMed Journal

Articles Citing pLKO.1.sh.beta-catenin.2279

Articles
The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Pai P, Rachagani S, Lakshmanan I, Macha MA, Sheinin Y, Smith LM, Ponnusamy MP, Batra SK. Mol Oncol. 2016 Feb;10(2):224-39. doi: 10.1016/j.molonc.2015.10.005. Epub 2015 Oct 19. PubMed
Axitinib blocks Wnt/beta-catenin signaling and directs asymmetric cell division in cancer. Qu Y, Gharbi N, Yuan X, Olsen JR, Blicher P, Dalhus B, Brokstad KA, Lin B, Oyan AM, Zhang W, Kalland KH, Ke X. Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9339-44. doi: 10.1073/pnas.1604520113. Epub 2016 Aug 1. PubMed
Adipose- and muscle-derived Wnts trigger pancreatic beta-cell adaptation to systemic insulin resistance. Kozinski K, Jazurek M, Dobrzyn P, Janikiewicz J, Kolczynska K, Gajda A, Dobrzyn A. Sci Rep. 2016 Aug 16;6:31553. doi: 10.1038/srep31553. PubMed
A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Huang T, Alvarez AA, Pangeni RP, M Horbinski C, Lu S, Kim SH, James CD, J Raizer J, A Kessler J, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY. Nat Commun. 2016 Oct 4;7:12885. doi: 10.1038/ncomms12885. PubMed
beta-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q). Li L, Sheng Y, Li W, Hu C, Mittal N, Tohyama K, Seba A, Zhao YY, Ozer H, Zhu T, Qian Z. Cancer Res. 2017 Jun 13. doi: 10.1158/0008-5472.CAN-17-0202. PubMed
R-Spondin1/LGR5 Activates TGFbeta Signaling and Suppresses Colon Cancer Metastasis. Zhou X, Geng L, Wang D, Yi H, Talmon G, Wang J. Cancer Res. 2017 Dec 1;77(23):6589-6602. doi: 10.1158/0008-5472.CAN-17-0219. Epub 2017 Sep 22. PubMed
Trefoil factor 3 promotes pancreatic carcinoma progression via WNT pathway activation mediated by enhanced WNT ligand expression. Cheng F, Wang X, Chiou YS, He C, Guo H, Tan YQ, Basappa B, Zhu T, Pandey V, Lobie PE. Cell Death Dis. 2022 Mar 25;13(3):265. doi: 10.1038/s41419-022-04700-4. PubMed
Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-beta-catenin pathway activation in Ewing sarcoma. Shirai R, Biebighauser T, Walker D, Oviedo J, Nelson-Taylor S, Bodlak A, Porfilio T, Oike N, Goodspeed A, Hayashi M. PLoS One. 2024 Jun 14;19(6):e0305490. doi: 10.1371/journal.pone.0305490. eCollection 2024. PubMed

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