pLKO.1.sh.beta-catenin.1248 Citations (13)

Originally described in: CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.
Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC Nature. 2008 Sep 25. 455(7212):547-51. PubMed Journal

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Articles Citing pLKO.1.sh.beta-catenin.1248

Articles
Physiological beta-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma. Cheng Y, Cheung AK, Ko JM, Phoon YP, Chiu PM, Lo PH, Waterman ML, Lung ML. BMC Cell Biol. 2013 Sep 27;14:44. doi: 10.1186/1471-2121-14-44. PubMed
The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Pai P, Rachagani S, Lakshmanan I, Macha MA, Sheinin Y, Smith LM, Ponnusamy MP, Batra SK. Mol Oncol. 2016 Feb;10(2):224-39. doi: 10.1016/j.molonc.2015.10.005. Epub 2015 Oct 19. PubMed
Axitinib blocks Wnt/beta-catenin signaling and directs asymmetric cell division in cancer. Qu Y, Gharbi N, Yuan X, Olsen JR, Blicher P, Dalhus B, Brokstad KA, Lin B, Oyan AM, Zhang W, Kalland KH, Ke X. Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9339-44. doi: 10.1073/pnas.1604520113. Epub 2016 Aug 1. PubMed
MUC4 is negatively regulated through the Wnt/beta-catenin pathway via the Notch effector Hath1 in colorectal cancer. Pai P, Rachagani S, Dhawan P, Sheinin YM, Macha MA, Qazi AK, Chugh S, Ponnusamy MP, Mallya K, Pothuraju R, Batra SK. Genes Cancer. 2016 May;7(5-6):154-68. doi: 10.18632/genesandcancer.108. PubMed
A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Huang T, Alvarez AA, Pangeni RP, M Horbinski C, Lu S, Kim SH, James CD, J Raizer J, A Kessler J, Brenann CW, Sulman EP, Finocchiaro G, Tan M, Nishikawa R, Lu X, Nakano I, Hu B, Cheng SY. Nat Commun. 2016 Oct 4;7:12885. doi: 10.1038/ncomms12885. PubMed
beta-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q). Li L, Sheng Y, Li W, Hu C, Mittal N, Tohyama K, Seba A, Zhao YY, Ozer H, Zhu T, Qian Z. Cancer Res. 2017 Jun 13. doi: 10.1158/0008-5472.CAN-17-0202. PubMed
R-Spondin1/LGR5 Activates TGFbeta Signaling and Suppresses Colon Cancer Metastasis. Zhou X, Geng L, Wang D, Yi H, Talmon G, Wang J. Cancer Res. 2017 Dec 1;77(23):6589-6602. doi: 10.1158/0008-5472.CAN-17-0219. Epub 2017 Sep 22. PubMed
Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells. Kim JY, Lee JS, Hwang HS, Lee DR, Park CY, Jung SJ, You YR, Kim DS, Kim DW. Exp Mol Med. 2018 Apr 13;50(4):24. doi: 10.1038/s12276-018-0044-y. PubMed
beta-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors. You C, Zhang S, Sun Y, Zhang S, Tang G, Tang F, Liu X, Xiao Y, Zhang J, Gong Y, Xie C. Int J Oncol. 2018 Nov;53(5):2258-2268. doi: 10.3892/ijo.2018.4529. Epub 2018 Aug 21. PubMed
Promotion of epithelial-mesenchymal transformation by hepatocellular carcinoma-educated macrophages through Wnt2b/beta-catenin/c-Myc signaling and reprogramming glycolysis. Jiang Y, Han Q, Zhao H, Zhang J. J Exp Clin Cancer Res. 2021 Jan 6;40(1):13. doi: 10.1186/s13046-020-01808-3. PubMed
Pannexin 1 binds beta-catenin to modulate melanoma cell growth and metabolism. Sayedyahossein S, Huang K, Li Z, Zhang C, Kozlov AM, Johnston D, Nouri-Nejad D, Dagnino L, Betts DH, Sacks DB, Penuela S. J Biol Chem. 2021 Jan-Jun;296:100478. doi: 10.1016/j.jbc.2021.100478. Epub 2021 Feb 26. PubMed
Trefoil factor 3 promotes pancreatic carcinoma progression via WNT pathway activation mediated by enhanced WNT ligand expression. Cheng F, Wang X, Chiou YS, He C, Guo H, Tan YQ, Basappa B, Zhu T, Pandey V, Lobie PE. Cell Death Dis. 2022 Mar 25;13(3):265. doi: 10.1038/s41419-022-04700-4. PubMed
Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-beta-catenin pathway activation in Ewing sarcoma. Shirai R, Biebighauser T, Walker D, Oviedo J, Nelson-Taylor S, Bodlak A, Porfilio T, Oike N, Goodspeed A, Hayashi M. PLoS One. 2024 Jun 14;19(6):e0305490. doi: 10.1371/journal.pone.0305490. eCollection 2024. PubMed

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