pRK5-HA GST RagC wt Citations (11)
Originally described in: The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM Science. 2008 Jun 13. 320(5882):1496-501. PubMed Journal
Articles Citing pRK5-HA GST RagC wt
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| Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Kim JS, Ro SH, Kim M, Park HW, Semple IA, Park H, Cho US, Wang W, Guan KL, Karin M, Lee JH. Sci Rep. 2015 Mar 30;5:9502. doi: 10.1038/srep09502. PubMed |
| PRL-3 activates mTORC1 in Cancer Progression. Ye Z, Al-Aidaroos AQ, Park JE, Yuen HF, Zhang SD, Gupta A, Lin Y, Shen HM, Zeng Q. Sci Rep. 2015 Nov 24;5:17046. doi: 10.1038/srep17046. PubMed |
| The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice. Khayati K, Antikainen H, Bonder EM, Weber GF, Kruger WD, Jakubowski H, Dobrowolski R. FASEB J. 2017 Feb;31(2):598-609. doi: 10.1096/fj.201600915R. Epub 2016 Oct 25. PubMed |
| TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer. Cooper JM, Ou YH, McMillan EA, Vaden RM, Zaman A, Bodemann BO, Makkar G, Posner BA, White MA. Cancer Res. 2017 Sep 15;77(18):5077-5094. doi: 10.1158/0008-5472.CAN-17-0829. Epub 2017 Jul 17. PubMed |
Galectins Control mTOR in Response to Endomembrane Damage.
Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V.
Mol Cell. 2018 Apr 5;70(1):120-135.e8. doi: 10.1016/j.molcel.2018.03.009.
PubMed
Associated Plasmids |
| Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction. Pal R, Palmieri M, Chaudhury A, Klisch TJ, di Ronza A, Neilson JR, Rodney GG, Sardiello M. Nat Commun. 2018 Oct 19;9(1):4351. doi: 10.1038/s41467-018-06844-4. PubMed |
| Cancer-secreted miRNAs regulate amino-acid-induced mTORC1 signaling and fibroblast protein synthesis. Fong MY, Yan W, Ghassemian M, Wu X, Zhou X, Cao M, Jiang L, Wang J, Liu X, Zhang J, Wang SE. EMBO Rep. 2021 Feb 3;22(2):e51239. doi: 10.15252/embr.202051239. Epub 2020 Dec 20. PubMed |
| ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway. Wrobel M, Cendrowski J, Szymanska E, Grebowicz-Maciukiewicz M, Budick-Harmelin N, Macias M, Szybinska A, Mazur M, Kolmus K, Goryca K, Dabrowska M, Paziewska A, Mikula M, Miaczynska M. Life Sci Alliance. 2022 Mar 30;5(7). pii: 5/7/e202101239. doi: 10.26508/lsa.202101239. Print 2022 Jul. PubMed |
| Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy-lysosomal pathway. Du X, Di Malta C, Fang Z, Shen T, Niu X, Chen M, Jin B, Yu H, Lei L, Gao W, Song Y, Wang Z, Xu C, Cao Z, Liu G, Li X. Acta Pharm Sin B. 2022 Jun;12(6):2869-2886. doi: 10.1016/j.apsb.2021.12.012. Epub 2021 Dec 22. PubMed |
| Cytoskeletal vimentin regulates cell size and autophagy through mTORC1 signaling. Mohanasundaram P, Coelho-Rato LS, Modi MK, Urbanska M, Lautenschlager F, Cheng F, Eriksson JE. PLoS Biol. 2022 Sep 13;20(9):e3001737. doi: 10.1371/journal.pbio.3001737. eCollection 2022 Sep. PubMed |
| Dosage sensitivity to Pumilio1 variants in the mouse brain reflects distinct molecular mechanisms. Botta S, de Prisco N, Chemiakine A, Brandt V, Cabaj M, Patel P, Doron-Mandel E, Treadway CJ, Jovanovic M, Brown NG, Soni RK, Gennarino VA. EMBO J. 2023 Jun 1;42(11):e112721. doi: 10.15252/embj.2022112721. Epub 2023 Apr 18. PubMed |
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