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pRK5-HA GST RagB 99L Citations (17)

Originally described in: The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM Science. 2008 Jun 13. 320(5882):1496-501.
PubMed Journal

Articles Citing pRK5-HA GST RagB 99L

Articles
A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1. Cully M, Genevet A, Warne P, Treins C, Liu T, Bastien J, Baum B, Tapon N, Leevers SJ, Downward J. Mol Cell Biol. 2010 Jan;30(2):481-95. doi: 10.1128/MCB.00688-09. Epub 2009 Nov 16. PubMed
Glutaminolysis activates Rag-mTORC1 signaling. Duran RV, Oppliger W, Robitaille AM, Heiserich L, Skendaj R, Gottlieb E, Hall MN. Mol Cell. 2012 Aug 10;47(3):349-58. doi: 10.1016/j.molcel.2012.05.043. Epub 2012 Jun 29. PubMed
HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Duran RV, MacKenzie ED, Boulahbel H, Frezza C, Heiserich L, Tardito S, Bussolati O, Rocha S, Hall MN, Gottlieb E. Oncogene. 2013 Sep 19;32(38):4549-56. doi: 10.1038/onc.2012.465. Epub 2012 Oct 22. PubMed
Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes. Martina JA, Puertollano R. J Cell Biol. 2013 Feb 18;200(4):475-91. doi: 10.1083/jcb.201209135. Epub 2013 Feb 11. PubMed
Characteristics and requirements of basal autophagy in HEK 293 cells. Musiwaro P, Smith M, Manifava M, Walker SA, Ktistakis NT. Autophagy. 2013 Sep;9(9):1407-17. doi: 10.4161/auto.25455. Epub 2013 Jun 20. PubMed
The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris. Martina JA, Diab HI, Lishu L, Jeong-A L, Patange S, Raben N, Puertollano R. Sci Signal. 2014 Jan 21;7(309):ra9. doi: 10.1126/scisignal.2004754. PubMed
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. Carroll B, Maetzel D, Maddocks OD, Otten G, Ratcliff M, Smith GR, Dunlop EA, Passos JF, Davies OR, Jaenisch R, Tee AR, Sarkar S, Korolchuk VI. Elife. 2016 Jan 7;5. pii: e11058. doi: 10.7554/eLife.11058. PubMed
The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue. Wada S, Neinast M, Jang C, Ibrahim YH, Lee G, Babu A, Li J, Hoshino A, Rowe GC, Rhee J, Martina JA, Puertollano R, Blenis J, Morley M, Baur JA, Seale P, Arany Z. Genes Dev. 2016 Nov 15;30(22):2551-2564. Epub 2016 Dec 2. PubMed
Dynamin-dependent amino acid endocytosis activates mechanistic target of rapamycin complex 1 (mTORC1). Shibutani S, Okazaki H, Iwata H. J Biol Chem. 2017 Nov 3;292(44):18052-18061. doi: 10.1074/jbc.M117.776443. Epub 2017 Aug 14. PubMed
Galectins Control mTOR in Response to Endomembrane Damage. Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V. Mol Cell. 2018 Apr 5;70(1):120-135.e8. doi: 10.1016/j.molcel.2018.03.009. PubMed

Associated Plasmids

The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage. Jeong E, Brady OA, Martina JA, Pirooznia M, Tunc I, Puertollano R. Elife. 2018 Dec 6;7. pii: 40856. doi: 10.7554/eLife.40856. PubMed
Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression. Ericksen RE, Lim SL, McDonnell E, Shuen WH, Vadiveloo M, White PJ, Ding Z, Kwok R, Lee P, Radda GK, Toh HC, Hirschey MD, Han W. Cell Metab. 2019 May 7;29(5):1151-1165.e6. doi: 10.1016/j.cmet.2018.12.020. Epub 2019 Jan 17. PubMed
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Huang X, Gan G, Wang X, Xu T, Xie W. Autophagy. 2019 Jul;15(7):1258-1279. doi: 10.1080/15548627.2019.1580105. Epub 2019 Feb 20. PubMed
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis. Odle RI, Walker SA, Oxley D, Kidger AM, Balmanno K, Gilley R, Okkenhaug H, Florey O, Ktistakis NT, Cook SJ. Mol Cell. 2020 Jan 16;77(2):228-240.e7. doi: 10.1016/j.molcel.2019.10.016. Epub 2019 Nov 13. PubMed
Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex. Hirst J, Hesketh GG, Gingras AC, Robinson MS. J Cell Biol. 2021 Feb 1;220(2). pii: 211690. doi: 10.1083/jcb.202002075. PubMed
Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis. Bodineau C, Tome M, Courtois S, Costa ASH, Sciacovelli M, Rousseau B, Richard E, Vacher P, Parejo-Perez C, Bessede E, Varon C, Soubeyran P, Frezza C, Murdoch PDS, Villar VH, Duran RV. Nat Commun. 2021 Aug 10;12(1):4814. doi: 10.1038/s41467-021-25079-4. PubMed
Cytoskeletal vimentin regulates cell size and autophagy through mTORC1 signaling. Mohanasundaram P, Coelho-Rato LS, Modi MK, Urbanska M, Lautenschlager F, Cheng F, Eriksson JE. PLoS Biol. 2022 Sep 13;20(9):e3001737. doi: 10.1371/journal.pbio.3001737. eCollection 2022 Sep. PubMed

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