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pRK5-HA GST RagA wt Citations (4)

Originally described in: The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
Sancak Y, Peterson TR, Shaul YD, Lindquist RA, Thoreen CC, Bar-Peled L, Sabatini DM Science. 2008 Jun 13. 320(5882):1496-501.
PubMed Journal

Articles Citing pRK5-HA GST RagA wt

Articles
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Rebsamen M, Pochini L, Stasyk T, de Araujo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G. Nature. 2015 Mar 26;519(7544):477-81. doi: 10.1038/nature14107. Epub 2015 Jan 7. PubMed
TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer. Cooper JM, Ou YH, McMillan EA, Vaden RM, Zaman A, Bodemann BO, Makkar G, Posner BA, White MA. Cancer Res. 2017 Sep 15;77(18):5077-5094. doi: 10.1158/0008-5472.CAN-17-0829. Epub 2017 Jul 17. PubMed
Galectins Control mTOR in Response to Endomembrane Damage. Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V. Mol Cell. 2018 Apr 5;70(1):120-135.e8. doi: 10.1016/j.molcel.2018.03.009. PubMed

Associated Plasmids

Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction. Pal R, Palmieri M, Chaudhury A, Klisch TJ, di Ronza A, Neilson JR, Rodney GG, Sardiello M. Nat Commun. 2018 Oct 19;9(1):4351. doi: 10.1038/s41467-018-06844-4. PubMed

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