pcDNA3-S33Y Beta-catenin Citations (44)
Originally described in: Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression.Kolligs FT, Hu G, Dang CV, Fearon ER Mol Cell Biol. 1999 Aug . 19(8):5696-706. PubMed
Articles Citing pcDNA3-S33Y Beta-catenin
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| Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells. Schenkel JM, Zloza A, Li W, Narasipura SD, Al-Harthi L. J Immunol. 2010 Aug 15;185(4):2013-9. doi: 10.4049/jimmunol.0902572. Epub 2010 Jul 14. PubMed |
| Rough surface topography enhances the activation of Wnt/beta-catenin signaling in mesenchymal cells. Galli C, Passeri G, Ravanetti F, Elezi E, Pedrazzoni M, Macaluso GM. J Biomed Mater Res A. 2010 Dec 1;95(3):682-90. doi: 10.1002/jbm.a.32887. PubMed |
| Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active beta-catenin. Lavergne E, Hendaoui I, Coulouarn C, Ribault C, Leseur J, Eliat PA, Mebarki S, Corlu A, Clement B, Musso O. Oncogene. 2011 Jan 27;30(4):423-33. doi: 10.1038/onc.2010.432. Epub 2010 Sep 20. PubMed |
| Protein kinase C zeta is a positive modulator of canonical Wnt signaling pathway in tumoral colon cell lines. Luna-Ulloa LB, Hernandez-Maqueda JG, Santoyo-Ramos P, Castaneda-Patlan MC, Robles-Flores M. Carcinogenesis. 2011 Nov;32(11):1615-24. doi: 10.1093/carcin/bgr190. Epub 2011 Aug 22. PubMed |
| beta-Catenin signaling is required for TGF-beta1-induced extracellular matrix production by airway smooth muscle cells. Baarsma HA, Menzen MH, Halayko AJ, Meurs H, Kerstjens HA, Gosens R. Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L956-65. doi: 10.1152/ajplung.00123.2011. Epub 2011 Sep 9. PubMed |
| Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor of growth and beta-catenin activity in colon cancer cells. Hinkel I, Duluc I, Martin E, Guenot D, Freund JN, Gross I. Gastroenterology. 2012 Apr;142(4):875-885.e3. doi: 10.1053/j.gastro.2011.12.037. Epub 2011 Dec 24. PubMed |
| Regulation of the DLG tumor suppressor by beta-catenin. Subbaiah VK, Narayan N, Massimi P, Banks L. Int J Cancer. 2012 Nov 15;131(10):2223-33. doi: 10.1002/ijc.27519. Epub 2012 Mar 28. PubMed |
| MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway. Hsieh IS, Chang KC, Tsai YT, Ke JY, Lu PJ, Lee KH, Yeh SD, Hong TM, Chen YL. Carcinogenesis. 2013 Mar;34(3):530-8. doi: 10.1093/carcin/bgs371. Epub 2012 Nov 26. PubMed |
| FOXQ1, a novel target of the Wnt pathway and a new marker for activation of Wnt signaling in solid tumors. Christensen J, Bentz S, Sengstag T, Shastri VP, Anderle P. PLoS One. 2013;8(3):e60051. doi: 10.1371/journal.pone.0060051. Epub 2013 Mar 26. PubMed |
| Low-dose gamma-radiation inhibits IL-1beta-induced dedifferentiation and inflammation of articular chondrocytes via blockage of catenin signaling. Hong EH, Song JY, Lee SJ, Park IC, Um HD, Park JK, Lee KH, Nam SY, Hwang SG. IUBMB Life. 2014 Feb;66(2):128-37. doi: 10.1002/iub.1248. Epub 2014 Mar 6. PubMed |
| Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia. Ng OH, Erbilgin Y, Firtina S, Celkan T, Karakas Z, Aydogan G, Turkkan E, Yildirmak Y, Timur C, Zengin E, van Dongen JJ, Staal FJ, Ozbek U, Sayitoglu M. Blood Cancer J. 2014 Mar 14;4:e192. doi: 10.1038/bcj.2014.12. PubMed |
| Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model. Bhardwaj A, Singh S, Srivastava SK, Arora S, Hyde SJ, Andrews J, Grizzle WE, Singh AP. Br J Cancer. 2014 Apr 15;110(8):2000-10. doi: 10.1038/bjc.2014.141. Epub 2014 Mar 18. PubMed |
| TGF-beta-activated kinase 1 (TAK1) signaling regulates TGF-beta-induced WNT-5A expression in airway smooth muscle cells via Sp1 and beta-catenin. Kumawat K, Menzen MH, Slegtenhorst RM, Halayko AJ, Schmidt M, Gosens R. PLoS One. 2014 Apr 11;9(4):e94801. doi: 10.1371/journal.pone.0094801. eCollection 2014. PubMed |
| Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/beta-catenin signaling pathway. Fu Y, Chang H, Peng X, Bai Q, Yi L, Zhou Y, Zhu J, Mi M. PLoS One. 2014 Jul 28;9(7):e102535. doi: 10.1371/journal.pone.0102535. eCollection 2014. PubMed |
| Endostar, a modified recombinant human endostatin, suppresses angiogenesis through inhibition of Wnt/beta-catenin signaling pathway. Xu X, Mao W, Chen Q, Zhuang Q, Wang L, Dai J, Wang H, Huang Z. PLoS One. 2014 Sep 18;9(9):e107463. doi: 10.1371/journal.pone.0107463. eCollection 2014. PubMed |
| Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via beta-catenin stabilization. Jansen SR, Holman R, Hedemann I, Frankes E, Elzinga CR, Timens W, Gosens R, de Bont ES, Schmidt M. J Cell Mol Med. 2015 Jan;19(1):210-26. doi: 10.1111/jcmm.12418. Epub 2014 Sep 30. PubMed |
| beta-catenin mediates stress resilience through Dicer1/microRNA regulation. Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonte B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Pena C, Calipari ES, Koo JW, Mouzon E, Ghose S, Tamminga C, Neve R, Shen L, Nestler EJ. Nature. 2014 Dec 4;516(7529):51-5. doi: 10.1038/nature13976. Epub 2014 Nov 12. PubMed |
| A Regulatory Network Involving beta-Catenin, e-Cadherin, PI3k/Akt, and Slug Balances Self-Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling. Huang TS, Li L, Moalim-Nour L, Jia D, Bai J, Yao Z, Bennett SA, Figeys D, Wang L. Stem Cells. 2015 May;33(5):1419-33. doi: 10.1002/stem.1944. PubMed |
| beta-catenin SUMOylation is involved in the dysregulated proliferation of myeloma cells. Huang HJ, Zhou LL, Fu WJ, Zhang CY, Jiang H, Du J, Hou J. Am J Cancer Res. 2014 Dec 15;5(1):309-20. eCollection 2015. PubMed |
| Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers. Hnisz D, Schuijers J, Lin CY, Weintraub AS, Abraham BJ, Lee TI, Bradner JE, Young RA. Mol Cell. 2015 Apr 16;58(2):362-70. doi: 10.1016/j.molcel.2015.02.014. Epub 2015 Mar 19. PubMed |
| beta-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis. Cai J, Maitra A, Anders RA, Taketo MM, Pan D. Genes Dev. 2015 Jul 15;29(14):1493-506. doi: 10.1101/gad.264515.115. Epub 2015 Jul 20. PubMed |
| Inhibition of glycogen synthase kinase-3 beta induces apoptosis and mitotic catastrophe by disrupting centrosome regulation in cancer cells. Yoshino Y, Ishioka C. Sci Rep. 2015 Aug 21;5:13249. doi: 10.1038/srep13249. PubMed |
| beta-Catenin signaling positively regulates glutamate uptake and metabolism in astrocytes. Lutgen V, Narasipura SD, Sharma A, Min S, Al-Harthi L. J Neuroinflammation. 2016 Sep 10;13(1):242. doi: 10.1186/s12974-016-0691-7. PubMed |
| beta-TrCP1 Is a Vacillatory Regulator of Wnt Signaling. Long MJ, Lin HY, Parvez S, Zhao Y, Poganik JR, Huang P, Aye Y. Cell Chem Biol. 2017 Aug 17;24(8):944-957.e7. doi: 10.1016/j.chembiol.2017.06.009. Epub 2017 Jul 20. PubMed |
| Wnt/beta-Catenin Signaling Induces Integrin alpha4beta1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice. Sorcini D, Bruscoli S, Frammartino T, Cimino M, Mazzon E, Galuppo M, Bramanti P, Al-Banchaabouchi M, Farley D, Ermakova O, Britanova O, Izraelson M, Chudakov D, Biagioli M, Sportoletti P, Flamini S, Raspa M, Scavizzi F, Nerlov C, Migliorati G, Riccardi C, Bereshchenko O. J Immunol. 2017 Nov 1;199(9):3031-3041. doi: 10.4049/jimmunol.1700247. Epub 2017 Sep 22. PubMed |
| beta-Catenin Directs Nuclear Factor-kappaB p65 Output via CREB-Binding Protein/p300 in Human Airway Smooth Muscle. Koopmans T, Eilers R, Menzen M, Halayko A, Gosens R. Front Immunol. 2017 Sep 8;8:1086. doi: 10.3389/fimmu.2017.01086. eCollection 2017. PubMed |
| APC downregulated 1 inhibits breast cancer cell invasion by inhibiting the canonical WNT signaling pathway. Cho SG. Oncol Lett. 2017 Oct;14(4):4845-4852. doi: 10.3892/ol.2017.6801. Epub 2017 Aug 23. PubMed |
| Knockdown of aquaporin-5 sensitizes colorectal cancer cells to 5-fluorouracil via inhibition of the Wnt-beta-catenin signaling pathway. Li Q, Yang T, Li D, Ding F, Bai G, Wang W, Sun H. Biochem Cell Biol. 2018 Oct;96(5):572-579. doi: 10.1139/bcb-2017-0162. Epub 2018 Feb 1. PubMed |
| Knockdown of the prolyl isomerase Pin1 inhibits Hep-2 cell growth, migration, and invasion by targeting the beta-catenin signaling pathway. Fan G, Wang L, Xu J, Jiang P, Wang W, Huang Y, Lv M, Liu S. Biochem Cell Biol. 2018 May 16:1-8. doi: 10.1139/bcb-2017-0334. PubMed |
| beta-Catenin expression is associated with cell invasiveness in pancreatic cancer. Nan JN, Kim OR, Lee MA. Korean J Intern Med. 2018 Oct 26. pii: kjim.2017.155. doi: 10.3904/kjim.2017.155. PubMed |
| Molecular characterization of Wnt pathway and function of beta-catenin overexpression in medulloblastoma cell lines. Geron L, Salomao KB, Borges KS, Andrade AF, Correa CAP, Scrideli CA, Tone LG. Cytotechnology. 2018 Dec;70(6):1713-1722. doi: 10.1007/s10616-018-0260-2. Epub 2018 Oct 29. PubMed |
| FOXC1 silencing inhibits the epithelialtomesenchymal transition of glioma cells: Involvement of betacatenin signaling. Cao Q, Wang X, Shi Y, Zhang M, Yang J, Dong M, Mi Y, Zhang Z, Liu K, Jiang L, Wang N, Wang P. Mol Med Rep. 2019 Jan;19(1):251-261. doi: 10.3892/mmr.2018.9650. Epub 2018 Nov 13. PubMed |
| Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling. Papadakos KS, Bartoschek M, Rodriguez C, Gialeli C, Jin SB, Lendahl U, Pietras K, Blom AM. Matrix Biol. 2018 Nov 28. pii: S0945-053X(18)30391-3. doi: 10.1016/j.matbio.2018.11.007. PubMed |
| Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting beta-catenin activity. Huang X, Xue H, Ma J, Zhang Y, Zhang J, Liu Y, Qin X, Sun C. J Cell Mol Med. 2019 Jun;23(6):4443-4453. doi: 10.1111/jcmm.14340. Epub 2019 Apr 16. PubMed |
| Silencing LGR6 Attenuates Stemness and Chemoresistance via Inhibiting Wnt/beta-Catenin Signaling in Ovarian Cancer. Ruan X, Liu A, Zhong M, Wei J, Zhang W, Rong Y, Liu W, Li M, Qing X, Chen G, Li R, Liao Y, Liu Q, Zhang X, Ren D, Wang Y. Mol Ther Oncolytics. 2019 Apr 19;14:94-106. doi: 10.1016/j.omto.2019.04.002. eCollection 2019 Sep 27. PubMed |
| beta-Catenin stabilization in NOD dendritic cells increases IL-12 production and subsequent induction of IFN-gamma-producing T cells. Zirnheld AL, Villard M, Harrison AM, Kosiewicz MM, Alard P. J Leukoc Biol. 2019 Dec;106(6):1349-1358. doi: 10.1002/JLB.3A0919-244R. Epub 2019 Sep 30. PubMed |
| beta-Catenin Preserves the Stem State of Murine Bone Marrow Stromal Cells Through Activation of EZH2. Sen B, Paradise CR, Xie Z, Sankaran J, Uzer G, Styner M, Meyer M, Dudakovic A, van Wijnen AJ, Rubin J. J Bone Miner Res. 2020 Jun;35(6):1149-1162. doi: 10.1002/jbmr.3975. Epub 2020 Feb 24. PubMed |
| Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling. Nouri P, Gotz S, Rauser B, Irmler M, Peng C, Trumbach D, Kempny C, Lechermeier CG, Bryniok A, Dlugos A, Euchner E, Beckers J, Brodski C, Klumper C, Wurst W, Prakash N. Front Cell Dev Biol. 2020 Oct 26;8:587778. doi: 10.3389/fcell.2020.587778. eCollection 2020. PubMed |
| Activation of Wnt/beta-catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS-1. Tian S, Tan S, Jia W, Zhao J, Sun X. J Neurochem. 2021 May;157(3):467-478. doi: 10.1111/jnc.15277. Epub 2020 Dec 31. PubMed |
| Pyrvinium Treatment Confers Hepatic Metabolic Benefits via beta-Catenin Downregulation and AMPK Activation. Zhou S, Obianom ON, Huang J, Guo D, Yang H, Li Q, Shu Y. Pharmaceutics. 2021 Mar 4;13(3). pii: pharmaceutics13030330. doi: 10.3390/pharmaceutics13030330. PubMed |
| PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of beta-catenin and PD-L1. Ma Y, Xia P, Wang Z, Xu J, Zhang L, Jiang Y. Neoplasia. 2021 Sep;23(9):912-928. doi: 10.1016/j.neo.2021.07.004. Epub 2021 Jul 26. PubMed |
| Heparanase-Induced Activation of AKT Stabilizes beta-Catenin and Modulates Wnt/beta-Catenin Signaling during Herpes Simplex Virus 1 Infection. Koujah L, Madavaraju K, Agelidis AM, Patil CD, Shukla D. mBio. 2021 Dec 21;12(6):e0279221. doi: 10.1128/mBio.02792-21. Epub 2021 Nov 9. PubMed |
| The oncogenic transcription factor FOXQ1 is a differential regulator of Wnt target genes. Pizzolato G, Moparthi L, Soderholm S, Cantu C, Koch S. J Cell Sci. 2022 Oct 1;135(19):jcs260082. doi: 10.1242/jcs.260082. Epub 2022 Oct 10. PubMed |
| Stromal cartilage oligomeric matrix protein as a tumorigenic driver in ovarian cancer via Notch3 signaling and epithelial-to-mesenchymal transition. Gorji-Bahri G, Krishna BM, Hagerling C, Orimo A, Jirstrom K, Papadakos KS, Blom AM. J Transl Med. 2024 Apr 13;22(1):351. doi: 10.1186/s12967-024-05083-0. PubMed |
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