pLenti PGK Hygro DEST (w530-1) Citations (19)
Originally described in: A versatile viral system for expression and depletion of proteins in mammalian cells.Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD. PLoS One. 2009 Aug 6;4(8):e6529. PubMed Journal
Articles Citing pLenti PGK Hygro DEST (w530-1)
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Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells. Verbeke S, Richard E, Monceau E, Schmidt X, Rousseau B, Velasco V, Bernard D, Bonnefoi H, MacGrogan G, Iggo RD. Breast Cancer Res. 2014 Dec 20;16(6):504. doi: 10.1186/s13058-014-0504-9. PubMed |
Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. Bailey ML, Singh T, Mero P, Moffat J, Hieter P. Genetics. 2015 Nov;201(3):885-95. doi: 10.1534/genetics.115.180653. Epub 2015 Sep 8. PubMed |
Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations. Vaz M, Hwang SY, Kagiampakis I, Phallen J, Patil A, O'Hagan HM, Murphy L, Zahnow CA, Gabrielson E, Velculescu VE, Easwaran HP, Baylin SB. Cancer Cell. 2017 Sep 11;32(3):360-376.e6. doi: 10.1016/j.ccell.2017.08.006. PubMed |
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA. Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermuller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V. Nat Commun. 2018 Jan 19;9(1):299. doi: 10.1038/s41467-017-02582-1. PubMed |
Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates. Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Elife. 2018 May 10;7. pii: 36620. doi: 10.7554/eLife.36620. PubMed |
hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability. Li Z, Liu B, Jin W, Wu X, Zhou M, Liu VZ, Goel A, Shen Z, Zheng L, Shen B. EMBO J. 2018 Jul 13;37(14). pii: embj.201796729. doi: 10.15252/embj.201796729. Epub 2018 May 17. PubMed |
PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition. McNeill RS, Stroobant EE, Smithberger E, Canoutas DA, Butler MK, Shelton AK, Patel SD, Limas JC, Skinner KR, Bash RE, Schmid RS, Miller CR. PLoS One. 2018 Jul 5;13(7):e0200014. doi: 10.1371/journal.pone.0200014. eCollection 2018. PubMed |
Chemically induced vesiculation as a platform for studying TMEM16F activity. Han TW, Ye W, Bethel NP, Zubia M, Kim A, Li KH, Burlingame AL, Grabe M, Jan YN, Jan LY. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1309-1318. doi: 10.1073/pnas.1817498116. Epub 2019 Jan 8. PubMed |
Development of a Synthetic 3-ketosteroid Delta(1)-dehydrogenase for the Generation of a Novel Catabolic Pathway Enabling Cholesterol Degradation in Human Cells. D'Arcy BM, Swingle MR, Schambeau L, Pannell L, Prakash A, Honkanen RE. Sci Rep. 2019 Apr 12;9(1):5969. doi: 10.1038/s41598-019-42046-8. PubMed |
Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells. Delfarah A, Parrish S, Junge JA, Yang J, Seo F, Li S, Mac J, Wang P, Fraser SE, Graham NA. J Biol Chem. 2019 Jul 5;294(27):10564-10578. doi: 10.1074/jbc.RA118.005806. Epub 2019 May 28. PubMed |
Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters. Petkau N, Budak H, Zhou X, Oster H, Eichele G. Elife. 2019 Jul 11;8. pii: 43235. doi: 10.7554/eLife.43235. PubMed |
Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. Han T, Jiang S, Zheng H, Yin Q, Xie M, Little MR, Yin X, Chen M, Song SJ, Beg AA, Pandolfi PP, Wan L. Nat Commun. 2019 Aug 16;10(1):3716. doi: 10.1038/s41467-019-11618-7. PubMed |
PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia. Radzisheuskaya A, Shliaha PV, Grinev V, Lorenzini E, Kovalchuk S, Shlyueva D, Gorshkov V, Hendrickson RC, Jensen ON, Helin K. Nat Struct Mol Biol. 2019 Nov;26(11):999-1012. doi: 10.1038/s41594-019-0313-z. Epub 2019 Oct 14. PubMed |
APOBEC3A is a prominent cytidine deaminase in breast cancer. Cortez LM, Brown AL, Dennis MA, Collins CD, Brown AJ, Mitchell D, Mertz TM, Roberts SA. PLoS Genet. 2019 Dec 16;15(12):e1008545. doi: 10.1371/journal.pgen.1008545. eCollection 2019 Dec. PubMed |
Rational discovery of molecular glue degraders via scalable chemical profiling. Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Muller AC, Zuber J, Geyer M, Thoma NH, Kubicek S, Winter GE. Nat Chem Biol. 2020 Nov;16(11):1199-1207. doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3. PubMed |
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress. Visnes T, Benitez-Buelga C, Cazares-Korner A, Sanjiv K, Hanna BMF, Mortusewicz O, Rajagopal V, Albers JJ, Hagey DW, Bekkhus T, Eshtad S, Baquero JM, Masuyer G, Wallner O, Muller S, Pham T, Gokturk C, Rasti A, Suman S, Torres-Ruiz R, Sarno A, Wiita E, Homan EJ, Karsten S, Marimuthu K, Michel M, Koolmeister T, Scobie M, Loseva O, Almlof I, Unterlass JE, Pettke A, Bostrom J, Pandey M, Gad H, Herr P, Jemth AS, El Andaloussi S, Kalderen C, Rodriguez-Perales S, Benitez J, Krokan HE, Altun M, Stenmark P, Berglund UW, Helleday T. Nucleic Acids Res. 2020 Dec 2;48(21):12234-12251. doi: 10.1093/nar/gkaa1048. PubMed |
Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis. Radzisheuskaya A, Shliaha PV, Grinev VV, Shlyueva D, Damhofer H, Koche R, Gorshkov V, Kovalchuk S, Zhan Y, Rodriguez KL, Johnstone AL, Keogh MC, Hendrickson RC, Jensen ON, Helin K. Mol Cell. 2021 Apr 15;81(8):1749-1765.e8. doi: 10.1016/j.molcel.2021.02.012. Epub 2021 Mar 2. PubMed |
Identification of a Proteomic Signature of Senescence in Primary Human Mammary Epithelial Cells. Delfarah A, Hartel NG, Zheng D, Yang J, Graham NA. J Proteome Res. 2021 Nov 5;20(11):5169-5179. doi: 10.1021/acs.jproteome.1c00659. Epub 2021 Oct 12. PubMed |
Sugar transporter Slc37a2 regulates bone metabolism in mice via a tubular lysosomal network in osteoclasts. Ng PY, Ribet ABP, Guo Q, Mullin BH, Tan JWY, Landao-Bassonga E, Stephens S, Chen K, Yuan J, Abudulai L, Bollen M, Nguyen ETTT, Kular J, Papadimitriou JM, Soe K, Teasdale RD, Xu J, Parton RG, Takayanagi H, Pavlos NJ. Nat Commun. 2023 Feb 21;14(1):906. doi: 10.1038/s41467-023-36484-2. PubMed |
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