HA-HIF2alpha-P405A/P531A-pcDNA3 Citations (21)
Originally described in: The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo.Yan Q, Bartz S, Mao M, Li L, Kaelin WG Mol Cell Biol. 2007 Mar . 27(6):2092-102. PubMed Journal
Articles Citing HA-HIF2alpha-P405A/P531A-pcDNA3
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Astrocyte pVHL and HIF-alpha isoforms are required for embryonic-to-adult vascular transition in the eye. Kurihara T, Westenskow PD, Krohne TU, Aguilar E, Johnson RS, Friedlander M. J Cell Biol. 2011 Nov 14;195(4):689-701. doi: 10.1083/jcb.201107029. PubMed |
The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells. Rider P, Kaplanov I, Romzova M, Bernardis L, Braiman A, Voronov E, Apte RN. Front Immunol. 2012 Sep 14;3:290. doi: 10.3389/fimmu.2012.00290. eCollection 2012. PubMed |
Hypoxia-inducible factor-2alpha and TGF-beta signaling interact to promote normoxic glomerular fibrogenesis. Hanna C, Hubchak SC, Liang X, Rozen-Zvi B, Schumacker PT, Hayashida T, Schnaper HW. Am J Physiol Renal Physiol. 2013 Nov 1;305(9):F1323-31. doi: 10.1152/ajprenal.00155.2013. Epub 2013 Aug 14. PubMed |
Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes. Taniguchi CM, Finger EC, Krieg AJ, Wu C, Diep AN, LaGory EL, Wei K, McGinnis LM, Yuan J, Kuo CJ, Giaccia AJ. Nat Med. 2013 Oct;19(10):1325-30. doi: 10.1038/nm.3294. Epub 2013 Sep 15. PubMed |
Convergence of hypoxia and TGFbeta pathways on cell cycle regulation in human hematopoietic stem/progenitor cells. Wierenga AT, Vellenga E, Schuringa JJ. PLoS One. 2014 Mar 31;9(3):e93494. doi: 10.1371/journal.pone.0093494. eCollection 2014. PubMed |
Hypoxia reduces and redirects selenoprotein biosynthesis. Becker NP, Martitz J, Renko K, Stoedter M, Hybsier S, Cramer T, Schomburg L. Metallomics. 2014 May;6(5):1079-86. doi: 10.1039/c4mt00004h. PubMed |
Hypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP). Evensen NA, Li Y, Kuscu C, Liu J, Cathcart J, Banach A, Zhang Q, Li E, Joshi S, Yang J, Denoya PI, Pastorekova S, Zucker S, Shroyer KR, Cao J. Oncotarget. 2015 Aug 21;6(24):20723-39. PubMed |
Cardioprotective HIF-1alpha-frataxin signaling against ischemia-reperfusion injury. Nanayakkara G, Alasmari A, Mouli S, Eldoumani H, Quindry JC, McGinnis G, Fu X, Berlin A, Peters B, Zhong J, Amin RH. Am J Physiol Heart Circ Physiol. 2015 Jun 12:ajpheart.00875.2014. doi: 10.1152/ajpheart.00875.2014. PubMed |
Class I and IIa HDACs Mediate HIF-1alpha Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1alpha Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc. Schoepflin ZR, Shapiro IM, Risbud MV. J Bone Miner Res. 2016 Jun;31(6):1287-99. doi: 10.1002/jbmr.2787. Epub 2016 Mar 15. PubMed |
Hypoxia-inducible factor-1alpha plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. Kraus RJ, Yu X, Cordes BA, Sathiamoorthi S, Iempridee T, Nawandar DM, Ma S, Romero-Masters JC, McChesney KG, Lin Z, Makielski KR, Lee DL, Lambert PF, Johannsen EC, Kenney SC, Mertz JE. PLoS Pathog. 2017 Jun 15;13(6):e1006404. doi: 10.1371/journal.ppat.1006404. eCollection 2017 Jun. PubMed |
Hypoxia induces cancer cell-specific chromatin interactions and increases MALAT1 expression in breast cancer cells. Stone JK, Kim JH, Vukadin L, Richard A, Giannini HK, Lim SS, Tan M, Ahn EE. J Biol Chem. 2019 Jul 19;294(29):11213-11224. doi: 10.1074/jbc.RA118.006889. Epub 2019 Jun 5. PubMed |
MYC Regulates the HIF2alpha Stemness Pathway via Nanog and Sox2 to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells. Das B, Pal B, Bhuyan R, Li H, Sarma A, Gayan S, Talukdar J, Sandhya S, Bhuyan S, Gogoi G, Gouw AM, Baishya D, Gotlib JR, Kataki AC, Felsher DW. Cancer Res. 2019 Jul 2. pii: 0008-5472.CAN-18-2847. doi: 10.1158/0008-5472.CAN-18-2847. PubMed |
A hierarchical network of hypoxia-inducible factor and SMAD proteins governs procollagen lysyl hydroxylase 2 induction by hypoxia and transforming growth factor beta1. Rosell-Garcia T, Palomo-Alvarez O, Rodriguez-Pascual F. J Biol Chem. 2019 Sep 27;294(39):14308-14318. doi: 10.1074/jbc.RA119.007674. Epub 2019 Aug 7. PubMed |
DEAD Box Protein Family Member DDX28 Is a Negative Regulator of Hypoxia-Inducible Factor 2alpha- and Eukaryotic Initiation Factor 4E2-Directed Hypoxic Translation. Evagelou SL, Bebenek O, Specker EJ, Uniacke J. Mol Cell Biol. 2020 Feb 27;40(6). pii: MCB.00610-19. doi: 10.1128/MCB.00610-19. Print 2020 Feb 27. PubMed |
Hypoxia-Induced MALAT1 Promotes the Proliferation and Migration of Breast Cancer Cells by Sponging MiR-3064-5p. Shih CH, Chuang LL, Tsai MH, Chen LH, Chuang EY, Lu TP, Lai LC. Front Oncol. 2021 May 3;11:658151. doi: 10.3389/fonc.2021.658151. eCollection 2021. PubMed |
HIF2 Regulates Intestinal Wnt5a Expression. Garcia Garcia CJ, Acevedo Diaz AC, Kumari N, Govindaraju S, de la Cruz Bonilla M, San Lucas FA, Nguyen ND, Jimenez Sacarello I, Piwnica-Worms H, Maitra A, Taniguchi CM. Front Oncol. 2021 Nov 25;11:769385. doi: 10.3389/fonc.2021.769385. eCollection 2021. PubMed |
Hypoxia-induced HIF1alpha activation regulates small extracellular vesicle release in human embryonic kidney cells. Muniz-Garcia A, Romero M, Falcomicronn-Perez JM, Murray P, Zorzano A, Mora S. Sci Rep. 2022 Jan 27;12(1):1443. doi: 10.1038/s41598-022-05161-7. PubMed |
Hypoxia-Reoxygenation Couples 3betaHSD1 Enzyme and Cofactor Upregulation to Facilitate Androgen Biosynthesis and Hormone Therapy Resistance in Prostate Cancer. Qin L, Chung YM, Berk M, Naelitz B, Zhu Z, Klein E, Chakraborty AA, Sharifi N. Cancer Res. 2022 Jul 5;82(13):2417-2430. doi: 10.1158/0008-5472.CAN-21-4256. PubMed |
Regulatory mechanisms and function of hypoxia-induced long noncoding RNA NDRG1-OT1 in breast cancer cells. Chao HH, Luo JL, Hsu MH, Chen LH, Lu TP, Tsai MH, Chuang EY, Chuang LL, Lai LC. Cell Death Dis. 2022 Sep 20;13(9):807. doi: 10.1038/s41419-022-05253-2. PubMed |
Deficiency in PHD2-mediated hydroxylation of HIF2alpha underlies Pacak-Zhuang syndrome. Ferens FG, Taber CC, Stuart S, Hubert M, Tarade D, Lee JE, Ohh M. Commun Biol. 2024 Feb 28;7(1):240. doi: 10.1038/s42003-024-05904-4. PubMed |
The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury. Ruan W, Li T, Lee J, Bang IH, Deng W, Ma X, Yoo SH, Kim B, Li J, Yuan X, An YA, Wang YY, Liang Y, Deberge M, Zhang D, Zhou Z, Wang Y, Gorham J, Seidman JG, Seidman CE, Aranki SF, Nair R, Li L, Narula J, Zhao Z, Abebe AG, Muehlschlegel JD, Tsai KL, Eltzschig HK. Res Sq [Preprint]. 2024 Feb 28:rs.3.rs-3938716. doi: 10.21203/rs.3.rs-3938716/v1. PubMed |
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