Cdc2-HA Citations (8)
Originally described in: Distinct roles for cyclin-dependent kinases in cell cycle control.van den Heuvel S, Harlow E Science 1993 Dec 24;262(5142):2050-4. PubMed Journal
Articles Citing Cdc2-HA
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CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells.
Wei Y, Chen YH, Li LY, Lang J, Yeh SP, Shi B, Yang CC, Yang JY, Lin CY, Lai CC, Hung MC.
Nat Cell Biol. 2011 Jan . 13(1):87-94.
PubMed
Associated Plasmids |
Checkpoint kinase 1 prevents cell cycle exit linked to terminal cell differentiation. Ullah Z, de Renty C, DePamphilis ML. Mol Cell Biol. 2011 Oct;31(19):4129-43. doi: 10.1128/MCB.05723-11. Epub 2011 Jul 26. PubMed |
Inhibition of E2F1/CDK1 pathway attenuates neuronal apoptosis in vitro and confers neuroprotection after spinal cord injury in vivo. Wu J, Kharebava G, Piao C, Stoica BA, Dinizo M, Sabirzhanov B, Hanscom M, Guanciale K, Faden AI. PLoS One. 2012;7(7):e42129. doi: 10.1371/journal.pone.0042129. Epub 2012 Jul 25. PubMed |
Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking. Du Y, Shen J, Hsu JL, Han Z, Hsu MC, Yang CC, Kuo HP, Wang YN, Yamaguchi H, Miller SA, Hung MC. Oncogene. 2014 Feb 6;33(6):756-70. doi: 10.1038/onc.2013.1. Epub 2013 Feb 4. PubMed |
CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. Ortmann B, Bensaddek D, Carvalhal S, Moser SC, Mudie S, Griffis ER, Swedlow JR, Lamond AI, Rocha S. J Cell Sci. 2016 Jan 1;129(1):191-205. doi: 10.1242/jcs.179911. Epub 2015 Dec 7. PubMed |
Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry. Mazzolini L, Broban A, Froment C, Burlet-Schiltz O, Besson A, Manenti S, Dozier C. Cell Cycle. 2016 Oct 17;15(20):2742-52. doi: 10.1080/15384101.2016.1220455. Epub 2016 Aug 11. PubMed |
The tyrosine kinase v-Src causes mitotic slippage by phosphorylating an inhibitory tyrosine residue of Cdk1. Horiuchi M, Kuga T, Saito Y, Nagano M, Adachi J, Tomonaga T, Yamaguchi N, Nakayama Y. J Biol Chem. 2018 Oct 5;293(40):15524-15537. doi: 10.1074/jbc.RA118.002784. Epub 2018 Aug 22. PubMed |
ATR Inhibition Induces CDK1-SPOP Signaling and Enhances Anti-PD-L1 Cytotoxicity in Prostate Cancer. Tang Z, Pilie PG, Geng C, Manyam GC, Yang G, Park S, Wang D, Peng S, Wu C, Peng G, Yap TA, Corn PG, Broom BM, Thompson TC. Clin Cancer Res. 2021 Sep 1;27(17):4898-4909. doi: 10.1158/1078-0432.CCR-21-1010. Epub 2021 Jun 24. PubMed |
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