Cdk2-HA Citations (15)
Originally described in: Distinct roles for cyclin-dependent kinases in cell cycle control.van den Heuvel S, Harlow E Science 1993 Dec 24;262(5142):2050-4. PubMed Journal
Articles Citing Cdk2-HA
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cAMP-mediated induction of cyclin E sensitizes growth-arrested adipose stem cells to DNA damage-induced apoptosis. Ugland H, Boquest AC, Naderi S, Collas P, Blomhoff HK. Mol Biol Cell. 2008 Dec;19(12):5082-92. doi: 10.1091/mbc.E08-01-0094. Epub 2008 Sep 17. PubMed |
Serine phosphorylation regulates disabled-1 early isoform turnover independently of Reelin. Gao Z, Godbout R. Cell Signal. 2011 Mar;23(3):555-65. doi: 10.1016/j.cellsig.2010.11.007. Epub 2010 Nov 25. PubMed |
Cdk-mediated phosphorylation of the Kvbeta2 auxiliary subunit regulates Kv1 channel axonal targeting. Vacher H, Yang JW, Cerda O, Autillo-Touati A, Dargent B, Trimmer JS. J Cell Biol. 2011 Mar 7;192(5):813-24. doi: 10.1083/jcb.201007113. Epub 2011 Feb 28. PubMed |
CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells. Wright RH, Castellano G, Bonet J, Le Dily F, Font-Mateu J, Ballare C, Nacht AS, Soronellas D, Oliva B, Beato M. Genes Dev. 2012 Sep 1;26(17):1972-83. doi: 10.1101/gad.193193.112. PubMed |
A chrysin derivative suppresses skin cancer growth by inhibiting cyclin-dependent kinases. Liu H, Liu K, Huang Z, Park CM, Thimmegowda NR, Jang JH, Ryoo IJ, He L, Kim SO, Oi N, Lee KW, Soung NK, Bode AM, Yang Y, Zhou X, Erikson RL, Ahn JS, Hwang J, Kim KE, Dong Z, Kim BY. J Biol Chem. 2013 Sep 6;288(36):25924-37. doi: 10.1074/jbc.M113.464669. Epub 2013 Jul 25. PubMed |
CDK2 transcriptional repression is an essential effector in p53-dependent cellular senescence-implications for therapeutic intervention. Zalzali H, Nasr B, Harajly M, Basma H, Ghamloush F, Ghayad S, Ghanem N, Evan GI, Saab R. Mol Cancer Res. 2015 Jan;13(1):29-40. doi: 10.1158/1541-7786.MCR-14-0163. Epub 2014 Aug 22. PubMed |
CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. Ortmann B, Bensaddek D, Carvalhal S, Moser SC, Mudie S, Griffis ER, Swedlow JR, Lamond AI, Rocha S. J Cell Sci. 2016 Jan 1;129(1):191-205. doi: 10.1242/jcs.179911. Epub 2015 Dec 7. PubMed |
Covalent Modification of CDK2 by 4-Hydroxynonenal as a Mechanism of Inhibition of Cell Cycle Progression. Camarillo JM, Rose KL, Galligan JJ, Xu S, Marnett LJ. Chem Res Toxicol. 2016 Mar 21;29(3):323-32. doi: 10.1021/acs.chemrestox.5b00485. Epub 2016 Mar 11. PubMed |
Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry. Mazzolini L, Broban A, Froment C, Burlet-Schiltz O, Besson A, Manenti S, Dozier C. Cell Cycle. 2016 Oct 17;15(20):2742-52. doi: 10.1080/15384101.2016.1220455. Epub 2016 Aug 11. PubMed |
NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres. Rai R, Hu C, Broton C, Chen Y, Lei M, Chang S. Mol Cell. 2017 Mar 2;65(5):801-817.e4. doi: 10.1016/j.molcel.2017.01.016. Epub 2017 Feb 16. PubMed |
Phosphorylation of transcriptional regulators in the retinoblastoma protein pathway by UL97, the viral cyclin-dependent kinase encoded by human cytomegalovirus. Iwahori S, Kalejta RF. Virology. 2017 Dec;512:95-103. doi: 10.1016/j.virol.2017.09.009. PubMed |
Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk). Umana AC, Iwahori S, Kalejta RF. ACS Chem Biol. 2018 Jan 19;13(1):189-199. doi: 10.1021/acschembio.7b00972. Epub 2017 Dec 19. PubMed |
Inhibition of cyclin-dependent kinase 2 protects against doxorubicin-induced cardiomyocyte apoptosis and cardiomyopathy. Xia P, Liu Y, Chen J, Coates S, Liu DX, Cheng Z. J Biol Chem. 2018 Dec 21;293(51):19672-19685. doi: 10.1074/jbc.RA118.004673. Epub 2018 Oct 25. PubMed |
Doxorubicin induces cardiomyocyte apoptosis and atrophy through cyclin-dependent kinase 2-mediated activation of forkhead box O1. Xia P, Chen J, Liu Y, Fletcher M, Jensen BC, Cheng Z. J Biol Chem. 2020 Mar 27;295(13):4265-4276. doi: 10.1074/jbc.RA119.011571. Epub 2020 Feb 19. PubMed |
Intra-S phase checkpoint kinase Chk1 dissociates replication proteins Treslin and TopBP1 through multiple mechanisms during replication stress. Kelly RL, Huehls AM, Venkatachalam A, Huntoon CJ, Machida YJ, Karnitz LM. J Biol Chem. 2022 Apr;298(4):101777. doi: 10.1016/j.jbc.2022.101777. Epub 2022 Feb 26. PubMed |
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